Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
Identifieur interne : 005329 ( Main/Exploration ); précédent : 005328; suivant : 005330Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
Auteurs : Andrew P. Morris [Royaume-Uni] ; Benjamin F. Voight [États-Unis] ; Tanya M. Teslovich [États-Unis] ; Teresa Ferreira [Royaume-Uni] ; Ayellet V. Segrè [États-Unis] ; Valgerdur Steinthorsdottir [Islande] ; Rona J. Strawbridge [Suède] ; Hassan Khan [Royaume-Uni] ; Harald Grallert [Allemagne] ; Anubha Mahajan [Royaume-Uni] ; Inga Prokopenko [Royaume-Uni] ; Hyun Min Kang [États-Unis] ; Christian Dina [France] ; Tonu Esko [Estonie] ; Ross M. Fraser [Royaume-Uni] ; Stavroula Kanoni [Royaume-Uni] ; Ashish Kumar [Royaume-Uni] ; Vasiliki Lagou [Royaume-Uni] ; Claudia Langenberg [Royaume-Uni] ; Jian'An Luan [Royaume-Uni] ; Cecilia M. Lindgren [Royaume-Uni] ; Martina Müller-Nurasyid [Allemagne] ; Sonali Pechlivanis [Allemagne] ; N William Rayner [Royaume-Uni] ; Laura J. Scott [États-Unis] ; Steven Wiltshire [Royaume-Uni] ; Loic Yengo [France] ; Leena Kinnunen [Finlande] ; Elizabeth J. Rossin [États-Unis] ; Soumya Raychaudhuri [États-Unis] ; Andrew D. Johnson [États-Unis] ; Antigone S. Dimas [Royaume-Uni, Suisse, Grèce] ; Ruth J F. Loos [Royaume-Uni, États-Unis] ; Sailaja Vedantam [États-Unis] ; Han Chen [États-Unis] ; Jose C. Florez [États-Unis] ; Caroline Fox [États-Unis] ; Ching-Ti Liu [États-Unis] ; Denis Rybin [États-Unis] ; David J. Couper [États-Unis] ; Wen Hong L. Kao [États-Unis] ; Man Li [États-Unis] ; Marilyn C. Cornelis [États-Unis] ; Peter Kraft [États-Unis] ; Qi Sun [États-Unis] ; Rob M. Van Dam [États-Unis, Singapour] ; Heather M. Stringham [États-Unis] ; Peter S. Chines [États-Unis] ; Krista Fischer [Estonie] ; Pierre Fontanillas [États-Unis] ; Oddgeir L. Holmen [Norvège] ; Sarah E. Hunt [Royaume-Uni] ; Anne U. Jackson [États-Unis] ; Augustine Kong [Islande] ; Robert Lawrence [Australie] ; Julia Meyer [Allemagne] ; John Rb Perry [Royaume-Uni] ; Carl Gp Platou [Norvège] ; Simon Potter [Royaume-Uni] ; Emil Rehnberg [Suède] ; Neil Robertson [Royaume-Uni] ; Suthesh Sivapalaratnam [Pays-Bas] ; Alena Stan Ková [Finlande] ; Kathleen Stirrups [Royaume-Uni] ; Gudmar Thorleifsson [Islande] ; Emmi Tikkanen [Finlande] ; Andrew R. Wood [Royaume-Uni] ; Peter Almgren [Suède] ; Mustafa Atalay [Finlande] ; Rafn Benediktsson [Islande] ; Lori L. Bonnycastle [États-Unis] ; Noël Burtt [États-Unis] ; Jason Carey [États-Unis] ; Guillaume Charpentier [France] ; Andrew T. Crenshaw [États-Unis] ; Alex S F. Doney [Royaume-Uni] ; Mozhgan Dorkhan [Suède] ; Sarah Edkins [Royaume-Uni] ; Valur Emilsson [Islande] ; Elodie Eury [France] ; Tom Forsen [Finlande] ; Karl Gertow [Suède] ; Bruna Gigante [Suède] ; George B. Grant [États-Unis] ; Christopher J. Groves [Royaume-Uni] ; Candace Guiducci [États-Unis] ; Christian Herder [Allemagne] ; Astradur B. Hreidarsson [Islande] ; Jennie Hui [Australie] ; Alan James [Australie] ; Anna Jonsson [Suède] ; Wolfgang Rathmann [Allemagne] ; Norman Klopp [Allemagne] ; Jasmina Kravic [Suède] ; Kaarel Krjutškov [Estonie] ; Cordelia Langford [Royaume-Uni] ; Karin Leander [Suède] ; Eero Lindholm [Suède] ; Stéphane Lobbens [France] ; Satu M Nnistö [Finlande] ; Ghazala Mirza [Royaume-Uni] ; Thomas W. Mühleisen [Allemagne] ; Bill Musk [Australie] ; Melissa Parkin [États-Unis] ; Loukianos Rallidis [Grèce] ; Jouko Saramies [Finlande] ; Bengt Sennblad [Suède] ; Sonia Shah [Royaume-Uni] ; Gunnar Sigur Sson [Islande] ; Angela Silveira [Suède] ; Gerald Steinbach [Allemagne] ; Barbara Thorand [Allemagne] ; Joseph Trakalo [Royaume-Uni] ; Fabrizio Veglia [Italie] ; Roman Wennauer [Allemagne] ; Wendy Winckler [États-Unis] ; Delilah Zabaneh [Royaume-Uni] ; Harry Campbell [Royaume-Uni] ; Cornelia Van Duijn [Pays-Bas] ; Andre G. Uitterlinden89- [Pays-Bas] ; Albert Hofman [Pays-Bas] ; Eric Sijbrands [Pays-Bas] ; Goncalo R. Abecasis [États-Unis] ; Katharine R. Owen [Royaume-Uni] ; Eleftheria Zeggini [Royaume-Uni] ; Mieke D. Trip [Pays-Bas] ; Nita G. Forouhi [Royaume-Uni] ; Ann-Christine Syv Nen [Suède] ; Johan G. Eriksson [Finlande] ; Leena Peltonen [États-Unis, Royaume-Uni, Finlande] ; Markus M. Nöthen [Allemagne] ; Beverley Balkau [France] ; Colin N A. Palmer [Royaume-Uni] ; Valeriya Lyssenko [Suède] ; Tiinamaija Tuomi [Finlande] ; Bo Isomaa [Finlande] ; David J. Hunter [États-Unis] ; Lu Qi [États-Unis] ; Alan R. Shuldiner [États-Unis] ; Michael Roden [Allemagne] ; Ines Barroso [Royaume-Uni] ; Tom Wilsgaard [Norvège] ; John Beilby [Australie] ; Kees Hovingh [Pays-Bas] ; Jackie F. Price [Royaume-Uni] ; James F. Wilson [Royaume-Uni] ; Rainer Rauramaa [Finlande] ; Timo A. Lakka [Finlande] ; Lars Lind [Suède] ; George Dedoussis [Grèce] ; Inger Nj Lstad [Norvège] ; Nancy L. Pedersen [Suède] ; Kay-Tee Khaw [Royaume-Uni] ; Nicholas J. Wareham [Royaume-Uni] ; Sirkka M. Keinanen-Kiukaanniemi [Finlande] ; Timo E. Saaristo [Finlande] ; Eeva Korpi-Hyöv Lti [Finlande] ; Juha Saltevo [Finlande] ; Markku Laakso [Finlande] ; Johanna Kuusisto [Finlande] ; Andres Metspalu [Estonie] ; Francis S. Collins [États-Unis] ; Karen L. Mohlke [États-Unis] ; Richard N. Bergman [États-Unis] ; Jaakko Tuomilehto [Finlande, Espagne, Autriche] ; Bernhard O. Boehm [Allemagne] ; Christian Gieger [Allemagne] ; Kristian Hveem [Norvège] ; Stephane Cauchi [France] ; Philippe Froguel [France, Royaume-Uni] ; Damiano Baldassarre [Italie] ; Elena Tremoli [Italie] ; Steve E. Humphries [Royaume-Uni] ; Danish Saleheen [Royaume-Uni, Pakistan] ; John Danesh [Royaume-Uni] ; Erik Ingelsson [Suède] ; Samuli Ripatti [Royaume-Uni, Finlande] ; Veikko Salomaa [Finlande] ; Raimund Erbel [Allemagne] ; Karl-Heinz Jöckel [Allemagne] ; Susanne Moebus [Allemagne] ; Annette Peters [Allemagne] ; Thomas Illig [Allemagne] ; Ulf De Faire [Suède] ; Anders Hamsten [Suède] ; Andrew D. Morris [Royaume-Uni] ; Peter J. Donnelly [Royaume-Uni] ; Timothy M. Frayling [Royaume-Uni] ; Andrew T. Hattersley [Royaume-Uni] ; Eric Boerwinkle [États-Unis] ; Olle Melander [Suède] ; Sekar Kathiresan [États-Unis] ; Peter M. Nilsson [Suède] ; Panos Deloukas [Royaume-Uni] ; Unnur Thorsteinsdottir [Islande] ; Leif C. Groop [Suède] ; Kari Stefansson [Islande] ; Frank Hu [États-Unis] ; James S. Pankow [États-Unis] ; Josée Dupuis [États-Unis] ; James B. Meigs [États-Unis] ; David Altshuler [États-Unis] ; Michael Boehnke [États-Unis] ; Mark I. Mccarthy [Royaume-Uni]Source :
- Nature genetics [ 1061-4036 ] ; 2012.
Abstract
To extend understanding of the genetic architecture and molecular basis of type 2 diabetes (T2D), we conducted a meta-analysis of genetic variants on the Metabochip involving 34,840 cases and 114,981 controls, overwhelmingly of European descent. We identified ten previously unreported T2D susceptibility loci, including two demonstrating sex-differentiated association. Genome-wide analyses of these data are consistent with a long tail of further common variant loci explaining much of the variation in susceptibility to T2D. Exploration of the enlarged set of susceptibility loci implicates several processes, including CREBBP-related transcription, adipocytokine signalling and cell cycle regulation, in diabetes pathogenesis.
Url:
DOI: 10.1038/ng.2383
PubMed: 22885922
PubMed Central: 3442244
Affiliations:
- Allemagne, Australie, Autriche, Espagne, Estonie, Finlande, France, Grèce, Islande, Italie, Norvège, Pakistan, Pays-Bas, Royaume-Uni, Singapour, Suisse, Suède, États-Unis
- Angleterre, Angleterre de l'Est, Attique (région), Bade-Wurtemberg, Basse-Saxe, Bavière, Californie, Caroline du Nord, Communauté de Madrid, District de Cologne, District de Düsseldorf, District de Haute-Bavière, District de Tübingen, East Middle Sweden, Grand Londres, Hauts-de-France, Hollande-Méridionale, Hollande-Septentrionale, Lombardie, Maryland, Massachusetts, Michigan, Minnesota, Nord-Pas-de-Calais, Oxfordshire, Pays de la Loire, Pennsylvanie, Rhénanie-du-Nord-Westphalie, Svealand, Texas, Uusimaa, Écosse, État de New York
- Amsterdam, Athènes, Bonn, Cambridge, Cambridge (Massachusetts), Chapel Hill (Caroline du Nord), Düsseldorf, Hanovre, Helsinki, Lille, Londres, Madrid, Milan, Munich, Nantes, Oxford, Rotterdam, Stockholm, Ulm, Uppsala, Édimbourg
- University College de Londres, Université Harokopio, Université Harvard, Université d'Amsterdam, Université d'Helsinki, Université d'Oxford, Université d'Ulm, Université d'Uppsala, Université d'Édimbourg, Université de Cambridge, Université de Caroline du Nord à Chapel Hill, Université nationale de Singapour
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Le document en format XML
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id="A13">Inserm UMR 1087, Nantes, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Inserm UMR 1087, Nantes</wicri:regionArea><placeName><region type="region">Pays de la Loire</region><region type="old region">Pays de la Loire</region><settlement type="city">Nantes</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A14">CNRS UMR 6291, Nantes, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>CNRS UMR 6291, Nantes</wicri:regionArea><placeName><region type="region">Pays de la Loire</region><region type="old region">Pays de la Loire</region><settlement type="city">Nantes</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A15">Nantes University, Nantes, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Nantes University, Nantes</wicri:regionArea><placeName><region type="region">Pays de la Loire</region><region type="old region">Pays de la Loire</region><settlement type="city">Nantes</settlement></placeName></affiliation></author><author><name sortKey="Esko, Tonu" sort="Esko, Tonu" uniqKey="Esko T" first="Tonu" last="Esko">Tonu Esko</name><affiliation wicri:level="1"><nlm:aff id="A16">Estonian Genome Center, University of Tartu, Tartu, Estonia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Estonie</country><wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A17">Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Estonie</country><wicri:regionArea>Institute of Molecular and Cell Biology, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation></author><author><name sortKey="Fraser, Ross M" sort="Fraser, Ross M" uniqKey="Fraser R" first="Ross M" last="Fraser">Ross M. Fraser</name><affiliation wicri:level="4"><nlm:aff id="A18">Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Kanoni, Stavroula" sort="Kanoni, Stavroula" uniqKey="Kanoni S" first="Stavroula" last="Kanoni">Stavroula Kanoni</name><affiliation wicri:level="1"><nlm:aff id="A19">Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Kumar, Ashish" sort="Kumar, Ashish" uniqKey="Kumar A" first="Ashish" last="Kumar">Ashish Kumar</name><affiliation wicri:level="4"><nlm:aff id="A1">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Lagou, Vasiliki" sort="Lagou, Vasiliki" uniqKey="Lagou V" first="Vasiliki" last="Lagou">Vasiliki Lagou</name><affiliation wicri:level="4"><nlm:aff id="A1">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Langenberg, Claudia" sort="Langenberg, Claudia" uniqKey="Langenberg C" first="Claudia" last="Langenberg">Claudia Langenberg</name><affiliation wicri:level="1"><nlm:aff id="A20">MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Luan, Jian An" sort="Luan, Jian An" uniqKey="Luan J" first="Jian'An" last="Luan">Jian'An Luan</name><affiliation wicri:level="1"><nlm:aff id="A20">MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Lindgren, Cecilia M" sort="Lindgren, Cecilia M" uniqKey="Lindgren C" first="Cecilia M" last="Lindgren">Cecilia M. Lindgren</name><affiliation wicri:level="4"><nlm:aff id="A1">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Muller Nurasyid, Martina" sort="Muller Nurasyid, Martina" uniqKey="Muller Nurasyid M" first="Martina" last="Müller-Nurasyid">Martina Müller-Nurasyid</name><affiliation wicri:level="3"><nlm:aff id="A21">Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A22">Institute of Genetic Epidemiology, Helmholtz Zentrum Muenchen, Neuherberg, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum Muenchen, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A23">Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-University, Munich, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-University, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName></affiliation></author><author><name sortKey="Pechlivanis, Sonali" sort="Pechlivanis, Sonali" uniqKey="Pechlivanis S" first="Sonali" last="Pechlivanis">Sonali Pechlivanis</name><affiliation wicri:level="1"><nlm:aff id="A24">Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, University Duisburg-Essen, Essen, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, University Duisburg-Essen, Essen</wicri:regionArea><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author><author><name sortKey="Rayner, N William" sort="Rayner, N William" uniqKey="Rayner N" first="N William" last="Rayner">N William Rayner</name><affiliation wicri:level="4"><nlm:aff id="A1">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A12">Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Scott, Laura J" sort="Scott, Laura J" uniqKey="Scott L" first="Laura J" last="Scott">Laura J. Scott</name><affiliation wicri:level="2"><nlm:aff id="A4">Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Biostatistics, University of Michigan, Ann Arbor, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Wiltshire, Steven" sort="Wiltshire, Steven" uniqKey="Wiltshire S" first="Steven" last="Wiltshire">Steven Wiltshire</name><affiliation wicri:level="4"><nlm:aff id="A1">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Yengo, Loic" sort="Yengo, Loic" uniqKey="Yengo L" first="Loic" last="Yengo">Loic Yengo</name><affiliation wicri:level="3"><nlm:aff id="A25">CNRS-UMR-8199, Institute of Biology and Lille 2 University, Pasteur Institute, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>CNRS-UMR-8199, Institute of Biology and Lille 2 University, Pasteur Institute, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A26">University Lille 1, Laboratory of Mathematics, CNRS-UMR 8524, MODAL team, INRIA Lille Nord-Europe, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>University Lille 1, Laboratory of Mathematics, CNRS-UMR 8524, MODAL team, INRIA Lille Nord-Europe, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation></author><author><name sortKey="Kinnunen, Leena" sort="Kinnunen, Leena" uniqKey="Kinnunen L" first="Leena" last="Kinnunen">Leena Kinnunen</name><affiliation wicri:level="1"><nlm:aff id="A27">Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Rossin, Elizabeth J" sort="Rossin, Elizabeth J" uniqKey="Rossin E" first="Elizabeth J" last="Rossin">Elizabeth J. Rossin</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A5">Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A28">Health Science and Technology MD Program, Harvard University and Massachusetts Institute of Technology, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Health Science and Technology MD Program, Harvard University and Massachusetts Institute of Technology, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A29">Harvard Biological and Biomedical Sciences Program, Harvard University, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Harvard Biological and Biomedical Sciences Program, Harvard University, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region><settlement type="city">Cambridge (Massachusetts)</settlement></placeName><orgName type="university">Université Harvard</orgName></affiliation></author><author><name sortKey="Raychaudhuri, Soumya" sort="Raychaudhuri, Soumya" uniqKey="Raychaudhuri S" first="Soumya" last="Raychaudhuri">Soumya Raychaudhuri</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A30">Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A31">Partners Center for Personalized Genomic Medicine, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Partners Center for Personalized Genomic Medicine, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Johnson, Andrew D" sort="Johnson, Andrew D" uniqKey="Johnson A" first="Andrew D" last="Johnson">Andrew D. Johnson</name><affiliation wicri:level="2"><nlm:aff id="A32">National Heart, Lung, and Blood Institute’s Framingham Heart Study, Framingham, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>National Heart, Lung, and Blood Institute’s Framingham Heart Study, Framingham, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Dimas, Antigone S" sort="Dimas, Antigone S" uniqKey="Dimas A" first="Antigone S" last="Dimas">Antigone S. Dimas</name><affiliation wicri:level="4"><nlm:aff id="A1">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation><affiliation wicri:level="1"><nlm:aff id="A33">Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suisse</country><wicri:regionArea>Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva</wicri:regionArea><wicri:noRegion>Geneva</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A34">Biomedical Sciences Research Center Al. Fleming, Vari, Greece.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Grèce</country><wicri:regionArea>Biomedical Sciences Research Center Al. Fleming, Vari</wicri:regionArea><wicri:noRegion>Vari</wicri:noRegion></affiliation></author><author><name sortKey="Loos, Ruth J F" sort="Loos, Ruth J F" uniqKey="Loos R" first="Ruth J F" last="Loos">Ruth J F. Loos</name><affiliation wicri:level="1"><nlm:aff id="A20">MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation><affiliation wicri:level="2"><nlm:aff id="A35">Charles R. Bronfman Institute for Personalized Medicine, Mount Sinai School of Medicine, New York, New York, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Charles R. Bronfman Institute for Personalized Medicine, Mount Sinai School of Medicine, New York, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A36">Child Health and Development Institute, Mount Sinai School of Medicine, New York, New York, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Child Health and Development Institute, Mount Sinai School of Medicine, New York, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A37">Department of Preventive Medicine, Mount Sinai School of Medicine, New York, New York, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Preventive Medicine, Mount Sinai School of Medicine, New York, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Vedantam, Sailaja" sort="Vedantam, Sailaja" uniqKey="Vedantam S" first="Sailaja" last="Vedantam">Sailaja Vedantam</name><affiliation wicri:level="2"><nlm:aff id="A38">Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A39">Division of Genetics and Endocrinology, Children's Hospital, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Division of Genetics and Endocrinology, Children's Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Chen, Han" sort="Chen, Han" uniqKey="Chen H" first="Han" last="Chen">Han Chen</name><affiliation wicri:level="2"><nlm:aff id="A40">Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Florez, Jose C" sort="Florez, Jose C" uniqKey="Florez J" first="Jose C" last="Florez">Jose C. Florez</name><affiliation wicri:level="2"><nlm:aff id="A5">Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A6">Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Medicine, Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A38">Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A41">Diabetes Research Center, Diabetes Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Diabetes Research Center, Diabetes Unit, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Fox, Caroline" sort="Fox, Caroline" uniqKey="Fox C" first="Caroline" last="Fox">Caroline Fox</name><affiliation wicri:level="2"><nlm:aff id="A32">National Heart, Lung, and Blood Institute’s Framingham Heart Study, Framingham, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>National Heart, Lung, and Blood Institute’s Framingham Heart Study, Framingham, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A42">Division of Endocrinology and Metabolism, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Division of Endocrinology and Metabolism, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Liu, Ching Ti" sort="Liu, Ching Ti" uniqKey="Liu C" first="Ching-Ti" last="Liu">Ching-Ti Liu</name><affiliation wicri:level="2"><nlm:aff id="A40">Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Rybin, Denis" sort="Rybin, Denis" uniqKey="Rybin D" first="Denis" last="Rybin">Denis Rybin</name><affiliation wicri:level="2"><nlm:aff id="A43">Boston University Data Coordinating Center, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Boston University Data Coordinating Center, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Couper, David J" sort="Couper, David J" uniqKey="Couper D" first="David J" last="Couper">David J. Couper</name><affiliation wicri:level="4"><nlm:aff id="A44">Collaborative Studies Coordinating Center, Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Collaborative Studies Coordinating Center, Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina</wicri:regionArea><placeName><region type="state">Caroline du Nord</region><settlement type="city">Chapel Hill (Caroline du Nord)</settlement></placeName><orgName type="university">Université de Caroline du Nord à Chapel Hill</orgName></affiliation></author><author><name sortKey="Kao, Wen Hong L" sort="Kao, Wen Hong L" uniqKey="Kao W" first="Wen Hong L" last="Kao">Wen Hong L. Kao</name><affiliation wicri:level="2"><nlm:aff id="A45">Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Li, Man" sort="Li, Man" uniqKey="Li M" first="Man" last="Li">Man Li</name><affiliation wicri:level="2"><nlm:aff id="A45">Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Cornelis, Marilyn C" sort="Cornelis, Marilyn C" uniqKey="Cornelis M" first="Marilyn C" last="Cornelis">Marilyn C. Cornelis</name><affiliation wicri:level="2"><nlm:aff id="A46">Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Kraft, Peter" sort="Kraft, Peter" uniqKey="Kraft P" first="Peter" last="Kraft">Peter Kraft</name><affiliation wicri:level="2"><nlm:aff id="A46">Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A47">Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Sun, Qi" sort="Sun, Qi" uniqKey="Sun Q" first="Qi" last="Sun">Qi Sun</name><affiliation wicri:level="2"><nlm:aff id="A46">Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A48">Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Van Dam, Rob M" sort="Van Dam, Rob M" uniqKey="Van Dam R" first="Rob M" last="Van Dam">Rob M. Van Dam</name><affiliation wicri:level="2"><nlm:aff id="A46">Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A49">Saw Swee Hock School of Public Health, National University of Singapore, Singapore.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Singapour</country><wicri:regionArea>Saw Swee Hock School of Public Health, National University of Singapore</wicri:regionArea><orgName type="university">Université nationale de Singapour</orgName></affiliation></author><author><name sortKey="Stringham, Heather M" sort="Stringham, Heather M" uniqKey="Stringham H" first="Heather M" last="Stringham">Heather M. Stringham</name><affiliation wicri:level="2"><nlm:aff id="A4">Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Biostatistics, University of Michigan, Ann Arbor, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Chines, Peter S" sort="Chines, Peter S" uniqKey="Chines P" first="Peter S" last="Chines">Peter S. Chines</name><affiliation wicri:level="2"><nlm:aff id="A50">National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Fischer, Krista" sort="Fischer, Krista" uniqKey="Fischer K" first="Krista" last="Fischer">Krista Fischer</name><affiliation wicri:level="1"><nlm:aff id="A16">Estonian Genome Center, University of Tartu, Tartu, Estonia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Estonie</country><wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation></author><author><name sortKey="Fontanillas, Pierre" sort="Fontanillas, Pierre" uniqKey="Fontanillas P" first="Pierre" last="Fontanillas">Pierre Fontanillas</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Holmen, Oddgeir L" sort="Holmen, Oddgeir L" uniqKey="Holmen O" first="Oddgeir L" last="Holmen">Oddgeir L. Holmen</name><affiliation wicri:level="1"><nlm:aff id="A51">HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Norvège</country><wicri:regionArea>HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger</wicri:regionArea><wicri:noRegion>Levanger</wicri:noRegion></affiliation></author><author><name sortKey="Hunt, Sarah E" sort="Hunt, Sarah E" uniqKey="Hunt S" first="Sarah E" last="Hunt">Sarah E. Hunt</name><affiliation wicri:level="1"><nlm:aff id="A19">Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Jackson, Anne U" sort="Jackson, Anne U" uniqKey="Jackson A" first="Anne U" last="Jackson">Anne U. Jackson</name><affiliation wicri:level="2"><nlm:aff id="A4">Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Biostatistics, University of Michigan, Ann Arbor, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Kong, Augustine" sort="Kong, Augustine" uniqKey="Kong A" first="Augustine" last="Kong">Augustine Kong</name><affiliation wicri:level="1"><nlm:aff id="A7">deCODE Genetics, Reykjavik, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>deCODE Genetics, Reykjavik</wicri:regionArea><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation></author><author><name sortKey="Lawrence, Robert" sort="Lawrence, Robert" uniqKey="Lawrence R" first="Robert" last="Lawrence">Robert Lawrence</name><affiliation wicri:level="1"><nlm:aff id="A52">Centre for Genetic Epidemiology and Biostatistics, The University of Western Australia, Nedlands, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>Centre for Genetic Epidemiology and Biostatistics, The University of Western Australia, Nedlands</wicri:regionArea><wicri:noRegion>Nedlands</wicri:noRegion></affiliation></author><author><name sortKey="Meyer, Julia" sort="Meyer, Julia" uniqKey="Meyer J" first="Julia" last="Meyer">Julia Meyer</name><affiliation wicri:level="1"><nlm:aff id="A22">Institute of Genetic Epidemiology, Helmholtz Zentrum Muenchen, Neuherberg, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum Muenchen, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Perry, John Rb" sort="Perry, John Rb" uniqKey="Perry J" first="John Rb" last="Perry">John Rb Perry</name><affiliation wicri:level="4"><nlm:aff id="A1">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation><affiliation wicri:level="1"><nlm:aff id="A53">Genetics of Complex Traits, Institute of Biomedical and Clinical Science, Peninsula Medical School, University of Exeter, Magdalen Road, Exeter, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Genetics of Complex Traits, Institute of Biomedical and Clinical Science, Peninsula Medical School, University of Exeter, Magdalen Road, Exeter</wicri:regionArea><wicri:noRegion>Exeter</wicri:noRegion></affiliation></author><author><name sortKey="Platou, Carl Gp" sort="Platou, Carl Gp" uniqKey="Platou C" first="Carl Gp" last="Platou">Carl Gp Platou</name><affiliation wicri:level="1"><nlm:aff id="A51">HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Norvège</country><wicri:regionArea>HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger</wicri:regionArea><wicri:noRegion>Levanger</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A54">Department of Internal Medicine, Levanger Hospital, Nord-Trøndelag Health Trust, Levanger, Norway.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Norvège</country><wicri:regionArea>Department of Internal Medicine, Levanger Hospital, Nord-Trøndelag Health Trust, Levanger</wicri:regionArea><wicri:noRegion>Levanger</wicri:noRegion></affiliation></author><author><name sortKey="Potter, Simon" sort="Potter, Simon" uniqKey="Potter S" first="Simon" last="Potter">Simon Potter</name><affiliation wicri:level="1"><nlm:aff id="A19">Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Rehnberg, Emil" sort="Rehnberg, Emil" uniqKey="Rehnberg E" first="Emil" last="Rehnberg">Emil Rehnberg</name><affiliation wicri:level="3"><nlm:aff id="A55">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Robertson, Neil" sort="Robertson, Neil" uniqKey="Robertson N" first="Neil" last="Robertson">Neil Robertson</name><affiliation wicri:level="4"><nlm:aff id="A1">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A12">Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Sivapalaratnam, Suthesh" sort="Sivapalaratnam, Suthesh" uniqKey="Sivapalaratnam S" first="Suthesh" last="Sivapalaratnam">Suthesh Sivapalaratnam</name><affiliation wicri:level="4"><nlm:aff id="A56">Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region><settlement type="city">Amsterdam</settlement></placeName><orgName type="university">Université d'Amsterdam</orgName></affiliation></author><author><name sortKey="Stan Kova, Alena" sort="Stan Kova, Alena" uniqKey="Stan Kova A" first="Alena" last="Stan Ková">Alena Stan Ková</name><affiliation wicri:level="1"><nlm:aff id="A57">Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation></author><author><name sortKey="Stirrups, Kathleen" sort="Stirrups, Kathleen" uniqKey="Stirrups K" first="Kathleen" last="Stirrups">Kathleen Stirrups</name><affiliation wicri:level="1"><nlm:aff id="A19">Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Thorleifsson, Gudmar" sort="Thorleifsson, Gudmar" uniqKey="Thorleifsson G" first="Gudmar" last="Thorleifsson">Gudmar Thorleifsson</name><affiliation wicri:level="1"><nlm:aff id="A7">deCODE Genetics, Reykjavik, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>deCODE Genetics, Reykjavik</wicri:regionArea><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation></author><author><name sortKey="Tikkanen, Emmi" sort="Tikkanen, Emmi" uniqKey="Tikkanen E" first="Emmi" last="Tikkanen">Emmi Tikkanen</name><affiliation wicri:level="1"><nlm:aff id="A58">Institute for Molecular Medicine Finland (FIMM), Helsinki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Institute for Molecular Medicine Finland (FIMM), Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A59">Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Wood, Andrew R" sort="Wood, Andrew R" uniqKey="Wood A" first="Andrew R" last="Wood">Andrew R. Wood</name><affiliation wicri:level="1"><nlm:aff id="A53">Genetics of Complex Traits, Institute of Biomedical and Clinical Science, Peninsula Medical School, University of Exeter, Magdalen Road, Exeter, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Genetics of Complex Traits, Institute of Biomedical and Clinical Science, Peninsula Medical School, University of Exeter, Magdalen Road, Exeter</wicri:regionArea><wicri:noRegion>Exeter</wicri:noRegion></affiliation></author><author><name sortKey="Almgren, Peter" sort="Almgren, Peter" uniqKey="Almgren P" first="Peter" last="Almgren">Peter Almgren</name><affiliation wicri:level="1"><nlm:aff id="A60">Lund University Diabetes Centre, Department of Clinical Science Malmö, Scania University Hospital, Lund University, Malmö, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Lund University Diabetes Centre, Department of Clinical Science Malmö, Scania University Hospital, Lund University, Malmö</wicri:regionArea><wicri:noRegion>Malmö</wicri:noRegion></affiliation></author><author><name sortKey="Atalay, Mustafa" sort="Atalay, Mustafa" uniqKey="Atalay M" first="Mustafa" last="Atalay">Mustafa Atalay</name><affiliation wicri:level="1"><nlm:aff id="A61">Institute of Biomedicine, Physiology, University of Eastern Finland, Kuopio Campus, Kuopio, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Institute of Biomedicine, Physiology, University of Eastern Finland, Kuopio Campus, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation></author><author><name sortKey="Benediktsson, Rafn" sort="Benediktsson, Rafn" uniqKey="Benediktsson R" first="Rafn" last="Benediktsson">Rafn Benediktsson</name><affiliation wicri:level="1"><nlm:aff id="A62">Faculty of Medicine, University of Iceland, Reykjavík, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>Faculty of Medicine, University of Iceland, Reykjavík</wicri:regionArea><wicri:noRegion>Reykjavík</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A63">Landspitali University Hospital, Reykjavík, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>Landspitali University Hospital, Reykjavík</wicri:regionArea><wicri:noRegion>Reykjavík</wicri:noRegion></affiliation></author><author><name sortKey="Bonnycastle, Lori L" sort="Bonnycastle, Lori L" uniqKey="Bonnycastle L" first="Lori L" last="Bonnycastle">Lori L. Bonnycastle</name><affiliation wicri:level="2"><nlm:aff id="A50">National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Burtt, Noel" sort="Burtt, Noel" uniqKey="Burtt N" first="Noël" last="Burtt">Noël Burtt</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Carey, Jason" sort="Carey, Jason" uniqKey="Carey J" first="Jason" last="Carey">Jason Carey</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Charpentier, Guillaume" sort="Charpentier, Guillaume" uniqKey="Charpentier G" first="Guillaume" last="Charpentier">Guillaume Charpentier</name><affiliation wicri:level="1"><nlm:aff id="A64">Endocrinology-Diabetology Unit, Corbeil-Essonnes Hospital, Corbeil-Essonnes, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Endocrinology-Diabetology Unit, Corbeil-Essonnes Hospital, Corbeil-Essonnes</wicri:regionArea><wicri:noRegion>Corbeil-Essonnes</wicri:noRegion><wicri:noRegion>Corbeil-Essonnes</wicri:noRegion></affiliation></author><author><name sortKey="Crenshaw, Andrew T" sort="Crenshaw, Andrew T" uniqKey="Crenshaw A" first="Andrew T" last="Crenshaw">Andrew T. Crenshaw</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Doney, Alex S F" sort="Doney, Alex S F" uniqKey="Doney A" first="Alex S F" last="Doney">Alex S F. Doney</name><affiliation wicri:level="1"><nlm:aff id="A65">Diabetes Research Centre, Biomedical Research Institute, University of Dundee, Ninewells Hospital, Dundee, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Diabetes Research Centre, Biomedical Research Institute, University of Dundee, Ninewells Hospital, Dundee</wicri:regionArea><wicri:noRegion>Dundee</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A66">Pharmacogenomics Centre, Biomedical Research Institute, University of Dundee, Ninewells Hospital, Dundee, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Pharmacogenomics Centre, Biomedical Research Institute, University of Dundee, Ninewells Hospital, Dundee</wicri:regionArea><wicri:noRegion>Dundee</wicri:noRegion></affiliation></author><author><name sortKey="Dorkhan, Mozhgan" sort="Dorkhan, Mozhgan" uniqKey="Dorkhan M" first="Mozhgan" last="Dorkhan">Mozhgan Dorkhan</name><affiliation wicri:level="1"><nlm:aff id="A60">Lund University Diabetes Centre, Department of Clinical Science Malmö, Scania University Hospital, Lund University, Malmö, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Lund University Diabetes Centre, Department of Clinical Science Malmö, Scania University Hospital, Lund University, Malmö</wicri:regionArea><wicri:noRegion>Malmö</wicri:noRegion></affiliation></author><author><name sortKey="Edkins, Sarah" sort="Edkins, Sarah" uniqKey="Edkins S" first="Sarah" last="Edkins">Sarah Edkins</name><affiliation wicri:level="1"><nlm:aff id="A19">Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Emilsson, Valur" sort="Emilsson, Valur" uniqKey="Emilsson V" first="Valur" last="Emilsson">Valur Emilsson</name><affiliation wicri:level="1"><nlm:aff id="A67">Icelandic Heart Association, Kopavogur, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea><wicri:noRegion>Kopavogur</wicri:noRegion></affiliation></author><author><name sortKey="Eury, Elodie" sort="Eury, Elodie" uniqKey="Eury E" first="Elodie" last="Eury">Elodie Eury</name><affiliation wicri:level="3"><nlm:aff id="A25">CNRS-UMR-8199, Institute of Biology and Lille 2 University, Pasteur Institute, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>CNRS-UMR-8199, Institute of Biology and Lille 2 University, Pasteur Institute, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation></author><author><name sortKey="Forsen, Tom" sort="Forsen, Tom" uniqKey="Forsen T" first="Tom" last="Forsen">Tom Forsen</name><affiliation wicri:level="4"><nlm:aff id="A68">Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Department of General Practice and Primary Health Care, University of Helsinki, Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A69">Vaasa Health Care Centre, Vaasa, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Vaasa Health Care Centre, Vaasa</wicri:regionArea><wicri:noRegion>Vaasa</wicri:noRegion></affiliation></author><author><name sortKey="Gertow, Karl" sort="Gertow, Karl" uniqKey="Gertow K" first="Karl" last="Gertow">Karl Gertow</name><affiliation wicri:level="3"><nlm:aff id="A8">Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A9">Center for Molecular Medicine, Karolinska University Hospital Solna, Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Center for Molecular Medicine, Karolinska University Hospital Solna, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Gigante, Bruna" sort="Gigante, Bruna" uniqKey="Gigante B" first="Bruna" last="Gigante">Bruna Gigante</name><affiliation wicri:level="3"><nlm:aff id="A70">Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Grant, George B" sort="Grant, George B" uniqKey="Grant G" first="George B" last="Grant">George B. Grant</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Groves, Christopher J" sort="Groves, Christopher J" uniqKey="Groves C" first="Christopher J" last="Groves">Christopher J. Groves</name><affiliation wicri:level="4"><nlm:aff id="A12">Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Guiducci, Candace" sort="Guiducci, Candace" uniqKey="Guiducci C" first="Candace" last="Guiducci">Candace Guiducci</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Herder, Christian" sort="Herder, Christian" uniqKey="Herder C" first="Christian" last="Herder">Christian Herder</name><affiliation wicri:level="3"><nlm:aff id="A71">Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Düsseldorf</region><settlement type="city">Düsseldorf</settlement></placeName></affiliation></author><author><name sortKey="Hreidarsson, Astradur B" sort="Hreidarsson, Astradur B" uniqKey="Hreidarsson A" first="Astradur B" last="Hreidarsson">Astradur B. Hreidarsson</name><affiliation wicri:level="1"><nlm:aff id="A63">Landspitali University Hospital, Reykjavík, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>Landspitali University Hospital, Reykjavík</wicri:regionArea><wicri:noRegion>Reykjavík</wicri:noRegion></affiliation></author><author><name sortKey="Hui, Jennie" sort="Hui, Jennie" uniqKey="Hui J" first="Jennie" last="Hui">Jennie Hui</name><affiliation wicri:level="1"><nlm:aff id="A72">Busselton Population Medical Research Institute, Sir Charles Gairdner Hospital, Nedlands, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>Busselton Population Medical Research Institute, Sir Charles Gairdner Hospital, Nedlands</wicri:regionArea><wicri:noRegion>Nedlands</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A73">PathWest Laboratory Medicine of Western Australia, QEII Medical Centre, Nedlands, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>PathWest Laboratory Medicine of Western Australia, QEII Medical Centre, Nedlands</wicri:regionArea><wicri:noRegion>Nedlands</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A74">School of Pathology and Laboratory Medicine, The University of Western Australia, Nedlands, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>School of Pathology and Laboratory Medicine, The University of Western Australia, Nedlands</wicri:regionArea><wicri:noRegion>Nedlands</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A75">School of Population Health, The University of Western Australia, Nedlands, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>School of Population Health, The University of Western Australia, Nedlands</wicri:regionArea><wicri:noRegion>Nedlands</wicri:noRegion></affiliation></author><author><name sortKey="James, Alan" sort="James, Alan" uniqKey="James A" first="Alan" last="James">Alan James</name><affiliation wicri:level="1"><nlm:aff id="A72">Busselton Population Medical Research Institute, Sir Charles Gairdner Hospital, Nedlands, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>Busselton Population Medical Research Institute, Sir Charles Gairdner Hospital, Nedlands</wicri:regionArea><wicri:noRegion>Nedlands</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A76">Department of Pulmonary Physiology and Sleep Medicine, West Australian Sleep Disorders Research Institute, Queen Elizabeth II Medical Centre, Hospital Avenue, Nedlands, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>Department of Pulmonary Physiology and Sleep Medicine, West Australian Sleep Disorders Research Institute, Queen Elizabeth II Medical Centre, Hospital Avenue, Nedlands</wicri:regionArea><wicri:noRegion>Nedlands</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A77">School of Medicine and Pharmacology, University of Western Australia, Nedlands, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>School of Medicine and Pharmacology, University of Western Australia, Nedlands</wicri:regionArea><wicri:noRegion>Nedlands</wicri:noRegion></affiliation></author><author><name sortKey="Jonsson, Anna" sort="Jonsson, Anna" uniqKey="Jonsson A" first="Anna" last="Jonsson">Anna Jonsson</name><affiliation wicri:level="1"><nlm:aff id="A60">Lund University Diabetes Centre, Department of Clinical Science Malmö, Scania University Hospital, Lund University, Malmö, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Lund University Diabetes Centre, Department of Clinical Science Malmö, Scania University Hospital, Lund University, Malmö</wicri:regionArea><wicri:noRegion>Malmö</wicri:noRegion></affiliation></author><author><name sortKey="Rathmann, Wolfgang" sort="Rathmann, Wolfgang" uniqKey="Rathmann W" first="Wolfgang" last="Rathmann">Wolfgang Rathmann</name><affiliation wicri:level="3"><nlm:aff id="A78">Institute of Biometrics and Epidemiology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Institute of Biometrics and Epidemiology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Düsseldorf</region><settlement type="city">Düsseldorf</settlement></placeName></affiliation></author><author><name sortKey="Klopp, Norman" sort="Klopp, Norman" uniqKey="Klopp N" first="Norman" last="Klopp">Norman Klopp</name><affiliation wicri:level="1"><nlm:aff id="A11">Research Unit of Molecular Epidemiology, Helmholtz Zentrum Muenchen, Neuherberg, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Research Unit of Molecular Epidemiology, Helmholtz Zentrum Muenchen, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Kravic, Jasmina" sort="Kravic, Jasmina" uniqKey="Kravic J" first="Jasmina" last="Kravic">Jasmina Kravic</name><affiliation wicri:level="1"><nlm:aff id="A60">Lund University Diabetes Centre, Department of Clinical Science Malmö, Scania University Hospital, Lund University, Malmö, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Lund University Diabetes Centre, Department of Clinical Science Malmö, Scania University Hospital, Lund University, Malmö</wicri:regionArea><wicri:noRegion>Malmö</wicri:noRegion></affiliation></author><author><name sortKey="Krjutskov, Kaarel" sort="Krjutskov, Kaarel" uniqKey="Krjutskov K" first="Kaarel" last="Krjutškov">Kaarel Krjutškov</name><affiliation wicri:level="1"><nlm:aff id="A16">Estonian Genome Center, University of Tartu, Tartu, Estonia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Estonie</country><wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation></author><author><name sortKey="Langford, Cordelia" sort="Langford, Cordelia" uniqKey="Langford C" first="Cordelia" last="Langford">Cordelia Langford</name><affiliation wicri:level="1"><nlm:aff id="A19">Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Leander, Karin" sort="Leander, Karin" uniqKey="Leander K" first="Karin" last="Leander">Karin Leander</name><affiliation wicri:level="3"><nlm:aff id="A70">Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Lindholm, Eero" sort="Lindholm, Eero" uniqKey="Lindholm E" first="Eero" last="Lindholm">Eero Lindholm</name><affiliation wicri:level="1"><nlm:aff id="A60">Lund University Diabetes Centre, Department of Clinical Science Malmö, Scania University Hospital, Lund University, Malmö, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Lund University Diabetes Centre, Department of Clinical Science Malmö, Scania University Hospital, Lund University, Malmö</wicri:regionArea><wicri:noRegion>Malmö</wicri:noRegion></affiliation></author><author><name sortKey="Lobbens, Stephane" sort="Lobbens, Stephane" uniqKey="Lobbens S" first="Stéphane" last="Lobbens">Stéphane Lobbens</name><affiliation wicri:level="3"><nlm:aff id="A25">CNRS-UMR-8199, Institute of Biology and Lille 2 University, Pasteur Institute, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>CNRS-UMR-8199, Institute of Biology and Lille 2 University, Pasteur Institute, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation></author><author><name sortKey="M Nnisto, Satu" sort="M Nnisto, Satu" uniqKey="M Nnisto S" first="Satu" last="M Nnistö">Satu M Nnistö</name><affiliation wicri:level="1"><nlm:aff id="A59">Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Mirza, Ghazala" sort="Mirza, Ghazala" uniqKey="Mirza G" first="Ghazala" last="Mirza">Ghazala Mirza</name><affiliation wicri:level="4"><nlm:aff id="A1">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Muhleisen, Thomas W" sort="Muhleisen, Thomas W" uniqKey="Muhleisen T" first="Thomas W" last="Mühleisen">Thomas W. Mühleisen</name><affiliation wicri:level="3"><nlm:aff id="A79">Institute of Human Genetics, University of Bonn, Bonn, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Institute of Human Genetics, University of Bonn, Bonn</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Cologne</region><settlement type="city">Bonn</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A80">Department of Genomics, Life & Brain Center, University of Bonn, Bonn, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Department of Genomics, Life & Brain Center, University of Bonn, Bonn</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Cologne</region><settlement type="city">Bonn</settlement></placeName></affiliation></author><author><name sortKey="Musk, Bill" sort="Musk, Bill" uniqKey="Musk B" first="Bill" last="Musk">Bill Musk</name><affiliation wicri:level="1"><nlm:aff id="A72">Busselton Population Medical Research Institute, Sir Charles Gairdner Hospital, Nedlands, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>Busselton Population Medical Research Institute, Sir Charles Gairdner Hospital, Nedlands</wicri:regionArea><wicri:noRegion>Nedlands</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A75">School of Population Health, The University of Western Australia, Nedlands, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>School of Population Health, The University of Western Australia, Nedlands</wicri:regionArea><wicri:noRegion>Nedlands</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A77">School of Medicine and Pharmacology, University of Western Australia, Nedlands, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>School of Medicine and Pharmacology, University of Western Australia, Nedlands</wicri:regionArea><wicri:noRegion>Nedlands</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A81">Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands</wicri:regionArea><wicri:noRegion>Nedlands</wicri:noRegion></affiliation></author><author><name sortKey="Parkin, Melissa" sort="Parkin, Melissa" uniqKey="Parkin M" first="Melissa" last="Parkin">Melissa Parkin</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Rallidis, Loukianos" sort="Rallidis, Loukianos" uniqKey="Rallidis L" first="Loukianos" last="Rallidis">Loukianos Rallidis</name><affiliation wicri:level="3"><nlm:aff id="A82">University General Hospital Attikon, Athens, Greece.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Grèce</country><wicri:regionArea>University General Hospital Attikon, Athens</wicri:regionArea><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region></placeName></affiliation></author><author><name sortKey="Saramies, Jouko" sort="Saramies, Jouko" uniqKey="Saramies J" first="Jouko" last="Saramies">Jouko Saramies</name><affiliation wicri:level="1"><nlm:aff id="A83">South Karelia Central Hospital, Lappeenranta, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>South Karelia Central Hospital, Lappeenranta</wicri:regionArea><wicri:noRegion>Lappeenranta</wicri:noRegion></affiliation></author><author><name sortKey="Sennblad, Bengt" sort="Sennblad, Bengt" uniqKey="Sennblad B" first="Bengt" last="Sennblad">Bengt Sennblad</name><affiliation wicri:level="3"><nlm:aff id="A8">Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A9">Center for Molecular Medicine, Karolinska University Hospital Solna, Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Center for Molecular Medicine, Karolinska University Hospital Solna, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Shah, Sonia" sort="Shah, Sonia" uniqKey="Shah S" first="Sonia" last="Shah">Sonia Shah</name><affiliation wicri:level="4"><nlm:aff id="A84">UCL Genetics Institute, Department of Genetics, Evolution and Environment, University College London, London, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>UCL Genetics Institute, Department of Genetics, Evolution and Environment, University College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">University College de Londres</orgName></affiliation></author><author><name sortKey="Sigur Sson, Gunnar" sort="Sigur Sson, Gunnar" uniqKey="Sigur Sson G" first="Gunnar" last="Sigur Sson">Gunnar Sigur Sson</name><affiliation wicri:level="1"><nlm:aff id="A63">Landspitali University Hospital, Reykjavík, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>Landspitali University Hospital, Reykjavík</wicri:regionArea><wicri:noRegion>Reykjavík</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A67">Icelandic Heart Association, Kopavogur, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea><wicri:noRegion>Kopavogur</wicri:noRegion></affiliation></author><author><name sortKey="Silveira, Angela" sort="Silveira, Angela" uniqKey="Silveira A" first="Angela" last="Silveira">Angela Silveira</name><affiliation wicri:level="3"><nlm:aff id="A8">Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A9">Center for Molecular Medicine, Karolinska University Hospital Solna, Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Center for Molecular Medicine, Karolinska University Hospital Solna, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Steinbach, Gerald" sort="Steinbach, Gerald" uniqKey="Steinbach G" first="Gerald" last="Steinbach">Gerald Steinbach</name><affiliation wicri:level="4"><nlm:aff id="A85">Department of Clinical Chemistry and Central Laboratory, University of Ulm, Ulm, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Department of Clinical Chemistry and Central Laboratory, University of Ulm, Ulm</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Ulm</settlement><settlement type="city">Ulm</settlement></placeName><orgName type="university">Université d'Ulm</orgName></affiliation></author><author><name sortKey="Thorand, Barbara" sort="Thorand, Barbara" uniqKey="Thorand B" first="Barbara" last="Thorand">Barbara Thorand</name><affiliation wicri:level="1"><nlm:aff id="A86">Institute of Epidemiology II, Helmholtz Zentrum Muenchen, Neuherberg, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Institute of Epidemiology II, Helmholtz Zentrum Muenchen, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Trakalo, Joseph" sort="Trakalo, Joseph" uniqKey="Trakalo J" first="Joseph" last="Trakalo">Joseph Trakalo</name><affiliation wicri:level="4"><nlm:aff id="A1">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Veglia, Fabrizio" sort="Veglia, Fabrizio" uniqKey="Veglia F" first="Fabrizio" last="Veglia">Fabrizio Veglia</name><affiliation wicri:level="3"><nlm:aff id="A87">Centro Cardiologico Monzino, IRCCS, Milan, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Centro Cardiologico Monzino, IRCCS, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Wennauer, Roman" sort="Wennauer, Roman" uniqKey="Wennauer R" first="Roman" last="Wennauer">Roman Wennauer</name><affiliation wicri:level="4"><nlm:aff id="A85">Department of Clinical Chemistry and Central Laboratory, University of Ulm, Ulm, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Department of Clinical Chemistry and Central Laboratory, University of Ulm, Ulm</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Ulm</settlement><settlement type="city">Ulm</settlement></placeName><orgName type="university">Université d'Ulm</orgName></affiliation></author><author><name sortKey="Winckler, Wendy" sort="Winckler, Wendy" uniqKey="Winckler W" first="Wendy" last="Winckler">Wendy Winckler</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Zabaneh, Delilah" sort="Zabaneh, Delilah" uniqKey="Zabaneh D" first="Delilah" last="Zabaneh">Delilah Zabaneh</name><affiliation wicri:level="4"><nlm:aff id="A84">UCL Genetics Institute, Department of Genetics, Evolution and Environment, University College London, London, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>UCL Genetics Institute, Department of Genetics, Evolution and Environment, University College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">University College de Londres</orgName></affiliation></author><author><name sortKey="Campbell, Harry" sort="Campbell, Harry" uniqKey="Campbell H" first="Harry" last="Campbell">Harry Campbell</name><affiliation wicri:level="4"><nlm:aff id="A18">Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A88">MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Western General Hospital, Edinburgh, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Western General Hospital, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Van Duijn, Cornelia" sort="Van Duijn, Cornelia" uniqKey="Van Duijn C" first="Cornelia" last="Van Duijn">Cornelia Van Duijn</name><affiliation wicri:level="3"><nlm:aff id="A89">Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A90">Netherland Genomics Initiative, Netherlands Consortium for Healthy Ageing and Centre for Medical Systems Biology, Rotterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Netherland Genomics Initiative, Netherlands Consortium for Healthy Ageing and Centre for Medical Systems Biology, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Uitterlinden89, Andre G" sort="Uitterlinden89, Andre G" uniqKey="Uitterlinden89 A" first="Andre G" last="Uitterlinden89-">Andre G. Uitterlinden89-</name><affiliation wicri:level="3"><nlm:aff id="A89">Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A90">Netherland Genomics Initiative, Netherlands Consortium for Healthy Ageing and Centre for Medical Systems Biology, Rotterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Netherland Genomics Initiative, Netherlands Consortium for Healthy Ageing and Centre for Medical Systems Biology, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A91">Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name><affiliation wicri:level="3"><nlm:aff id="A89">Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Sijbrands, Eric" sort="Sijbrands, Eric" uniqKey="Sijbrands E" first="Eric" last="Sijbrands">Eric Sijbrands</name><affiliation wicri:level="3"><nlm:aff id="A91">Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Abecasis, Goncalo R" sort="Abecasis, Goncalo R" uniqKey="Abecasis G" first="Goncalo R" last="Abecasis">Goncalo R. Abecasis</name><affiliation wicri:level="2"><nlm:aff id="A4">Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Biostatistics, University of Michigan, Ann Arbor, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Owen, Katharine R" sort="Owen, Katharine R" uniqKey="Owen K" first="Katharine R" last="Owen">Katharine R. Owen</name><affiliation wicri:level="4"><nlm:aff id="A12">Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A92">Oxford National Institute for Health Research Biomedical Research Centre, Churchill Hospital, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Oxford National Institute for Health Research Biomedical Research Centre, Churchill Hospital, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="Zeggini, Eleftheria" sort="Zeggini, Eleftheria" uniqKey="Zeggini E" first="Eleftheria" last="Zeggini">Eleftheria Zeggini</name><affiliation wicri:level="1"><nlm:aff id="A19">Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Trip, Mieke D" sort="Trip, Mieke D" uniqKey="Trip M" first="Mieke D" last="Trip">Mieke D. Trip</name><affiliation wicri:level="4"><nlm:aff id="A56">Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region><settlement type="city">Amsterdam</settlement></placeName><orgName type="university">Université d'Amsterdam</orgName></affiliation></author><author><name sortKey="Forouhi, Nita G" sort="Forouhi, Nita G" uniqKey="Forouhi N" first="Nita G" last="Forouhi">Nita G. Forouhi</name><affiliation wicri:level="1"><nlm:aff id="A20">MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Syv Nen, Ann Christine" sort="Syv Nen, Ann Christine" uniqKey="Syv Nen A" first="Ann-Christine" last="Syv Nen">Ann-Christine Syv Nen</name><affiliation wicri:level="4"><nlm:aff id="A93">Molecular Medicine, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Molecular Medicine, Department of Medical Sciences, Uppsala University, Uppsala</wicri:regionArea><orgName type="university">Université d'Uppsala</orgName><placeName><settlement type="city">Uppsala</settlement><region nuts="1">Svealand</region><region nuts="1">East Middle Sweden</region></placeName></affiliation></author><author><name sortKey="Eriksson, Johan G" sort="Eriksson, Johan G" uniqKey="Eriksson J" first="Johan G" last="Eriksson">Johan G. Eriksson</name><affiliation wicri:level="1"><nlm:aff id="A59">Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:aff id="A68">Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Department of General Practice and Primary Health Care, University of Helsinki, Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A94">Unit of General Practice, Helsinki University General Hospital, Helsinki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Unit of General Practice, Helsinki University General Hospital, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A95">Folkhälsan Research Center, Helsinki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Folkhälsan Research Center, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Peltonen, Leena" sort="Peltonen, Leena" uniqKey="Peltonen L" first="Leena" last="Peltonen">Leena Peltonen</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A19">Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A58">Institute for Molecular Medicine Finland (FIMM), Helsinki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Institute for Molecular Medicine Finland (FIMM), Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A59">Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Nothen, Markus M" sort="Nothen, Markus M" uniqKey="Nothen M" first="Markus M" last="Nöthen">Markus M. Nöthen</name><affiliation wicri:level="3"><nlm:aff id="A79">Institute of Human Genetics, University of Bonn, Bonn, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Institute of Human Genetics, University of Bonn, Bonn</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Cologne</region><settlement type="city">Bonn</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A80">Department of Genomics, Life & Brain Center, University of Bonn, Bonn, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Department of Genomics, Life & Brain Center, University of Bonn, Bonn</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Cologne</region><settlement type="city">Bonn</settlement></placeName></affiliation></author><author><name sortKey="Balkau, Beverley" sort="Balkau, Beverley" uniqKey="Balkau B" first="Beverley" last="Balkau">Beverley Balkau</name><affiliation wicri:level="1"><nlm:aff id="A96">INSERM CESP U1018, Villejuif, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>INSERM CESP U1018, Villejuif</wicri:regionArea><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A97">University Paris Sud 11, UMRS 1018, Villejuif, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>University Paris Sud 11, UMRS 1018, Villejuif</wicri:regionArea><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation></author><author><name sortKey="Palmer, Colin N A" sort="Palmer, Colin N A" uniqKey="Palmer C" first="Colin N A" last="Palmer">Colin N A. Palmer</name><affiliation wicri:level="1"><nlm:aff id="A65">Diabetes Research Centre, Biomedical Research Institute, University of Dundee, Ninewells Hospital, Dundee, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Diabetes Research Centre, Biomedical Research Institute, University of Dundee, Ninewells Hospital, Dundee</wicri:regionArea><wicri:noRegion>Dundee</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A66">Pharmacogenomics Centre, Biomedical Research Institute, University of Dundee, Ninewells Hospital, Dundee, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Pharmacogenomics Centre, Biomedical Research Institute, University of Dundee, Ninewells Hospital, Dundee</wicri:regionArea><wicri:noRegion>Dundee</wicri:noRegion></affiliation></author><author><name sortKey="Lyssenko, Valeriya" sort="Lyssenko, Valeriya" uniqKey="Lyssenko V" first="Valeriya" last="Lyssenko">Valeriya Lyssenko</name><affiliation wicri:level="1"><nlm:aff id="A60">Lund University Diabetes Centre, Department of Clinical Science Malmö, Scania University Hospital, Lund University, Malmö, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Lund University Diabetes Centre, Department of Clinical Science Malmö, Scania University Hospital, Lund University, Malmö</wicri:regionArea><wicri:noRegion>Malmö</wicri:noRegion></affiliation></author><author><name sortKey="Tuomi, Tiinamaija" sort="Tuomi, Tiinamaija" uniqKey="Tuomi T" first="Tiinamaija" last="Tuomi">Tiinamaija Tuomi</name><affiliation wicri:level="1"><nlm:aff id="A95">Folkhälsan Research Center, Helsinki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Folkhälsan Research Center, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A98">Department of Medicine, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Department of Medicine, Helsinki University Hospital, University of Helsinki, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Isomaa, Bo" sort="Isomaa, Bo" uniqKey="Isomaa B" first="Bo" last="Isomaa">Bo Isomaa</name><affiliation wicri:level="1"><nlm:aff id="A95">Folkhälsan Research Center, Helsinki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Folkhälsan Research Center, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A99">Department of Social Services and Health Care, Jakobstad, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Department of Social Services and Health Care, Jakobstad</wicri:regionArea><wicri:noRegion>Jakobstad</wicri:noRegion></affiliation></author><author><name sortKey="Hunter, David J" sort="Hunter, David J" uniqKey="Hunter D" first="David J" last="Hunter">David J. Hunter</name><affiliation wicri:level="2"><nlm:aff id="A46">Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A47">Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A48">Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Qi, Lu" sort="Qi, Lu" uniqKey="Qi L" first="Lu" last="Qi">Lu Qi</name><affiliation wicri:level="2"><nlm:aff id="A46">Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A48">Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Shuldiner, Alan R" sort="Shuldiner, Alan R" uniqKey="Shuldiner A" first="Alan R" last="Shuldiner">Alan R. Shuldiner</name><affiliation wicri:level="2"><nlm:aff id="A100">Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A101">Geriatric Research Education and Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, Maryland, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Geriatric Research Education and Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A102">Program in Personalised and Genomic Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Program in Personalised and Genomic Medicine, University of Maryland School of Medicine, Baltimore, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Roden, Michael" sort="Roden, Michael" uniqKey="Roden M" first="Michael" last="Roden">Michael Roden</name><affiliation wicri:level="3"><nlm:aff id="A71">Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Düsseldorf</region><settlement type="city">Düsseldorf</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A103">Department of Medicine/Metabolic Diseases, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Department of Medicine/Metabolic Diseases, Heinrich Heine University Düsseldorf, Düsseldorf</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Düsseldorf</region><settlement type="city">Düsseldorf</settlement></placeName></affiliation></author><author><name sortKey="Barroso, Ines" sort="Barroso, Ines" uniqKey="Barroso I" first="Ines" last="Barroso">Ines Barroso</name><affiliation wicri:level="1"><nlm:aff id="A19">Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A104">University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A105">NIHR Cambridge Biomedical Research Centre, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>NIHR Cambridge Biomedical Research Centre, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Wilsgaard, Tom" sort="Wilsgaard, Tom" uniqKey="Wilsgaard T" first="Tom" last="Wilsgaard">Tom Wilsgaard</name><affiliation wicri:level="1"><nlm:aff id="A106">Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Norvège</country><wicri:regionArea>Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø</wicri:regionArea><wicri:noRegion>Tromsø</wicri:noRegion></affiliation></author><author><name sortKey="Beilby, John" sort="Beilby, John" uniqKey="Beilby J" first="John" last="Beilby">John Beilby</name><affiliation wicri:level="1"><nlm:aff id="A72">Busselton Population Medical Research Institute, Sir Charles Gairdner Hospital, Nedlands, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>Busselton Population Medical Research Institute, Sir Charles Gairdner Hospital, Nedlands</wicri:regionArea><wicri:noRegion>Nedlands</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A73">PathWest Laboratory Medicine of Western Australia, QEII Medical Centre, Nedlands, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>PathWest Laboratory Medicine of Western Australia, QEII Medical Centre, Nedlands</wicri:regionArea><wicri:noRegion>Nedlands</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A74">School of Pathology and Laboratory Medicine, The University of Western Australia, Nedlands, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>School of Pathology and Laboratory Medicine, The University of Western Australia, Nedlands</wicri:regionArea><wicri:noRegion>Nedlands</wicri:noRegion></affiliation></author><author><name sortKey="Hovingh, Kees" sort="Hovingh, Kees" uniqKey="Hovingh K" first="Kees" last="Hovingh">Kees Hovingh</name><affiliation wicri:level="4"><nlm:aff id="A56">Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region><settlement type="city">Amsterdam</settlement></placeName><orgName type="university">Université d'Amsterdam</orgName></affiliation></author><author><name sortKey="Price, Jackie F" sort="Price, Jackie F" uniqKey="Price J" first="Jackie F" last="Price">Jackie F. Price</name><affiliation wicri:level="4"><nlm:aff id="A18">Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Wilson, James F" sort="Wilson, James F" uniqKey="Wilson J" first="James F" last="Wilson">James F. Wilson</name><affiliation wicri:level="4"><nlm:aff id="A18">Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A88">MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Western General Hospital, Edinburgh, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Western General Hospital, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Rauramaa, Rainer" sort="Rauramaa, Rainer" uniqKey="Rauramaa R" first="Rainer" last="Rauramaa">Rainer Rauramaa</name><affiliation wicri:level="1"><nlm:aff id="A107">Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Kuopio Research Institute of Exercise Medicine, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A108">Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation></author><author><name sortKey="Lakka, Timo A" sort="Lakka, Timo A" uniqKey="Lakka T" first="Timo A" last="Lakka">Timo A. Lakka</name><affiliation wicri:level="1"><nlm:aff id="A61">Institute of Biomedicine, Physiology, University of Eastern Finland, Kuopio Campus, Kuopio, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Institute of Biomedicine, Physiology, University of Eastern Finland, Kuopio Campus, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A107">Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Kuopio Research Institute of Exercise Medicine, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation></author><author><name sortKey="Lind, Lars" sort="Lind, Lars" uniqKey="Lind L" first="Lars" last="Lind">Lars Lind</name><affiliation wicri:level="4"><nlm:aff id="A109">Department of Medical Sciences, Uppsala University, Akademiska Sjukhuset, Uppsala, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Department of Medical Sciences, Uppsala University, Akademiska Sjukhuset, Uppsala</wicri:regionArea><orgName type="university">Université d'Uppsala</orgName><placeName><settlement type="city">Uppsala</settlement><region nuts="1">Svealand</region><region nuts="1">East Middle Sweden</region></placeName></affiliation></author><author><name sortKey="Dedoussis, George" sort="Dedoussis, George" uniqKey="Dedoussis G" first="George" last="Dedoussis">George Dedoussis</name><affiliation wicri:level="4"><nlm:aff id="A110">Department of Dietetics-Nutrition, Harokopio University, Athens, Greece.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Grèce</country><wicri:regionArea>Department of Dietetics-Nutrition, Harokopio University, Athens</wicri:regionArea><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region><settlement type="city">Athènes</settlement></placeName><orgName type="university">Université Harokopio</orgName></affiliation></author><author><name sortKey="Nj Lstad, Inger" sort="Nj Lstad, Inger" uniqKey="Nj Lstad I" first="Inger" last="Nj Lstad">Inger Nj Lstad</name><affiliation wicri:level="1"><nlm:aff id="A106">Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Norvège</country><wicri:regionArea>Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø</wicri:regionArea><wicri:noRegion>Tromsø</wicri:noRegion></affiliation></author><author><name sortKey="Pedersen, Nancy L" sort="Pedersen, Nancy L" uniqKey="Pedersen N" first="Nancy L" last="Pedersen">Nancy L. Pedersen</name><affiliation wicri:level="3"><nlm:aff id="A55">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Khaw, Kay Tee" sort="Khaw, Kay Tee" uniqKey="Khaw K" first="Kay-Tee" last="Khaw">Kay-Tee Khaw</name><affiliation wicri:level="4"><nlm:aff id="A10">Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Wareham, Nicholas J" sort="Wareham, Nicholas J" uniqKey="Wareham N" first="Nicholas J" last="Wareham">Nicholas J. Wareham</name><affiliation wicri:level="1"><nlm:aff id="A20">MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Keinanen Kiukaanniemi, Sirkka M" sort="Keinanen Kiukaanniemi, Sirkka M" uniqKey="Keinanen Kiukaanniemi S" first="Sirkka M" last="Keinanen-Kiukaanniemi">Sirkka M. Keinanen-Kiukaanniemi</name><affiliation wicri:level="1"><nlm:aff id="A111">Faculty of Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Faculty of Medicine, Institute of Health Sciences, University of Oulu, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A112">Unit of General Practice, Oulu University Hospital, Oulu, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Unit of General Practice, Oulu University Hospital, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation></author><author><name sortKey="Saaristo, Timo E" sort="Saaristo, Timo E" uniqKey="Saaristo T" first="Timo E" last="Saaristo">Timo E. Saaristo</name><affiliation wicri:level="1"><nlm:aff id="A113">Finnish Diabetes Association, Tampere, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Finnish Diabetes Association, Tampere</wicri:regionArea><wicri:noRegion>Tampere</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A114">Pirkanmaa Hospital District, Tampere, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Pirkanmaa Hospital District, Tampere</wicri:regionArea><wicri:noRegion>Tampere</wicri:noRegion></affiliation></author><author><name sortKey="Korpi Hyov Lti, Eeva" sort="Korpi Hyov Lti, Eeva" uniqKey="Korpi Hyov Lti E" first="Eeva" last="Korpi-Hyöv Lti">Eeva Korpi-Hyöv Lti</name><affiliation wicri:level="1"><nlm:aff id="A115">South Ostrobothnia Central Hospital, Seinäjoki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>South Ostrobothnia Central Hospital, Seinäjoki</wicri:regionArea><wicri:noRegion>Seinäjoki</wicri:noRegion></affiliation></author><author><name sortKey="Saltevo, Juha" sort="Saltevo, Juha" uniqKey="Saltevo J" first="Juha" last="Saltevo">Juha Saltevo</name><affiliation wicri:level="1"><nlm:aff id="A116">Department of Medicine, Central Finland Central Hospital, Jyväskylä, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Department of Medicine, Central Finland Central Hospital, Jyväskylä</wicri:regionArea><wicri:noRegion>Jyväskylä</wicri:noRegion></affiliation></author><author><name sortKey="Laakso, Markku" sort="Laakso, Markku" uniqKey="Laakso M" first="Markku" last="Laakso">Markku Laakso</name><affiliation wicri:level="1"><nlm:aff id="A57">Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation></author><author><name sortKey="Kuusisto, Johanna" sort="Kuusisto, Johanna" uniqKey="Kuusisto J" first="Johanna" last="Kuusisto">Johanna Kuusisto</name><affiliation wicri:level="1"><nlm:aff id="A57">Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation></author><author><name sortKey="Metspalu, Andres" sort="Metspalu, Andres" uniqKey="Metspalu A" first="Andres" last="Metspalu">Andres Metspalu</name><affiliation wicri:level="1"><nlm:aff id="A16">Estonian Genome Center, University of Tartu, Tartu, Estonia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Estonie</country><wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A17">Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Estonie</country><wicri:regionArea>Institute of Molecular and Cell Biology, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation></author><author><name sortKey="Collins, Francis S" sort="Collins, Francis S" uniqKey="Collins F" first="Francis S" last="Collins">Francis S. Collins</name><affiliation wicri:level="2"><nlm:aff id="A50">National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Mohlke, Karen L" sort="Mohlke, Karen L" uniqKey="Mohlke K" first="Karen L" last="Mohlke">Karen L. Mohlke</name><affiliation wicri:level="2"><nlm:aff id="A117">Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Genetics, University of North Carolina, Chapel Hill, North Carolina</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Bergman, Richard N" sort="Bergman, Richard N" uniqKey="Bergman R" first="Richard N" last="Bergman">Richard N. Bergman</name><affiliation wicri:level="2"><nlm:aff id="A118">Diabetes and Obesity Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Diabetes and Obesity Research Institute, Cedars-Sinai Medical Center, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Tuomilehto, Jaakko" sort="Tuomilehto, Jaakko" uniqKey="Tuomilehto J" first="Jaakko" last="Tuomilehto">Jaakko Tuomilehto</name><affiliation wicri:level="1"><nlm:aff id="A27">Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A115">South Ostrobothnia Central Hospital, Seinäjoki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>South Ostrobothnia Central Hospital, Seinäjoki</wicri:regionArea><wicri:noRegion>Seinäjoki</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A119">Red RECAVA Grupo RD06/0014/0015, Hospital Universitario La Paz, Madrid, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Red RECAVA Grupo RD06/0014/0015, Hospital Universitario La Paz, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A120">Centre for Vascular Prevention, Danube-University Krems, Krems, Austria.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Autriche</country><wicri:regionArea>Centre for Vascular Prevention, Danube-University Krems, Krems</wicri:regionArea><wicri:noRegion>Krems</wicri:noRegion></affiliation></author><author><name sortKey="Boehm, Bernhard O" sort="Boehm, Bernhard O" uniqKey="Boehm B" first="Bernhard O" last="Boehm">Bernhard O. Boehm</name><affiliation wicri:level="3"><nlm:aff id="A121">Division of Endocrinology and Diabetes, Department of Internal Medicine, University Medical Centre Ulm, Ulm, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Division of Endocrinology and Diabetes, Department of Internal Medicine, University Medical Centre Ulm, Ulm</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Ulm</settlement></placeName></affiliation></author><author><name sortKey="Gieger, Christian" sort="Gieger, Christian" uniqKey="Gieger C" first="Christian" last="Gieger">Christian Gieger</name><affiliation wicri:level="1"><nlm:aff id="A22">Institute of Genetic Epidemiology, Helmholtz Zentrum Muenchen, Neuherberg, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum Muenchen, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Hveem, Kristian" sort="Hveem, Kristian" uniqKey="Hveem K" first="Kristian" last="Hveem">Kristian Hveem</name><affiliation wicri:level="1"><nlm:aff id="A51">HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Norvège</country><wicri:regionArea>HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger</wicri:regionArea><wicri:noRegion>Levanger</wicri:noRegion></affiliation></author><author><name sortKey="Cauchi, Stephane" sort="Cauchi, Stephane" uniqKey="Cauchi S" first="Stephane" last="Cauchi">Stephane Cauchi</name><affiliation wicri:level="3"><nlm:aff id="A25">CNRS-UMR-8199, Institute of Biology and Lille 2 University, Pasteur Institute, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>CNRS-UMR-8199, Institute of Biology and Lille 2 University, Pasteur Institute, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation></author><author><name sortKey="Froguel, Philippe" sort="Froguel, Philippe" uniqKey="Froguel P" first="Philippe" last="Froguel">Philippe Froguel</name><affiliation wicri:level="3"><nlm:aff id="A25">CNRS-UMR-8199, Institute of Biology and Lille 2 University, Pasteur Institute, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>CNRS-UMR-8199, Institute of Biology and Lille 2 University, Pasteur Institute, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A122">Genomic Medicine, Imperial College London, Hammersmith Hospital, London, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Genomic Medicine, Imperial College London, Hammersmith Hospital, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Baldassarre, Damiano" sort="Baldassarre, Damiano" uniqKey="Baldassarre D" first="Damiano" last="Baldassarre">Damiano Baldassarre</name><affiliation wicri:level="3"><nlm:aff id="A87">Centro Cardiologico Monzino, IRCCS, Milan, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Centro Cardiologico Monzino, IRCCS, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A123">Department of Pharmacological Sciences, University of Milan, Milan, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Department of Pharmacological Sciences, University of Milan, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Tremoli, Elena" sort="Tremoli, Elena" uniqKey="Tremoli E" first="Elena" last="Tremoli">Elena Tremoli</name><affiliation wicri:level="3"><nlm:aff id="A87">Centro Cardiologico Monzino, IRCCS, Milan, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Centro Cardiologico Monzino, IRCCS, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A123">Department of Pharmacological Sciences, University of Milan, Milan, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Department of Pharmacological Sciences, University of Milan, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Humphries, Steve E" sort="Humphries, Steve E" uniqKey="Humphries S" first="Steve E" last="Humphries">Steve E. Humphries</name><affiliation wicri:level="4"><nlm:aff id="A124">Institute of Cardiovascular Science, University College London, London, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Cardiovascular Science, University College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">University College de Londres</orgName></affiliation></author><author><name sortKey="Saleheen, Danish" sort="Saleheen, Danish" uniqKey="Saleheen D" first="Danish" last="Saleheen">Danish Saleheen</name><affiliation wicri:level="4"><nlm:aff id="A10">Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A125">Center for Non-Communicable Diseases Pakistan, Karachi, Pakistan.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pakistan</country><wicri:regionArea>Center for Non-Communicable Diseases Pakistan, Karachi</wicri:regionArea><wicri:noRegion>Karachi</wicri:noRegion></affiliation></author><author><name sortKey="Danesh, John" sort="Danesh, John" uniqKey="Danesh J" first="John" last="Danesh">John Danesh</name><affiliation wicri:level="4"><nlm:aff id="A10">Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Ingelsson, Erik" sort="Ingelsson, Erik" uniqKey="Ingelsson E" first="Erik" last="Ingelsson">Erik Ingelsson</name><affiliation wicri:level="3"><nlm:aff id="A55">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Ripatti, Samuli" sort="Ripatti, Samuli" uniqKey="Ripatti S" first="Samuli" last="Ripatti">Samuli Ripatti</name><affiliation wicri:level="1"><nlm:aff id="A19">Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A58">Institute for Molecular Medicine Finland (FIMM), Helsinki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Institute for Molecular Medicine Finland (FIMM), Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A59">Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Salomaa, Veikko" sort="Salomaa, Veikko" uniqKey="Salomaa V" first="Veikko" last="Salomaa">Veikko Salomaa</name><affiliation wicri:level="1"><nlm:aff id="A59">Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Erbel, Raimund" sort="Erbel, Raimund" uniqKey="Erbel R" first="Raimund" last="Erbel">Raimund Erbel</name><affiliation wicri:level="1"><nlm:aff id="A126">Clinic of Cardiology, West German Heart Centre, University Hospital of Essen, University Duisburg-Essen, Essen, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Clinic of Cardiology, West German Heart Centre, University Hospital of Essen, University Duisburg-Essen, Essen</wicri:regionArea><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author><author><name sortKey="Jockel, Karl Heinz" sort="Jockel, Karl Heinz" uniqKey="Jockel K" first="Karl-Heinz" last="Jöckel">Karl-Heinz Jöckel</name><affiliation wicri:level="1"><nlm:aff id="A24">Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, University Duisburg-Essen, Essen, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, University Duisburg-Essen, Essen</wicri:regionArea><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author><author><name sortKey="Moebus, Susanne" sort="Moebus, Susanne" uniqKey="Moebus S" first="Susanne" last="Moebus">Susanne Moebus</name><affiliation wicri:level="1"><nlm:aff id="A24">Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, University Duisburg-Essen, Essen, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, University Duisburg-Essen, Essen</wicri:regionArea><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author><author><name sortKey="Peters, Annette" sort="Peters, Annette" uniqKey="Peters A" first="Annette" last="Peters">Annette Peters</name><affiliation wicri:level="1"><nlm:aff id="A86">Institute of Epidemiology II, Helmholtz Zentrum Muenchen, Neuherberg, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Institute of Epidemiology II, Helmholtz Zentrum Muenchen, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Illig, Thomas" sort="Illig, Thomas" uniqKey="Illig T" first="Thomas" last="Illig">Thomas Illig</name><affiliation wicri:level="1"><nlm:aff id="A11">Research Unit of Molecular Epidemiology, Helmholtz Zentrum Muenchen, Neuherberg, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Research Unit of Molecular Epidemiology, Helmholtz Zentrum Muenchen, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A127">Hannover Unified Biobank, Hannover Medical School, Hannover, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Hannover Unified Biobank, Hannover Medical School, Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="De Faire, Ulf" sort="De Faire, Ulf" uniqKey="De Faire U" first="Ulf" last="De Faire">Ulf De Faire</name><affiliation wicri:level="3"><nlm:aff id="A70">Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Hamsten, Anders" sort="Hamsten, Anders" uniqKey="Hamsten A" first="Anders" last="Hamsten">Anders Hamsten</name><affiliation wicri:level="3"><nlm:aff id="A8">Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A9">Center for Molecular Medicine, Karolinska University Hospital Solna, Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Center for Molecular Medicine, Karolinska University Hospital Solna, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Morris, Andrew D" sort="Morris, Andrew D" uniqKey="Morris A" first="Andrew D" last="Morris">Andrew D. Morris</name><affiliation wicri:level="1"><nlm:aff id="A65">Diabetes Research Centre, Biomedical Research Institute, University of Dundee, Ninewells Hospital, Dundee, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Diabetes Research Centre, Biomedical Research Institute, University of Dundee, Ninewells Hospital, Dundee</wicri:regionArea><wicri:noRegion>Dundee</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A66">Pharmacogenomics Centre, Biomedical Research Institute, University of Dundee, Ninewells Hospital, Dundee, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Pharmacogenomics Centre, Biomedical Research Institute, University of Dundee, Ninewells Hospital, Dundee</wicri:regionArea><wicri:noRegion>Dundee</wicri:noRegion></affiliation></author><author><name sortKey="Donnelly, Peter J" sort="Donnelly, Peter J" uniqKey="Donnelly P" first="Peter J" last="Donnelly">Peter J. Donnelly</name><affiliation wicri:level="4"><nlm:aff id="A1">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A128">Department of Statistics, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Department of Statistics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Frayling, Timothy M" sort="Frayling, Timothy M" uniqKey="Frayling T" first="Timothy M" last="Frayling">Timothy M. Frayling</name><affiliation wicri:level="1"><nlm:aff id="A53">Genetics of Complex Traits, Institute of Biomedical and Clinical Science, Peninsula Medical School, University of Exeter, Magdalen Road, Exeter, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Genetics of Complex Traits, Institute of Biomedical and Clinical Science, Peninsula Medical School, University of Exeter, Magdalen Road, Exeter</wicri:regionArea><wicri:noRegion>Exeter</wicri:noRegion></affiliation></author><author><name sortKey="Hattersley, Andrew T" sort="Hattersley, Andrew T" uniqKey="Hattersley A" first="Andrew T" last="Hattersley">Andrew T. Hattersley</name><affiliation wicri:level="1"><nlm:aff id="A129">Diabetes Genetics, Institute of Biomedical and Clinical Science, Peninsula Medical School, University of Exeter, Exeter, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Diabetes Genetics, Institute of Biomedical and Clinical Science, Peninsula Medical School, University of Exeter, Exeter</wicri:regionArea><wicri:noRegion>Exeter</wicri:noRegion></affiliation></author><author><name sortKey="Boerwinkle, Eric" sort="Boerwinkle, Eric" uniqKey="Boerwinkle E" first="Eric" last="Boerwinkle">Eric Boerwinkle</name><affiliation wicri:level="2"><nlm:aff id="A130">Human Genetics Center, University of Texas Health Science Center at Houston, Houston, Texas, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Human Genetics Center, University of Texas Health Science Center at Houston, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A131">Human Genome Sequencing Center at Baylor College of Medicine, Houston, Texas, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Human Genome Sequencing Center at Baylor College of Medicine, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Melander, Olle" sort="Melander, Olle" uniqKey="Melander O" first="Olle" last="Melander">Olle Melander</name><affiliation wicri:level="1"><nlm:aff id="A60">Lund University Diabetes Centre, Department of Clinical Science Malmö, Scania University Hospital, Lund University, Malmö, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Lund University Diabetes Centre, Department of Clinical Science Malmö, Scania University Hospital, Lund University, Malmö</wicri:regionArea><wicri:noRegion>Malmö</wicri:noRegion></affiliation></author><author><name sortKey="Kathiresan, Sekar" sort="Kathiresan, Sekar" uniqKey="Kathiresan S" first="Sekar" last="Kathiresan">Sekar Kathiresan</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A5">Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A132">Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Nilsson, Peter M" sort="Nilsson, Peter M" uniqKey="Nilsson P" first="Peter M" last="Nilsson">Peter M. Nilsson</name><affiliation wicri:level="1"><nlm:aff id="A60">Lund University Diabetes Centre, Department of Clinical Science Malmö, Scania University Hospital, Lund University, Malmö, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Lund University Diabetes Centre, Department of Clinical Science Malmö, Scania University Hospital, Lund University, Malmö</wicri:regionArea><wicri:noRegion>Malmö</wicri:noRegion></affiliation></author><author><name sortKey="Deloukas, Panos" sort="Deloukas, Panos" uniqKey="Deloukas P" first="Panos" last="Deloukas">Panos Deloukas</name><affiliation wicri:level="1"><nlm:aff id="A19">Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Thorsteinsdottir, Unnur" sort="Thorsteinsdottir, Unnur" uniqKey="Thorsteinsdottir U" first="Unnur" last="Thorsteinsdottir">Unnur Thorsteinsdottir</name><affiliation wicri:level="1"><nlm:aff id="A7">deCODE Genetics, Reykjavik, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>deCODE Genetics, Reykjavik</wicri:regionArea><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A62">Faculty of Medicine, University of Iceland, Reykjavík, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>Faculty of Medicine, University of Iceland, Reykjavík</wicri:regionArea><wicri:noRegion>Reykjavík</wicri:noRegion></affiliation></author><author><name sortKey="Groop, Leif C" sort="Groop, Leif C" uniqKey="Groop L" first="Leif C" last="Groop">Leif C. Groop</name><affiliation wicri:level="1"><nlm:aff id="A60">Lund University Diabetes Centre, Department of Clinical Science Malmö, Scania University Hospital, Lund University, Malmö, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Lund University Diabetes Centre, Department of Clinical Science Malmö, Scania University Hospital, Lund University, Malmö</wicri:regionArea><wicri:noRegion>Malmö</wicri:noRegion></affiliation></author><author><name sortKey="Stefansson, Kari" sort="Stefansson, Kari" uniqKey="Stefansson K" first="Kari" last="Stefansson">Kari Stefansson</name><affiliation wicri:level="1"><nlm:aff id="A7">deCODE Genetics, Reykjavik, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>deCODE Genetics, Reykjavik</wicri:regionArea><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A62">Faculty of Medicine, University of Iceland, Reykjavík, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>Faculty of Medicine, University of Iceland, Reykjavík</wicri:regionArea><wicri:noRegion>Reykjavík</wicri:noRegion></affiliation></author><author><name sortKey="Hu, Frank" sort="Hu, Frank" uniqKey="Hu F" first="Frank" last="Hu">Frank Hu</name><affiliation wicri:level="2"><nlm:aff id="A46">Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A48">Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Pankow, James S" sort="Pankow, James S" uniqKey="Pankow J" first="James S" last="Pankow">James S. Pankow</name><affiliation wicri:level="2"><nlm:aff id="A133">Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota</wicri:regionArea><placeName><region type="state">Minnesota</region></placeName></affiliation></author><author><name sortKey="Dupuis, Josee" sort="Dupuis, Josee" uniqKey="Dupuis J" first="Josée" last="Dupuis">Josée Dupuis</name><affiliation wicri:level="2"><nlm:aff id="A32">National Heart, Lung, and Blood Institute’s Framingham Heart Study, Framingham, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>National Heart, Lung, and Blood Institute’s Framingham Heart Study, Framingham, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A40">Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Meigs, James B" sort="Meigs, James B" uniqKey="Meigs J" first="James B" last="Meigs">James B. Meigs</name><affiliation wicri:level="2"><nlm:aff id="A6">Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Medicine, Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A134">General Medicine Division, Massachusetts General Hospital, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>General Medicine Division, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Altshuler, David" sort="Altshuler, David" uniqKey="Altshuler D" first="David" last="Altshuler">David Altshuler</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A5">Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A6">Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Medicine, Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A135">Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Genetics, Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A136">Department of Molecular Biology, Harvard Medical School, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Molecular Biology, Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A137">Diabetes Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Diabetes Unit, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Boehnke, Michael" sort="Boehnke, Michael" uniqKey="Boehnke M" first="Michael" last="Boehnke">Michael Boehnke</name><affiliation wicri:level="2"><nlm:aff id="A4">Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Biostatistics, University of Michigan, Ann Arbor, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Mccarthy, Mark I" sort="Mccarthy, Mark I" uniqKey="Mccarthy M" first="Mark I" last="Mccarthy">Mark I. Mccarthy</name><affiliation wicri:level="4"><nlm:aff id="A1">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A12">Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A92">Oxford National Institute for Health Research Biomedical Research Centre, Churchill Hospital, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Oxford National Institute for Health Research Biomedical Research Centre, Churchill Hospital, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">22885922</idno><idno type="pmc">3442244</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442244</idno><idno type="RBID">PMC:3442244</idno><idno type="doi">10.1038/ng.2383</idno><date when="2012">2012</date><idno type="wicri:Area/Pmc/Corpus">002E18</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002E18</idno><idno type="wicri:Area/Pmc/Curation">002C68</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">002C68</idno><idno type="wicri:Area/Pmc/Checkpoint">001E65</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">001E65</idno><idno type="wicri:Area/Ncbi/Merge">000F28</idno><idno type="wicri:Area/Ncbi/Curation">000F28</idno><idno type="wicri:Area/Ncbi/Checkpoint">000F28</idno><idno type="wicri:doubleKey">1061-4036:2012:Morris A:large:scale:association</idno><idno type="wicri:Area/Main/Merge">005552</idno><idno type="wicri:Area/Main/Curation">005329</idno><idno type="wicri:Area/Main/Exploration">005329</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes</title><author><name sortKey="Morris, Andrew P" sort="Morris, Andrew P" uniqKey="Morris A" first="Andrew P" last="Morris">Andrew P. Morris</name><affiliation wicri:level="4"><nlm:aff id="A1">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Voight, Benjamin F" sort="Voight, Benjamin F" uniqKey="Voight B" first="Benjamin F" last="Voight">Benjamin F. Voight</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A3">University of Pennsylvania - Perelman School of Medicine, Department of Pharmacology, Philadelphia, Pennsylvania, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>University of Pennsylvania - Perelman School of Medicine, Department of Pharmacology, Philadelphia, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Teslovich, Tanya M" sort="Teslovich, Tanya M" uniqKey="Teslovich T" first="Tanya M" last="Teslovich">Tanya M. Teslovich</name><affiliation wicri:level="2"><nlm:aff id="A4">Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Biostatistics, University of Michigan, Ann Arbor, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Ferreira, Teresa" sort="Ferreira, Teresa" uniqKey="Ferreira T" first="Teresa" last="Ferreira">Teresa Ferreira</name><affiliation wicri:level="4"><nlm:aff id="A1">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Segre, Ayellet V" sort="Segre, Ayellet V" uniqKey="Segre A" first="Ayellet V" last="Segrè">Ayellet V. Segrè</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A5">Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A6">Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Medicine, Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Steinthorsdottir, Valgerdur" sort="Steinthorsdottir, Valgerdur" uniqKey="Steinthorsdottir V" first="Valgerdur" last="Steinthorsdottir">Valgerdur Steinthorsdottir</name><affiliation wicri:level="1"><nlm:aff id="A7">deCODE Genetics, Reykjavik, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>deCODE Genetics, Reykjavik</wicri:regionArea><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation></author><author><name sortKey="Strawbridge, Rona J" sort="Strawbridge, Rona J" uniqKey="Strawbridge R" first="Rona J" last="Strawbridge">Rona J. Strawbridge</name><affiliation wicri:level="3"><nlm:aff id="A8">Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A9">Center for Molecular Medicine, Karolinska University Hospital Solna, Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Center for Molecular Medicine, Karolinska University Hospital Solna, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Khan, Hassan" sort="Khan, Hassan" uniqKey="Khan H" first="Hassan" last="Khan">Hassan Khan</name><affiliation wicri:level="4"><nlm:aff id="A10">Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Grallert, Harald" sort="Grallert, Harald" uniqKey="Grallert H" first="Harald" last="Grallert">Harald Grallert</name><affiliation wicri:level="1"><nlm:aff id="A11">Research Unit of Molecular Epidemiology, Helmholtz Zentrum Muenchen, Neuherberg, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Research Unit of Molecular Epidemiology, Helmholtz Zentrum Muenchen, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Mahajan, Anubha" sort="Mahajan, Anubha" uniqKey="Mahajan A" first="Anubha" last="Mahajan">Anubha Mahajan</name><affiliation wicri:level="4"><nlm:aff id="A1">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Prokopenko, Inga" sort="Prokopenko, Inga" uniqKey="Prokopenko I" first="Inga" last="Prokopenko">Inga Prokopenko</name><affiliation wicri:level="4"><nlm:aff id="A1">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A12">Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Kang, Hyun Min" sort="Kang, Hyun Min" uniqKey="Kang H" first="Hyun Min" last="Kang">Hyun Min Kang</name><affiliation wicri:level="2"><nlm:aff id="A4">Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Biostatistics, University of Michigan, Ann Arbor, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Dina, Christian" sort="Dina, Christian" uniqKey="Dina C" first="Christian" last="Dina">Christian Dina</name><affiliation wicri:level="3"><nlm:aff id="A13">Inserm UMR 1087, Nantes, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Inserm UMR 1087, Nantes</wicri:regionArea><placeName><region type="region">Pays de la Loire</region><region type="old region">Pays de la Loire</region><settlement type="city">Nantes</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A14">CNRS UMR 6291, Nantes, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>CNRS UMR 6291, Nantes</wicri:regionArea><placeName><region type="region">Pays de la Loire</region><region type="old region">Pays de la Loire</region><settlement type="city">Nantes</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A15">Nantes University, Nantes, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Nantes University, Nantes</wicri:regionArea><placeName><region type="region">Pays de la Loire</region><region type="old region">Pays de la Loire</region><settlement type="city">Nantes</settlement></placeName></affiliation></author><author><name sortKey="Esko, Tonu" sort="Esko, Tonu" uniqKey="Esko T" first="Tonu" last="Esko">Tonu Esko</name><affiliation wicri:level="1"><nlm:aff id="A16">Estonian Genome Center, University of Tartu, Tartu, Estonia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Estonie</country><wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A17">Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Estonie</country><wicri:regionArea>Institute of Molecular and Cell Biology, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation></author><author><name sortKey="Fraser, Ross M" sort="Fraser, Ross M" uniqKey="Fraser R" first="Ross M" last="Fraser">Ross M. Fraser</name><affiliation wicri:level="4"><nlm:aff id="A18">Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Kanoni, Stavroula" sort="Kanoni, Stavroula" uniqKey="Kanoni S" first="Stavroula" last="Kanoni">Stavroula Kanoni</name><affiliation wicri:level="1"><nlm:aff id="A19">Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Kumar, Ashish" sort="Kumar, Ashish" uniqKey="Kumar A" first="Ashish" last="Kumar">Ashish Kumar</name><affiliation wicri:level="4"><nlm:aff id="A1">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Lagou, Vasiliki" sort="Lagou, Vasiliki" uniqKey="Lagou V" first="Vasiliki" last="Lagou">Vasiliki Lagou</name><affiliation wicri:level="4"><nlm:aff id="A1">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Langenberg, Claudia" sort="Langenberg, Claudia" uniqKey="Langenberg C" first="Claudia" last="Langenberg">Claudia Langenberg</name><affiliation wicri:level="1"><nlm:aff id="A20">MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Luan, Jian An" sort="Luan, Jian An" uniqKey="Luan J" first="Jian'An" last="Luan">Jian'An Luan</name><affiliation wicri:level="1"><nlm:aff id="A20">MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Lindgren, Cecilia M" sort="Lindgren, Cecilia M" uniqKey="Lindgren C" first="Cecilia M" last="Lindgren">Cecilia M. Lindgren</name><affiliation wicri:level="4"><nlm:aff id="A1">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Muller Nurasyid, Martina" sort="Muller Nurasyid, Martina" uniqKey="Muller Nurasyid M" first="Martina" last="Müller-Nurasyid">Martina Müller-Nurasyid</name><affiliation wicri:level="3"><nlm:aff id="A21">Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A22">Institute of Genetic Epidemiology, Helmholtz Zentrum Muenchen, Neuherberg, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum Muenchen, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A23">Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-University, Munich, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-University, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName></affiliation></author><author><name sortKey="Pechlivanis, Sonali" sort="Pechlivanis, Sonali" uniqKey="Pechlivanis S" first="Sonali" last="Pechlivanis">Sonali Pechlivanis</name><affiliation wicri:level="1"><nlm:aff id="A24">Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, University Duisburg-Essen, Essen, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, University Duisburg-Essen, Essen</wicri:regionArea><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author><author><name sortKey="Rayner, N William" sort="Rayner, N William" uniqKey="Rayner N" first="N William" last="Rayner">N William Rayner</name><affiliation wicri:level="4"><nlm:aff id="A1">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A12">Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Scott, Laura J" sort="Scott, Laura J" uniqKey="Scott L" first="Laura J" last="Scott">Laura J. Scott</name><affiliation wicri:level="2"><nlm:aff id="A4">Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Biostatistics, University of Michigan, Ann Arbor, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Wiltshire, Steven" sort="Wiltshire, Steven" uniqKey="Wiltshire S" first="Steven" last="Wiltshire">Steven Wiltshire</name><affiliation wicri:level="4"><nlm:aff id="A1">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Yengo, Loic" sort="Yengo, Loic" uniqKey="Yengo L" first="Loic" last="Yengo">Loic Yengo</name><affiliation wicri:level="3"><nlm:aff id="A25">CNRS-UMR-8199, Institute of Biology and Lille 2 University, Pasteur Institute, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>CNRS-UMR-8199, Institute of Biology and Lille 2 University, Pasteur Institute, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A26">University Lille 1, Laboratory of Mathematics, CNRS-UMR 8524, MODAL team, INRIA Lille Nord-Europe, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>University Lille 1, Laboratory of Mathematics, CNRS-UMR 8524, MODAL team, INRIA Lille Nord-Europe, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation></author><author><name sortKey="Kinnunen, Leena" sort="Kinnunen, Leena" uniqKey="Kinnunen L" first="Leena" last="Kinnunen">Leena Kinnunen</name><affiliation wicri:level="1"><nlm:aff id="A27">Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Rossin, Elizabeth J" sort="Rossin, Elizabeth J" uniqKey="Rossin E" first="Elizabeth J" last="Rossin">Elizabeth J. Rossin</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A5">Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A28">Health Science and Technology MD Program, Harvard University and Massachusetts Institute of Technology, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Health Science and Technology MD Program, Harvard University and Massachusetts Institute of Technology, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A29">Harvard Biological and Biomedical Sciences Program, Harvard University, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Harvard Biological and Biomedical Sciences Program, Harvard University, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region><settlement type="city">Cambridge (Massachusetts)</settlement></placeName><orgName type="university">Université Harvard</orgName></affiliation></author><author><name sortKey="Raychaudhuri, Soumya" sort="Raychaudhuri, Soumya" uniqKey="Raychaudhuri S" first="Soumya" last="Raychaudhuri">Soumya Raychaudhuri</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A30">Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A31">Partners Center for Personalized Genomic Medicine, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Partners Center for Personalized Genomic Medicine, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Johnson, Andrew D" sort="Johnson, Andrew D" uniqKey="Johnson A" first="Andrew D" last="Johnson">Andrew D. Johnson</name><affiliation wicri:level="2"><nlm:aff id="A32">National Heart, Lung, and Blood Institute’s Framingham Heart Study, Framingham, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>National Heart, Lung, and Blood Institute’s Framingham Heart Study, Framingham, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Dimas, Antigone S" sort="Dimas, Antigone S" uniqKey="Dimas A" first="Antigone S" last="Dimas">Antigone S. Dimas</name><affiliation wicri:level="4"><nlm:aff id="A1">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation><affiliation wicri:level="1"><nlm:aff id="A33">Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suisse</country><wicri:regionArea>Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva</wicri:regionArea><wicri:noRegion>Geneva</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A34">Biomedical Sciences Research Center Al. Fleming, Vari, Greece.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Grèce</country><wicri:regionArea>Biomedical Sciences Research Center Al. Fleming, Vari</wicri:regionArea><wicri:noRegion>Vari</wicri:noRegion></affiliation></author><author><name sortKey="Loos, Ruth J F" sort="Loos, Ruth J F" uniqKey="Loos R" first="Ruth J F" last="Loos">Ruth J F. Loos</name><affiliation wicri:level="1"><nlm:aff id="A20">MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation><affiliation wicri:level="2"><nlm:aff id="A35">Charles R. Bronfman Institute for Personalized Medicine, Mount Sinai School of Medicine, New York, New York, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Charles R. Bronfman Institute for Personalized Medicine, Mount Sinai School of Medicine, New York, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A36">Child Health and Development Institute, Mount Sinai School of Medicine, New York, New York, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Child Health and Development Institute, Mount Sinai School of Medicine, New York, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A37">Department of Preventive Medicine, Mount Sinai School of Medicine, New York, New York, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Preventive Medicine, Mount Sinai School of Medicine, New York, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Vedantam, Sailaja" sort="Vedantam, Sailaja" uniqKey="Vedantam S" first="Sailaja" last="Vedantam">Sailaja Vedantam</name><affiliation wicri:level="2"><nlm:aff id="A38">Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A39">Division of Genetics and Endocrinology, Children's Hospital, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Division of Genetics and Endocrinology, Children's Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Chen, Han" sort="Chen, Han" uniqKey="Chen H" first="Han" last="Chen">Han Chen</name><affiliation wicri:level="2"><nlm:aff id="A40">Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Florez, Jose C" sort="Florez, Jose C" uniqKey="Florez J" first="Jose C" last="Florez">Jose C. Florez</name><affiliation wicri:level="2"><nlm:aff id="A5">Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A6">Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Medicine, Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A38">Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A41">Diabetes Research Center, Diabetes Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Diabetes Research Center, Diabetes Unit, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Fox, Caroline" sort="Fox, Caroline" uniqKey="Fox C" first="Caroline" last="Fox">Caroline Fox</name><affiliation wicri:level="2"><nlm:aff id="A32">National Heart, Lung, and Blood Institute’s Framingham Heart Study, Framingham, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>National Heart, Lung, and Blood Institute’s Framingham Heart Study, Framingham, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A42">Division of Endocrinology and Metabolism, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Division of Endocrinology and Metabolism, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Liu, Ching Ti" sort="Liu, Ching Ti" uniqKey="Liu C" first="Ching-Ti" last="Liu">Ching-Ti Liu</name><affiliation wicri:level="2"><nlm:aff id="A40">Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Rybin, Denis" sort="Rybin, Denis" uniqKey="Rybin D" first="Denis" last="Rybin">Denis Rybin</name><affiliation wicri:level="2"><nlm:aff id="A43">Boston University Data Coordinating Center, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Boston University Data Coordinating Center, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Couper, David J" sort="Couper, David J" uniqKey="Couper D" first="David J" last="Couper">David J. Couper</name><affiliation wicri:level="4"><nlm:aff id="A44">Collaborative Studies Coordinating Center, Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Collaborative Studies Coordinating Center, Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina</wicri:regionArea><placeName><region type="state">Caroline du Nord</region><settlement type="city">Chapel Hill (Caroline du Nord)</settlement></placeName><orgName type="university">Université de Caroline du Nord à Chapel Hill</orgName></affiliation></author><author><name sortKey="Kao, Wen Hong L" sort="Kao, Wen Hong L" uniqKey="Kao W" first="Wen Hong L" last="Kao">Wen Hong L. Kao</name><affiliation wicri:level="2"><nlm:aff id="A45">Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Li, Man" sort="Li, Man" uniqKey="Li M" first="Man" last="Li">Man Li</name><affiliation wicri:level="2"><nlm:aff id="A45">Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Cornelis, Marilyn C" sort="Cornelis, Marilyn C" uniqKey="Cornelis M" first="Marilyn C" last="Cornelis">Marilyn C. Cornelis</name><affiliation wicri:level="2"><nlm:aff id="A46">Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Kraft, Peter" sort="Kraft, Peter" uniqKey="Kraft P" first="Peter" last="Kraft">Peter Kraft</name><affiliation wicri:level="2"><nlm:aff id="A46">Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A47">Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Sun, Qi" sort="Sun, Qi" uniqKey="Sun Q" first="Qi" last="Sun">Qi Sun</name><affiliation wicri:level="2"><nlm:aff id="A46">Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A48">Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Van Dam, Rob M" sort="Van Dam, Rob M" uniqKey="Van Dam R" first="Rob M" last="Van Dam">Rob M. Van Dam</name><affiliation wicri:level="2"><nlm:aff id="A46">Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A49">Saw Swee Hock School of Public Health, National University of Singapore, Singapore.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Singapour</country><wicri:regionArea>Saw Swee Hock School of Public Health, National University of Singapore</wicri:regionArea><orgName type="university">Université nationale de Singapour</orgName></affiliation></author><author><name sortKey="Stringham, Heather M" sort="Stringham, Heather M" uniqKey="Stringham H" first="Heather M" last="Stringham">Heather M. Stringham</name><affiliation wicri:level="2"><nlm:aff id="A4">Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Biostatistics, University of Michigan, Ann Arbor, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Chines, Peter S" sort="Chines, Peter S" uniqKey="Chines P" first="Peter S" last="Chines">Peter S. Chines</name><affiliation wicri:level="2"><nlm:aff id="A50">National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Fischer, Krista" sort="Fischer, Krista" uniqKey="Fischer K" first="Krista" last="Fischer">Krista Fischer</name><affiliation wicri:level="1"><nlm:aff id="A16">Estonian Genome Center, University of Tartu, Tartu, Estonia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Estonie</country><wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation></author><author><name sortKey="Fontanillas, Pierre" sort="Fontanillas, Pierre" uniqKey="Fontanillas P" first="Pierre" last="Fontanillas">Pierre Fontanillas</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Holmen, Oddgeir L" sort="Holmen, Oddgeir L" uniqKey="Holmen O" first="Oddgeir L" last="Holmen">Oddgeir L. Holmen</name><affiliation wicri:level="1"><nlm:aff id="A51">HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Norvège</country><wicri:regionArea>HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger</wicri:regionArea><wicri:noRegion>Levanger</wicri:noRegion></affiliation></author><author><name sortKey="Hunt, Sarah E" sort="Hunt, Sarah E" uniqKey="Hunt S" first="Sarah E" last="Hunt">Sarah E. Hunt</name><affiliation wicri:level="1"><nlm:aff id="A19">Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Jackson, Anne U" sort="Jackson, Anne U" uniqKey="Jackson A" first="Anne U" last="Jackson">Anne U. Jackson</name><affiliation wicri:level="2"><nlm:aff id="A4">Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Biostatistics, University of Michigan, Ann Arbor, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Kong, Augustine" sort="Kong, Augustine" uniqKey="Kong A" first="Augustine" last="Kong">Augustine Kong</name><affiliation wicri:level="1"><nlm:aff id="A7">deCODE Genetics, Reykjavik, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>deCODE Genetics, Reykjavik</wicri:regionArea><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation></author><author><name sortKey="Lawrence, Robert" sort="Lawrence, Robert" uniqKey="Lawrence R" first="Robert" last="Lawrence">Robert Lawrence</name><affiliation wicri:level="1"><nlm:aff id="A52">Centre for Genetic Epidemiology and Biostatistics, The University of Western Australia, Nedlands, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>Centre for Genetic Epidemiology and Biostatistics, The University of Western Australia, Nedlands</wicri:regionArea><wicri:noRegion>Nedlands</wicri:noRegion></affiliation></author><author><name sortKey="Meyer, Julia" sort="Meyer, Julia" uniqKey="Meyer J" first="Julia" last="Meyer">Julia Meyer</name><affiliation wicri:level="1"><nlm:aff id="A22">Institute of Genetic Epidemiology, Helmholtz Zentrum Muenchen, Neuherberg, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum Muenchen, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Perry, John Rb" sort="Perry, John Rb" uniqKey="Perry J" first="John Rb" last="Perry">John Rb Perry</name><affiliation wicri:level="4"><nlm:aff id="A1">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation><affiliation wicri:level="1"><nlm:aff id="A53">Genetics of Complex Traits, Institute of Biomedical and Clinical Science, Peninsula Medical School, University of Exeter, Magdalen Road, Exeter, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Genetics of Complex Traits, Institute of Biomedical and Clinical Science, Peninsula Medical School, University of Exeter, Magdalen Road, Exeter</wicri:regionArea><wicri:noRegion>Exeter</wicri:noRegion></affiliation></author><author><name sortKey="Platou, Carl Gp" sort="Platou, Carl Gp" uniqKey="Platou C" first="Carl Gp" last="Platou">Carl Gp Platou</name><affiliation wicri:level="1"><nlm:aff id="A51">HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Norvège</country><wicri:regionArea>HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger</wicri:regionArea><wicri:noRegion>Levanger</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A54">Department of Internal Medicine, Levanger Hospital, Nord-Trøndelag Health Trust, Levanger, Norway.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Norvège</country><wicri:regionArea>Department of Internal Medicine, Levanger Hospital, Nord-Trøndelag Health Trust, Levanger</wicri:regionArea><wicri:noRegion>Levanger</wicri:noRegion></affiliation></author><author><name sortKey="Potter, Simon" sort="Potter, Simon" uniqKey="Potter S" first="Simon" last="Potter">Simon Potter</name><affiliation wicri:level="1"><nlm:aff id="A19">Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Rehnberg, Emil" sort="Rehnberg, Emil" uniqKey="Rehnberg E" first="Emil" last="Rehnberg">Emil Rehnberg</name><affiliation wicri:level="3"><nlm:aff id="A55">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Robertson, Neil" sort="Robertson, Neil" uniqKey="Robertson N" first="Neil" last="Robertson">Neil Robertson</name><affiliation wicri:level="4"><nlm:aff id="A1">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A12">Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Sivapalaratnam, Suthesh" sort="Sivapalaratnam, Suthesh" uniqKey="Sivapalaratnam S" first="Suthesh" last="Sivapalaratnam">Suthesh Sivapalaratnam</name><affiliation wicri:level="4"><nlm:aff id="A56">Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region><settlement type="city">Amsterdam</settlement></placeName><orgName type="university">Université d'Amsterdam</orgName></affiliation></author><author><name sortKey="Stan Kova, Alena" sort="Stan Kova, Alena" uniqKey="Stan Kova A" first="Alena" last="Stan Ková">Alena Stan Ková</name><affiliation wicri:level="1"><nlm:aff id="A57">Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation></author><author><name sortKey="Stirrups, Kathleen" sort="Stirrups, Kathleen" uniqKey="Stirrups K" first="Kathleen" last="Stirrups">Kathleen Stirrups</name><affiliation wicri:level="1"><nlm:aff id="A19">Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Thorleifsson, Gudmar" sort="Thorleifsson, Gudmar" uniqKey="Thorleifsson G" first="Gudmar" last="Thorleifsson">Gudmar Thorleifsson</name><affiliation wicri:level="1"><nlm:aff id="A7">deCODE Genetics, Reykjavik, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>deCODE Genetics, Reykjavik</wicri:regionArea><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation></author><author><name sortKey="Tikkanen, Emmi" sort="Tikkanen, Emmi" uniqKey="Tikkanen E" first="Emmi" last="Tikkanen">Emmi Tikkanen</name><affiliation wicri:level="1"><nlm:aff id="A58">Institute for Molecular Medicine Finland (FIMM), Helsinki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Institute for Molecular Medicine Finland (FIMM), Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A59">Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Wood, Andrew R" sort="Wood, Andrew R" uniqKey="Wood A" first="Andrew R" last="Wood">Andrew R. Wood</name><affiliation wicri:level="1"><nlm:aff id="A53">Genetics of Complex Traits, Institute of Biomedical and Clinical Science, Peninsula Medical School, University of Exeter, Magdalen Road, Exeter, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Genetics of Complex Traits, Institute of Biomedical and Clinical Science, Peninsula Medical School, University of Exeter, Magdalen Road, Exeter</wicri:regionArea><wicri:noRegion>Exeter</wicri:noRegion></affiliation></author><author><name sortKey="Almgren, Peter" sort="Almgren, Peter" uniqKey="Almgren P" first="Peter" last="Almgren">Peter Almgren</name><affiliation wicri:level="1"><nlm:aff id="A60">Lund University Diabetes Centre, Department of Clinical Science Malmö, Scania University Hospital, Lund University, Malmö, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Lund University Diabetes Centre, Department of Clinical Science Malmö, Scania University Hospital, Lund University, Malmö</wicri:regionArea><wicri:noRegion>Malmö</wicri:noRegion></affiliation></author><author><name sortKey="Atalay, Mustafa" sort="Atalay, Mustafa" uniqKey="Atalay M" first="Mustafa" last="Atalay">Mustafa Atalay</name><affiliation wicri:level="1"><nlm:aff id="A61">Institute of Biomedicine, Physiology, University of Eastern Finland, Kuopio Campus, Kuopio, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Institute of Biomedicine, Physiology, University of Eastern Finland, Kuopio Campus, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation></author><author><name sortKey="Benediktsson, Rafn" sort="Benediktsson, Rafn" uniqKey="Benediktsson R" first="Rafn" last="Benediktsson">Rafn Benediktsson</name><affiliation wicri:level="1"><nlm:aff id="A62">Faculty of Medicine, University of Iceland, Reykjavík, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>Faculty of Medicine, University of Iceland, Reykjavík</wicri:regionArea><wicri:noRegion>Reykjavík</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A63">Landspitali University Hospital, Reykjavík, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>Landspitali University Hospital, Reykjavík</wicri:regionArea><wicri:noRegion>Reykjavík</wicri:noRegion></affiliation></author><author><name sortKey="Bonnycastle, Lori L" sort="Bonnycastle, Lori L" uniqKey="Bonnycastle L" first="Lori L" last="Bonnycastle">Lori L. Bonnycastle</name><affiliation wicri:level="2"><nlm:aff id="A50">National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Burtt, Noel" sort="Burtt, Noel" uniqKey="Burtt N" first="Noël" last="Burtt">Noël Burtt</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Carey, Jason" sort="Carey, Jason" uniqKey="Carey J" first="Jason" last="Carey">Jason Carey</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Charpentier, Guillaume" sort="Charpentier, Guillaume" uniqKey="Charpentier G" first="Guillaume" last="Charpentier">Guillaume Charpentier</name><affiliation wicri:level="1"><nlm:aff id="A64">Endocrinology-Diabetology Unit, Corbeil-Essonnes Hospital, Corbeil-Essonnes, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Endocrinology-Diabetology Unit, Corbeil-Essonnes Hospital, Corbeil-Essonnes</wicri:regionArea><wicri:noRegion>Corbeil-Essonnes</wicri:noRegion><wicri:noRegion>Corbeil-Essonnes</wicri:noRegion></affiliation></author><author><name sortKey="Crenshaw, Andrew T" sort="Crenshaw, Andrew T" uniqKey="Crenshaw A" first="Andrew T" last="Crenshaw">Andrew T. Crenshaw</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Doney, Alex S F" sort="Doney, Alex S F" uniqKey="Doney A" first="Alex S F" last="Doney">Alex S F. Doney</name><affiliation wicri:level="1"><nlm:aff id="A65">Diabetes Research Centre, Biomedical Research Institute, University of Dundee, Ninewells Hospital, Dundee, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Diabetes Research Centre, Biomedical Research Institute, University of Dundee, Ninewells Hospital, Dundee</wicri:regionArea><wicri:noRegion>Dundee</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A66">Pharmacogenomics Centre, Biomedical Research Institute, University of Dundee, Ninewells Hospital, Dundee, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Pharmacogenomics Centre, Biomedical Research Institute, University of Dundee, Ninewells Hospital, Dundee</wicri:regionArea><wicri:noRegion>Dundee</wicri:noRegion></affiliation></author><author><name sortKey="Dorkhan, Mozhgan" sort="Dorkhan, Mozhgan" uniqKey="Dorkhan M" first="Mozhgan" last="Dorkhan">Mozhgan Dorkhan</name><affiliation wicri:level="1"><nlm:aff id="A60">Lund University Diabetes Centre, Department of Clinical Science Malmö, Scania University Hospital, Lund University, Malmö, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Lund University Diabetes Centre, Department of Clinical Science Malmö, Scania University Hospital, Lund University, Malmö</wicri:regionArea><wicri:noRegion>Malmö</wicri:noRegion></affiliation></author><author><name sortKey="Edkins, Sarah" sort="Edkins, Sarah" uniqKey="Edkins S" first="Sarah" last="Edkins">Sarah Edkins</name><affiliation wicri:level="1"><nlm:aff id="A19">Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Emilsson, Valur" sort="Emilsson, Valur" uniqKey="Emilsson V" first="Valur" last="Emilsson">Valur Emilsson</name><affiliation wicri:level="1"><nlm:aff id="A67">Icelandic Heart Association, Kopavogur, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea><wicri:noRegion>Kopavogur</wicri:noRegion></affiliation></author><author><name sortKey="Eury, Elodie" sort="Eury, Elodie" uniqKey="Eury E" first="Elodie" last="Eury">Elodie Eury</name><affiliation wicri:level="3"><nlm:aff id="A25">CNRS-UMR-8199, Institute of Biology and Lille 2 University, Pasteur Institute, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>CNRS-UMR-8199, Institute of Biology and Lille 2 University, Pasteur Institute, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation></author><author><name sortKey="Forsen, Tom" sort="Forsen, Tom" uniqKey="Forsen T" first="Tom" last="Forsen">Tom Forsen</name><affiliation wicri:level="4"><nlm:aff id="A68">Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Department of General Practice and Primary Health Care, University of Helsinki, Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A69">Vaasa Health Care Centre, Vaasa, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Vaasa Health Care Centre, Vaasa</wicri:regionArea><wicri:noRegion>Vaasa</wicri:noRegion></affiliation></author><author><name sortKey="Gertow, Karl" sort="Gertow, Karl" uniqKey="Gertow K" first="Karl" last="Gertow">Karl Gertow</name><affiliation wicri:level="3"><nlm:aff id="A8">Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A9">Center for Molecular Medicine, Karolinska University Hospital Solna, Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Center for Molecular Medicine, Karolinska University Hospital Solna, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Gigante, Bruna" sort="Gigante, Bruna" uniqKey="Gigante B" first="Bruna" last="Gigante">Bruna Gigante</name><affiliation wicri:level="3"><nlm:aff id="A70">Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Grant, George B" sort="Grant, George B" uniqKey="Grant G" first="George B" last="Grant">George B. Grant</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Groves, Christopher J" sort="Groves, Christopher J" uniqKey="Groves C" first="Christopher J" last="Groves">Christopher J. Groves</name><affiliation wicri:level="4"><nlm:aff id="A12">Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Guiducci, Candace" sort="Guiducci, Candace" uniqKey="Guiducci C" first="Candace" last="Guiducci">Candace Guiducci</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Herder, Christian" sort="Herder, Christian" uniqKey="Herder C" first="Christian" last="Herder">Christian Herder</name><affiliation wicri:level="3"><nlm:aff id="A71">Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Düsseldorf</region><settlement type="city">Düsseldorf</settlement></placeName></affiliation></author><author><name sortKey="Hreidarsson, Astradur B" sort="Hreidarsson, Astradur B" uniqKey="Hreidarsson A" first="Astradur B" last="Hreidarsson">Astradur B. Hreidarsson</name><affiliation wicri:level="1"><nlm:aff id="A63">Landspitali University Hospital, Reykjavík, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>Landspitali University Hospital, Reykjavík</wicri:regionArea><wicri:noRegion>Reykjavík</wicri:noRegion></affiliation></author><author><name sortKey="Hui, Jennie" sort="Hui, Jennie" uniqKey="Hui J" first="Jennie" last="Hui">Jennie Hui</name><affiliation wicri:level="1"><nlm:aff id="A72">Busselton Population Medical Research Institute, Sir Charles Gairdner Hospital, Nedlands, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>Busselton Population Medical Research Institute, Sir Charles Gairdner Hospital, Nedlands</wicri:regionArea><wicri:noRegion>Nedlands</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A73">PathWest Laboratory Medicine of Western Australia, QEII Medical Centre, Nedlands, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>PathWest Laboratory Medicine of Western Australia, QEII Medical Centre, Nedlands</wicri:regionArea><wicri:noRegion>Nedlands</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A74">School of Pathology and Laboratory Medicine, The University of Western Australia, Nedlands, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>School of Pathology and Laboratory Medicine, The University of Western Australia, Nedlands</wicri:regionArea><wicri:noRegion>Nedlands</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A75">School of Population Health, The University of Western Australia, Nedlands, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>School of Population Health, The University of Western Australia, Nedlands</wicri:regionArea><wicri:noRegion>Nedlands</wicri:noRegion></affiliation></author><author><name sortKey="James, Alan" sort="James, Alan" uniqKey="James A" first="Alan" last="James">Alan James</name><affiliation wicri:level="1"><nlm:aff id="A72">Busselton Population Medical Research Institute, Sir Charles Gairdner Hospital, Nedlands, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>Busselton Population Medical Research Institute, Sir Charles Gairdner Hospital, Nedlands</wicri:regionArea><wicri:noRegion>Nedlands</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A76">Department of Pulmonary Physiology and Sleep Medicine, West Australian Sleep Disorders Research Institute, Queen Elizabeth II Medical Centre, Hospital Avenue, Nedlands, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>Department of Pulmonary Physiology and Sleep Medicine, West Australian Sleep Disorders Research Institute, Queen Elizabeth II Medical Centre, Hospital Avenue, Nedlands</wicri:regionArea><wicri:noRegion>Nedlands</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A77">School of Medicine and Pharmacology, University of Western Australia, Nedlands, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>School of Medicine and Pharmacology, University of Western Australia, Nedlands</wicri:regionArea><wicri:noRegion>Nedlands</wicri:noRegion></affiliation></author><author><name sortKey="Jonsson, Anna" sort="Jonsson, Anna" uniqKey="Jonsson A" first="Anna" last="Jonsson">Anna Jonsson</name><affiliation wicri:level="1"><nlm:aff id="A60">Lund University Diabetes Centre, Department of Clinical Science Malmö, Scania University Hospital, Lund University, Malmö, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Lund University Diabetes Centre, Department of Clinical Science Malmö, Scania University Hospital, Lund University, Malmö</wicri:regionArea><wicri:noRegion>Malmö</wicri:noRegion></affiliation></author><author><name sortKey="Rathmann, Wolfgang" sort="Rathmann, Wolfgang" uniqKey="Rathmann W" first="Wolfgang" last="Rathmann">Wolfgang Rathmann</name><affiliation wicri:level="3"><nlm:aff id="A78">Institute of Biometrics and Epidemiology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Institute of Biometrics and Epidemiology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Düsseldorf</region><settlement type="city">Düsseldorf</settlement></placeName></affiliation></author><author><name sortKey="Klopp, Norman" sort="Klopp, Norman" uniqKey="Klopp N" first="Norman" last="Klopp">Norman Klopp</name><affiliation wicri:level="1"><nlm:aff id="A11">Research Unit of Molecular Epidemiology, Helmholtz Zentrum Muenchen, Neuherberg, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Research Unit of Molecular Epidemiology, Helmholtz Zentrum Muenchen, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Kravic, Jasmina" sort="Kravic, Jasmina" uniqKey="Kravic J" first="Jasmina" last="Kravic">Jasmina Kravic</name><affiliation wicri:level="1"><nlm:aff id="A60">Lund University Diabetes Centre, Department of Clinical Science Malmö, Scania University Hospital, Lund University, Malmö, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Lund University Diabetes Centre, Department of Clinical Science Malmö, Scania University Hospital, Lund University, Malmö</wicri:regionArea><wicri:noRegion>Malmö</wicri:noRegion></affiliation></author><author><name sortKey="Krjutskov, Kaarel" sort="Krjutskov, Kaarel" uniqKey="Krjutskov K" first="Kaarel" last="Krjutškov">Kaarel Krjutškov</name><affiliation wicri:level="1"><nlm:aff id="A16">Estonian Genome Center, University of Tartu, Tartu, Estonia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Estonie</country><wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation></author><author><name sortKey="Langford, Cordelia" sort="Langford, Cordelia" uniqKey="Langford C" first="Cordelia" last="Langford">Cordelia Langford</name><affiliation wicri:level="1"><nlm:aff id="A19">Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Leander, Karin" sort="Leander, Karin" uniqKey="Leander K" first="Karin" last="Leander">Karin Leander</name><affiliation wicri:level="3"><nlm:aff id="A70">Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Lindholm, Eero" sort="Lindholm, Eero" uniqKey="Lindholm E" first="Eero" last="Lindholm">Eero Lindholm</name><affiliation wicri:level="1"><nlm:aff id="A60">Lund University Diabetes Centre, Department of Clinical Science Malmö, Scania University Hospital, Lund University, Malmö, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Lund University Diabetes Centre, Department of Clinical Science Malmö, Scania University Hospital, Lund University, Malmö</wicri:regionArea><wicri:noRegion>Malmö</wicri:noRegion></affiliation></author><author><name sortKey="Lobbens, Stephane" sort="Lobbens, Stephane" uniqKey="Lobbens S" first="Stéphane" last="Lobbens">Stéphane Lobbens</name><affiliation wicri:level="3"><nlm:aff id="A25">CNRS-UMR-8199, Institute of Biology and Lille 2 University, Pasteur Institute, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>CNRS-UMR-8199, Institute of Biology and Lille 2 University, Pasteur Institute, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation></author><author><name sortKey="M Nnisto, Satu" sort="M Nnisto, Satu" uniqKey="M Nnisto S" first="Satu" last="M Nnistö">Satu M Nnistö</name><affiliation wicri:level="1"><nlm:aff id="A59">Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Mirza, Ghazala" sort="Mirza, Ghazala" uniqKey="Mirza G" first="Ghazala" last="Mirza">Ghazala Mirza</name><affiliation wicri:level="4"><nlm:aff id="A1">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Muhleisen, Thomas W" sort="Muhleisen, Thomas W" uniqKey="Muhleisen T" first="Thomas W" last="Mühleisen">Thomas W. Mühleisen</name><affiliation wicri:level="3"><nlm:aff id="A79">Institute of Human Genetics, University of Bonn, Bonn, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Institute of Human Genetics, University of Bonn, Bonn</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Cologne</region><settlement type="city">Bonn</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A80">Department of Genomics, Life & Brain Center, University of Bonn, Bonn, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Department of Genomics, Life & Brain Center, University of Bonn, Bonn</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Cologne</region><settlement type="city">Bonn</settlement></placeName></affiliation></author><author><name sortKey="Musk, Bill" sort="Musk, Bill" uniqKey="Musk B" first="Bill" last="Musk">Bill Musk</name><affiliation wicri:level="1"><nlm:aff id="A72">Busselton Population Medical Research Institute, Sir Charles Gairdner Hospital, Nedlands, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>Busselton Population Medical Research Institute, Sir Charles Gairdner Hospital, Nedlands</wicri:regionArea><wicri:noRegion>Nedlands</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A75">School of Population Health, The University of Western Australia, Nedlands, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>School of Population Health, The University of Western Australia, Nedlands</wicri:regionArea><wicri:noRegion>Nedlands</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A77">School of Medicine and Pharmacology, University of Western Australia, Nedlands, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>School of Medicine and Pharmacology, University of Western Australia, Nedlands</wicri:regionArea><wicri:noRegion>Nedlands</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A81">Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands</wicri:regionArea><wicri:noRegion>Nedlands</wicri:noRegion></affiliation></author><author><name sortKey="Parkin, Melissa" sort="Parkin, Melissa" uniqKey="Parkin M" first="Melissa" last="Parkin">Melissa Parkin</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Rallidis, Loukianos" sort="Rallidis, Loukianos" uniqKey="Rallidis L" first="Loukianos" last="Rallidis">Loukianos Rallidis</name><affiliation wicri:level="3"><nlm:aff id="A82">University General Hospital Attikon, Athens, Greece.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Grèce</country><wicri:regionArea>University General Hospital Attikon, Athens</wicri:regionArea><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region></placeName></affiliation></author><author><name sortKey="Saramies, Jouko" sort="Saramies, Jouko" uniqKey="Saramies J" first="Jouko" last="Saramies">Jouko Saramies</name><affiliation wicri:level="1"><nlm:aff id="A83">South Karelia Central Hospital, Lappeenranta, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>South Karelia Central Hospital, Lappeenranta</wicri:regionArea><wicri:noRegion>Lappeenranta</wicri:noRegion></affiliation></author><author><name sortKey="Sennblad, Bengt" sort="Sennblad, Bengt" uniqKey="Sennblad B" first="Bengt" last="Sennblad">Bengt Sennblad</name><affiliation wicri:level="3"><nlm:aff id="A8">Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A9">Center for Molecular Medicine, Karolinska University Hospital Solna, Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Center for Molecular Medicine, Karolinska University Hospital Solna, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Shah, Sonia" sort="Shah, Sonia" uniqKey="Shah S" first="Sonia" last="Shah">Sonia Shah</name><affiliation wicri:level="4"><nlm:aff id="A84">UCL Genetics Institute, Department of Genetics, Evolution and Environment, University College London, London, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>UCL Genetics Institute, Department of Genetics, Evolution and Environment, University College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">University College de Londres</orgName></affiliation></author><author><name sortKey="Sigur Sson, Gunnar" sort="Sigur Sson, Gunnar" uniqKey="Sigur Sson G" first="Gunnar" last="Sigur Sson">Gunnar Sigur Sson</name><affiliation wicri:level="1"><nlm:aff id="A63">Landspitali University Hospital, Reykjavík, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>Landspitali University Hospital, Reykjavík</wicri:regionArea><wicri:noRegion>Reykjavík</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A67">Icelandic Heart Association, Kopavogur, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea><wicri:noRegion>Kopavogur</wicri:noRegion></affiliation></author><author><name sortKey="Silveira, Angela" sort="Silveira, Angela" uniqKey="Silveira A" first="Angela" last="Silveira">Angela Silveira</name><affiliation wicri:level="3"><nlm:aff id="A8">Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A9">Center for Molecular Medicine, Karolinska University Hospital Solna, Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Center for Molecular Medicine, Karolinska University Hospital Solna, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Steinbach, Gerald" sort="Steinbach, Gerald" uniqKey="Steinbach G" first="Gerald" last="Steinbach">Gerald Steinbach</name><affiliation wicri:level="4"><nlm:aff id="A85">Department of Clinical Chemistry and Central Laboratory, University of Ulm, Ulm, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Department of Clinical Chemistry and Central Laboratory, University of Ulm, Ulm</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Ulm</settlement><settlement type="city">Ulm</settlement></placeName><orgName type="university">Université d'Ulm</orgName></affiliation></author><author><name sortKey="Thorand, Barbara" sort="Thorand, Barbara" uniqKey="Thorand B" first="Barbara" last="Thorand">Barbara Thorand</name><affiliation wicri:level="1"><nlm:aff id="A86">Institute of Epidemiology II, Helmholtz Zentrum Muenchen, Neuherberg, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Institute of Epidemiology II, Helmholtz Zentrum Muenchen, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Trakalo, Joseph" sort="Trakalo, Joseph" uniqKey="Trakalo J" first="Joseph" last="Trakalo">Joseph Trakalo</name><affiliation wicri:level="4"><nlm:aff id="A1">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Veglia, Fabrizio" sort="Veglia, Fabrizio" uniqKey="Veglia F" first="Fabrizio" last="Veglia">Fabrizio Veglia</name><affiliation wicri:level="3"><nlm:aff id="A87">Centro Cardiologico Monzino, IRCCS, Milan, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Centro Cardiologico Monzino, IRCCS, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Wennauer, Roman" sort="Wennauer, Roman" uniqKey="Wennauer R" first="Roman" last="Wennauer">Roman Wennauer</name><affiliation wicri:level="4"><nlm:aff id="A85">Department of Clinical Chemistry and Central Laboratory, University of Ulm, Ulm, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Department of Clinical Chemistry and Central Laboratory, University of Ulm, Ulm</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Ulm</settlement><settlement type="city">Ulm</settlement></placeName><orgName type="university">Université d'Ulm</orgName></affiliation></author><author><name sortKey="Winckler, Wendy" sort="Winckler, Wendy" uniqKey="Winckler W" first="Wendy" last="Winckler">Wendy Winckler</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Zabaneh, Delilah" sort="Zabaneh, Delilah" uniqKey="Zabaneh D" first="Delilah" last="Zabaneh">Delilah Zabaneh</name><affiliation wicri:level="4"><nlm:aff id="A84">UCL Genetics Institute, Department of Genetics, Evolution and Environment, University College London, London, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>UCL Genetics Institute, Department of Genetics, Evolution and Environment, University College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">University College de Londres</orgName></affiliation></author><author><name sortKey="Campbell, Harry" sort="Campbell, Harry" uniqKey="Campbell H" first="Harry" last="Campbell">Harry Campbell</name><affiliation wicri:level="4"><nlm:aff id="A18">Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A88">MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Western General Hospital, Edinburgh, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Western General Hospital, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Van Duijn, Cornelia" sort="Van Duijn, Cornelia" uniqKey="Van Duijn C" first="Cornelia" last="Van Duijn">Cornelia Van Duijn</name><affiliation wicri:level="3"><nlm:aff id="A89">Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A90">Netherland Genomics Initiative, Netherlands Consortium for Healthy Ageing and Centre for Medical Systems Biology, Rotterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Netherland Genomics Initiative, Netherlands Consortium for Healthy Ageing and Centre for Medical Systems Biology, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Uitterlinden89, Andre G" sort="Uitterlinden89, Andre G" uniqKey="Uitterlinden89 A" first="Andre G" last="Uitterlinden89-">Andre G. Uitterlinden89-</name><affiliation wicri:level="3"><nlm:aff id="A89">Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A90">Netherland Genomics Initiative, Netherlands Consortium for Healthy Ageing and Centre for Medical Systems Biology, Rotterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Netherland Genomics Initiative, Netherlands Consortium for Healthy Ageing and Centre for Medical Systems Biology, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A91">Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name><affiliation wicri:level="3"><nlm:aff id="A89">Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Sijbrands, Eric" sort="Sijbrands, Eric" uniqKey="Sijbrands E" first="Eric" last="Sijbrands">Eric Sijbrands</name><affiliation wicri:level="3"><nlm:aff id="A91">Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Abecasis, Goncalo R" sort="Abecasis, Goncalo R" uniqKey="Abecasis G" first="Goncalo R" last="Abecasis">Goncalo R. Abecasis</name><affiliation wicri:level="2"><nlm:aff id="A4">Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Biostatistics, University of Michigan, Ann Arbor, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Owen, Katharine R" sort="Owen, Katharine R" uniqKey="Owen K" first="Katharine R" last="Owen">Katharine R. Owen</name><affiliation wicri:level="4"><nlm:aff id="A12">Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A92">Oxford National Institute for Health Research Biomedical Research Centre, Churchill Hospital, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Oxford National Institute for Health Research Biomedical Research Centre, Churchill Hospital, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="Zeggini, Eleftheria" sort="Zeggini, Eleftheria" uniqKey="Zeggini E" first="Eleftheria" last="Zeggini">Eleftheria Zeggini</name><affiliation wicri:level="1"><nlm:aff id="A19">Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Trip, Mieke D" sort="Trip, Mieke D" uniqKey="Trip M" first="Mieke D" last="Trip">Mieke D. Trip</name><affiliation wicri:level="4"><nlm:aff id="A56">Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region><settlement type="city">Amsterdam</settlement></placeName><orgName type="university">Université d'Amsterdam</orgName></affiliation></author><author><name sortKey="Forouhi, Nita G" sort="Forouhi, Nita G" uniqKey="Forouhi N" first="Nita G" last="Forouhi">Nita G. Forouhi</name><affiliation wicri:level="1"><nlm:aff id="A20">MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Syv Nen, Ann Christine" sort="Syv Nen, Ann Christine" uniqKey="Syv Nen A" first="Ann-Christine" last="Syv Nen">Ann-Christine Syv Nen</name><affiliation wicri:level="4"><nlm:aff id="A93">Molecular Medicine, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Molecular Medicine, Department of Medical Sciences, Uppsala University, Uppsala</wicri:regionArea><orgName type="university">Université d'Uppsala</orgName><placeName><settlement type="city">Uppsala</settlement><region nuts="1">Svealand</region><region nuts="1">East Middle Sweden</region></placeName></affiliation></author><author><name sortKey="Eriksson, Johan G" sort="Eriksson, Johan G" uniqKey="Eriksson J" first="Johan G" last="Eriksson">Johan G. Eriksson</name><affiliation wicri:level="1"><nlm:aff id="A59">Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:aff id="A68">Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Department of General Practice and Primary Health Care, University of Helsinki, Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A94">Unit of General Practice, Helsinki University General Hospital, Helsinki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Unit of General Practice, Helsinki University General Hospital, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A95">Folkhälsan Research Center, Helsinki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Folkhälsan Research Center, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Peltonen, Leena" sort="Peltonen, Leena" uniqKey="Peltonen L" first="Leena" last="Peltonen">Leena Peltonen</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A19">Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A58">Institute for Molecular Medicine Finland (FIMM), Helsinki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Institute for Molecular Medicine Finland (FIMM), Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A59">Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Nothen, Markus M" sort="Nothen, Markus M" uniqKey="Nothen M" first="Markus M" last="Nöthen">Markus M. Nöthen</name><affiliation wicri:level="3"><nlm:aff id="A79">Institute of Human Genetics, University of Bonn, Bonn, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Institute of Human Genetics, University of Bonn, Bonn</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Cologne</region><settlement type="city">Bonn</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A80">Department of Genomics, Life & Brain Center, University of Bonn, Bonn, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Department of Genomics, Life & Brain Center, University of Bonn, Bonn</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Cologne</region><settlement type="city">Bonn</settlement></placeName></affiliation></author><author><name sortKey="Balkau, Beverley" sort="Balkau, Beverley" uniqKey="Balkau B" first="Beverley" last="Balkau">Beverley Balkau</name><affiliation wicri:level="1"><nlm:aff id="A96">INSERM CESP U1018, Villejuif, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>INSERM CESP U1018, Villejuif</wicri:regionArea><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A97">University Paris Sud 11, UMRS 1018, Villejuif, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>University Paris Sud 11, UMRS 1018, Villejuif</wicri:regionArea><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation></author><author><name sortKey="Palmer, Colin N A" sort="Palmer, Colin N A" uniqKey="Palmer C" first="Colin N A" last="Palmer">Colin N A. Palmer</name><affiliation wicri:level="1"><nlm:aff id="A65">Diabetes Research Centre, Biomedical Research Institute, University of Dundee, Ninewells Hospital, Dundee, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Diabetes Research Centre, Biomedical Research Institute, University of Dundee, Ninewells Hospital, Dundee</wicri:regionArea><wicri:noRegion>Dundee</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A66">Pharmacogenomics Centre, Biomedical Research Institute, University of Dundee, Ninewells Hospital, Dundee, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Pharmacogenomics Centre, Biomedical Research Institute, University of Dundee, Ninewells Hospital, Dundee</wicri:regionArea><wicri:noRegion>Dundee</wicri:noRegion></affiliation></author><author><name sortKey="Lyssenko, Valeriya" sort="Lyssenko, Valeriya" uniqKey="Lyssenko V" first="Valeriya" last="Lyssenko">Valeriya Lyssenko</name><affiliation wicri:level="1"><nlm:aff id="A60">Lund University Diabetes Centre, Department of Clinical Science Malmö, Scania University Hospital, Lund University, Malmö, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Lund University Diabetes Centre, Department of Clinical Science Malmö, Scania University Hospital, Lund University, Malmö</wicri:regionArea><wicri:noRegion>Malmö</wicri:noRegion></affiliation></author><author><name sortKey="Tuomi, Tiinamaija" sort="Tuomi, Tiinamaija" uniqKey="Tuomi T" first="Tiinamaija" last="Tuomi">Tiinamaija Tuomi</name><affiliation wicri:level="1"><nlm:aff id="A95">Folkhälsan Research Center, Helsinki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Folkhälsan Research Center, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A98">Department of Medicine, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Department of Medicine, Helsinki University Hospital, University of Helsinki, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Isomaa, Bo" sort="Isomaa, Bo" uniqKey="Isomaa B" first="Bo" last="Isomaa">Bo Isomaa</name><affiliation wicri:level="1"><nlm:aff id="A95">Folkhälsan Research Center, Helsinki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Folkhälsan Research Center, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A99">Department of Social Services and Health Care, Jakobstad, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Department of Social Services and Health Care, Jakobstad</wicri:regionArea><wicri:noRegion>Jakobstad</wicri:noRegion></affiliation></author><author><name sortKey="Hunter, David J" sort="Hunter, David J" uniqKey="Hunter D" first="David J" last="Hunter">David J. Hunter</name><affiliation wicri:level="2"><nlm:aff id="A46">Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A47">Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A48">Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Qi, Lu" sort="Qi, Lu" uniqKey="Qi L" first="Lu" last="Qi">Lu Qi</name><affiliation wicri:level="2"><nlm:aff id="A46">Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A48">Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Shuldiner, Alan R" sort="Shuldiner, Alan R" uniqKey="Shuldiner A" first="Alan R" last="Shuldiner">Alan R. Shuldiner</name><affiliation wicri:level="2"><nlm:aff id="A100">Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A101">Geriatric Research Education and Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, Maryland, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Geriatric Research Education and Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A102">Program in Personalised and Genomic Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Program in Personalised and Genomic Medicine, University of Maryland School of Medicine, Baltimore, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Roden, Michael" sort="Roden, Michael" uniqKey="Roden M" first="Michael" last="Roden">Michael Roden</name><affiliation wicri:level="3"><nlm:aff id="A71">Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Düsseldorf</region><settlement type="city">Düsseldorf</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A103">Department of Medicine/Metabolic Diseases, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Department of Medicine/Metabolic Diseases, Heinrich Heine University Düsseldorf, Düsseldorf</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Düsseldorf</region><settlement type="city">Düsseldorf</settlement></placeName></affiliation></author><author><name sortKey="Barroso, Ines" sort="Barroso, Ines" uniqKey="Barroso I" first="Ines" last="Barroso">Ines Barroso</name><affiliation wicri:level="1"><nlm:aff id="A19">Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A104">University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A105">NIHR Cambridge Biomedical Research Centre, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>NIHR Cambridge Biomedical Research Centre, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Wilsgaard, Tom" sort="Wilsgaard, Tom" uniqKey="Wilsgaard T" first="Tom" last="Wilsgaard">Tom Wilsgaard</name><affiliation wicri:level="1"><nlm:aff id="A106">Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Norvège</country><wicri:regionArea>Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø</wicri:regionArea><wicri:noRegion>Tromsø</wicri:noRegion></affiliation></author><author><name sortKey="Beilby, John" sort="Beilby, John" uniqKey="Beilby J" first="John" last="Beilby">John Beilby</name><affiliation wicri:level="1"><nlm:aff id="A72">Busselton Population Medical Research Institute, Sir Charles Gairdner Hospital, Nedlands, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>Busselton Population Medical Research Institute, Sir Charles Gairdner Hospital, Nedlands</wicri:regionArea><wicri:noRegion>Nedlands</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A73">PathWest Laboratory Medicine of Western Australia, QEII Medical Centre, Nedlands, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>PathWest Laboratory Medicine of Western Australia, QEII Medical Centre, Nedlands</wicri:regionArea><wicri:noRegion>Nedlands</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A74">School of Pathology and Laboratory Medicine, The University of Western Australia, Nedlands, Australia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Australie</country><wicri:regionArea>School of Pathology and Laboratory Medicine, The University of Western Australia, Nedlands</wicri:regionArea><wicri:noRegion>Nedlands</wicri:noRegion></affiliation></author><author><name sortKey="Hovingh, Kees" sort="Hovingh, Kees" uniqKey="Hovingh K" first="Kees" last="Hovingh">Kees Hovingh</name><affiliation wicri:level="4"><nlm:aff id="A56">Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region><settlement type="city">Amsterdam</settlement></placeName><orgName type="university">Université d'Amsterdam</orgName></affiliation></author><author><name sortKey="Price, Jackie F" sort="Price, Jackie F" uniqKey="Price J" first="Jackie F" last="Price">Jackie F. Price</name><affiliation wicri:level="4"><nlm:aff id="A18">Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Wilson, James F" sort="Wilson, James F" uniqKey="Wilson J" first="James F" last="Wilson">James F. Wilson</name><affiliation wicri:level="4"><nlm:aff id="A18">Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A88">MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Western General Hospital, Edinburgh, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Western General Hospital, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Rauramaa, Rainer" sort="Rauramaa, Rainer" uniqKey="Rauramaa R" first="Rainer" last="Rauramaa">Rainer Rauramaa</name><affiliation wicri:level="1"><nlm:aff id="A107">Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Kuopio Research Institute of Exercise Medicine, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A108">Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation></author><author><name sortKey="Lakka, Timo A" sort="Lakka, Timo A" uniqKey="Lakka T" first="Timo A" last="Lakka">Timo A. Lakka</name><affiliation wicri:level="1"><nlm:aff id="A61">Institute of Biomedicine, Physiology, University of Eastern Finland, Kuopio Campus, Kuopio, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Institute of Biomedicine, Physiology, University of Eastern Finland, Kuopio Campus, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A107">Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Kuopio Research Institute of Exercise Medicine, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation></author><author><name sortKey="Lind, Lars" sort="Lind, Lars" uniqKey="Lind L" first="Lars" last="Lind">Lars Lind</name><affiliation wicri:level="4"><nlm:aff id="A109">Department of Medical Sciences, Uppsala University, Akademiska Sjukhuset, Uppsala, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Department of Medical Sciences, Uppsala University, Akademiska Sjukhuset, Uppsala</wicri:regionArea><orgName type="university">Université d'Uppsala</orgName><placeName><settlement type="city">Uppsala</settlement><region nuts="1">Svealand</region><region nuts="1">East Middle Sweden</region></placeName></affiliation></author><author><name sortKey="Dedoussis, George" sort="Dedoussis, George" uniqKey="Dedoussis G" first="George" last="Dedoussis">George Dedoussis</name><affiliation wicri:level="4"><nlm:aff id="A110">Department of Dietetics-Nutrition, Harokopio University, Athens, Greece.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Grèce</country><wicri:regionArea>Department of Dietetics-Nutrition, Harokopio University, Athens</wicri:regionArea><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region><settlement type="city">Athènes</settlement></placeName><orgName type="university">Université Harokopio</orgName></affiliation></author><author><name sortKey="Nj Lstad, Inger" sort="Nj Lstad, Inger" uniqKey="Nj Lstad I" first="Inger" last="Nj Lstad">Inger Nj Lstad</name><affiliation wicri:level="1"><nlm:aff id="A106">Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Norvège</country><wicri:regionArea>Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø</wicri:regionArea><wicri:noRegion>Tromsø</wicri:noRegion></affiliation></author><author><name sortKey="Pedersen, Nancy L" sort="Pedersen, Nancy L" uniqKey="Pedersen N" first="Nancy L" last="Pedersen">Nancy L. Pedersen</name><affiliation wicri:level="3"><nlm:aff id="A55">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Khaw, Kay Tee" sort="Khaw, Kay Tee" uniqKey="Khaw K" first="Kay-Tee" last="Khaw">Kay-Tee Khaw</name><affiliation wicri:level="4"><nlm:aff id="A10">Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Wareham, Nicholas J" sort="Wareham, Nicholas J" uniqKey="Wareham N" first="Nicholas J" last="Wareham">Nicholas J. Wareham</name><affiliation wicri:level="1"><nlm:aff id="A20">MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Keinanen Kiukaanniemi, Sirkka M" sort="Keinanen Kiukaanniemi, Sirkka M" uniqKey="Keinanen Kiukaanniemi S" first="Sirkka M" last="Keinanen-Kiukaanniemi">Sirkka M. Keinanen-Kiukaanniemi</name><affiliation wicri:level="1"><nlm:aff id="A111">Faculty of Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Faculty of Medicine, Institute of Health Sciences, University of Oulu, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A112">Unit of General Practice, Oulu University Hospital, Oulu, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Unit of General Practice, Oulu University Hospital, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation></author><author><name sortKey="Saaristo, Timo E" sort="Saaristo, Timo E" uniqKey="Saaristo T" first="Timo E" last="Saaristo">Timo E. Saaristo</name><affiliation wicri:level="1"><nlm:aff id="A113">Finnish Diabetes Association, Tampere, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Finnish Diabetes Association, Tampere</wicri:regionArea><wicri:noRegion>Tampere</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A114">Pirkanmaa Hospital District, Tampere, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Pirkanmaa Hospital District, Tampere</wicri:regionArea><wicri:noRegion>Tampere</wicri:noRegion></affiliation></author><author><name sortKey="Korpi Hyov Lti, Eeva" sort="Korpi Hyov Lti, Eeva" uniqKey="Korpi Hyov Lti E" first="Eeva" last="Korpi-Hyöv Lti">Eeva Korpi-Hyöv Lti</name><affiliation wicri:level="1"><nlm:aff id="A115">South Ostrobothnia Central Hospital, Seinäjoki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>South Ostrobothnia Central Hospital, Seinäjoki</wicri:regionArea><wicri:noRegion>Seinäjoki</wicri:noRegion></affiliation></author><author><name sortKey="Saltevo, Juha" sort="Saltevo, Juha" uniqKey="Saltevo J" first="Juha" last="Saltevo">Juha Saltevo</name><affiliation wicri:level="1"><nlm:aff id="A116">Department of Medicine, Central Finland Central Hospital, Jyväskylä, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Department of Medicine, Central Finland Central Hospital, Jyväskylä</wicri:regionArea><wicri:noRegion>Jyväskylä</wicri:noRegion></affiliation></author><author><name sortKey="Laakso, Markku" sort="Laakso, Markku" uniqKey="Laakso M" first="Markku" last="Laakso">Markku Laakso</name><affiliation wicri:level="1"><nlm:aff id="A57">Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation></author><author><name sortKey="Kuusisto, Johanna" sort="Kuusisto, Johanna" uniqKey="Kuusisto J" first="Johanna" last="Kuusisto">Johanna Kuusisto</name><affiliation wicri:level="1"><nlm:aff id="A57">Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation></author><author><name sortKey="Metspalu, Andres" sort="Metspalu, Andres" uniqKey="Metspalu A" first="Andres" last="Metspalu">Andres Metspalu</name><affiliation wicri:level="1"><nlm:aff id="A16">Estonian Genome Center, University of Tartu, Tartu, Estonia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Estonie</country><wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A17">Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Estonie</country><wicri:regionArea>Institute of Molecular and Cell Biology, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation></author><author><name sortKey="Collins, Francis S" sort="Collins, Francis S" uniqKey="Collins F" first="Francis S" last="Collins">Francis S. Collins</name><affiliation wicri:level="2"><nlm:aff id="A50">National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Mohlke, Karen L" sort="Mohlke, Karen L" uniqKey="Mohlke K" first="Karen L" last="Mohlke">Karen L. Mohlke</name><affiliation wicri:level="2"><nlm:aff id="A117">Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Genetics, University of North Carolina, Chapel Hill, North Carolina</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Bergman, Richard N" sort="Bergman, Richard N" uniqKey="Bergman R" first="Richard N" last="Bergman">Richard N. Bergman</name><affiliation wicri:level="2"><nlm:aff id="A118">Diabetes and Obesity Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Diabetes and Obesity Research Institute, Cedars-Sinai Medical Center, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Tuomilehto, Jaakko" sort="Tuomilehto, Jaakko" uniqKey="Tuomilehto J" first="Jaakko" last="Tuomilehto">Jaakko Tuomilehto</name><affiliation wicri:level="1"><nlm:aff id="A27">Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A115">South Ostrobothnia Central Hospital, Seinäjoki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>South Ostrobothnia Central Hospital, Seinäjoki</wicri:regionArea><wicri:noRegion>Seinäjoki</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A119">Red RECAVA Grupo RD06/0014/0015, Hospital Universitario La Paz, Madrid, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Red RECAVA Grupo RD06/0014/0015, Hospital Universitario La Paz, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A120">Centre for Vascular Prevention, Danube-University Krems, Krems, Austria.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Autriche</country><wicri:regionArea>Centre for Vascular Prevention, Danube-University Krems, Krems</wicri:regionArea><wicri:noRegion>Krems</wicri:noRegion></affiliation></author><author><name sortKey="Boehm, Bernhard O" sort="Boehm, Bernhard O" uniqKey="Boehm B" first="Bernhard O" last="Boehm">Bernhard O. Boehm</name><affiliation wicri:level="3"><nlm:aff id="A121">Division of Endocrinology and Diabetes, Department of Internal Medicine, University Medical Centre Ulm, Ulm, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Division of Endocrinology and Diabetes, Department of Internal Medicine, University Medical Centre Ulm, Ulm</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Ulm</settlement></placeName></affiliation></author><author><name sortKey="Gieger, Christian" sort="Gieger, Christian" uniqKey="Gieger C" first="Christian" last="Gieger">Christian Gieger</name><affiliation wicri:level="1"><nlm:aff id="A22">Institute of Genetic Epidemiology, Helmholtz Zentrum Muenchen, Neuherberg, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum Muenchen, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Hveem, Kristian" sort="Hveem, Kristian" uniqKey="Hveem K" first="Kristian" last="Hveem">Kristian Hveem</name><affiliation wicri:level="1"><nlm:aff id="A51">HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Norvège</country><wicri:regionArea>HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger</wicri:regionArea><wicri:noRegion>Levanger</wicri:noRegion></affiliation></author><author><name sortKey="Cauchi, Stephane" sort="Cauchi, Stephane" uniqKey="Cauchi S" first="Stephane" last="Cauchi">Stephane Cauchi</name><affiliation wicri:level="3"><nlm:aff id="A25">CNRS-UMR-8199, Institute of Biology and Lille 2 University, Pasteur Institute, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>CNRS-UMR-8199, Institute of Biology and Lille 2 University, Pasteur Institute, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation></author><author><name sortKey="Froguel, Philippe" sort="Froguel, Philippe" uniqKey="Froguel P" first="Philippe" last="Froguel">Philippe Froguel</name><affiliation wicri:level="3"><nlm:aff id="A25">CNRS-UMR-8199, Institute of Biology and Lille 2 University, Pasteur Institute, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>CNRS-UMR-8199, Institute of Biology and Lille 2 University, Pasteur Institute, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A122">Genomic Medicine, Imperial College London, Hammersmith Hospital, London, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Genomic Medicine, Imperial College London, Hammersmith Hospital, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Baldassarre, Damiano" sort="Baldassarre, Damiano" uniqKey="Baldassarre D" first="Damiano" last="Baldassarre">Damiano Baldassarre</name><affiliation wicri:level="3"><nlm:aff id="A87">Centro Cardiologico Monzino, IRCCS, Milan, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Centro Cardiologico Monzino, IRCCS, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A123">Department of Pharmacological Sciences, University of Milan, Milan, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Department of Pharmacological Sciences, University of Milan, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Tremoli, Elena" sort="Tremoli, Elena" uniqKey="Tremoli E" first="Elena" last="Tremoli">Elena Tremoli</name><affiliation wicri:level="3"><nlm:aff id="A87">Centro Cardiologico Monzino, IRCCS, Milan, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Centro Cardiologico Monzino, IRCCS, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A123">Department of Pharmacological Sciences, University of Milan, Milan, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Department of Pharmacological Sciences, University of Milan, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Humphries, Steve E" sort="Humphries, Steve E" uniqKey="Humphries S" first="Steve E" last="Humphries">Steve E. Humphries</name><affiliation wicri:level="4"><nlm:aff id="A124">Institute of Cardiovascular Science, University College London, London, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Cardiovascular Science, University College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">University College de Londres</orgName></affiliation></author><author><name sortKey="Saleheen, Danish" sort="Saleheen, Danish" uniqKey="Saleheen D" first="Danish" last="Saleheen">Danish Saleheen</name><affiliation wicri:level="4"><nlm:aff id="A10">Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A125">Center for Non-Communicable Diseases Pakistan, Karachi, Pakistan.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pakistan</country><wicri:regionArea>Center for Non-Communicable Diseases Pakistan, Karachi</wicri:regionArea><wicri:noRegion>Karachi</wicri:noRegion></affiliation></author><author><name sortKey="Danesh, John" sort="Danesh, John" uniqKey="Danesh J" first="John" last="Danesh">John Danesh</name><affiliation wicri:level="4"><nlm:aff id="A10">Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Department of Public Health and Primary Care, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Ingelsson, Erik" sort="Ingelsson, Erik" uniqKey="Ingelsson E" first="Erik" last="Ingelsson">Erik Ingelsson</name><affiliation wicri:level="3"><nlm:aff id="A55">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Ripatti, Samuli" sort="Ripatti, Samuli" uniqKey="Ripatti S" first="Samuli" last="Ripatti">Samuli Ripatti</name><affiliation wicri:level="1"><nlm:aff id="A19">Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A58">Institute for Molecular Medicine Finland (FIMM), Helsinki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Institute for Molecular Medicine Finland (FIMM), Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A59">Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Salomaa, Veikko" sort="Salomaa, Veikko" uniqKey="Salomaa V" first="Veikko" last="Salomaa">Veikko Salomaa</name><affiliation wicri:level="1"><nlm:aff id="A59">Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Erbel, Raimund" sort="Erbel, Raimund" uniqKey="Erbel R" first="Raimund" last="Erbel">Raimund Erbel</name><affiliation wicri:level="1"><nlm:aff id="A126">Clinic of Cardiology, West German Heart Centre, University Hospital of Essen, University Duisburg-Essen, Essen, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Clinic of Cardiology, West German Heart Centre, University Hospital of Essen, University Duisburg-Essen, Essen</wicri:regionArea><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author><author><name sortKey="Jockel, Karl Heinz" sort="Jockel, Karl Heinz" uniqKey="Jockel K" first="Karl-Heinz" last="Jöckel">Karl-Heinz Jöckel</name><affiliation wicri:level="1"><nlm:aff id="A24">Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, University Duisburg-Essen, Essen, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, University Duisburg-Essen, Essen</wicri:regionArea><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author><author><name sortKey="Moebus, Susanne" sort="Moebus, Susanne" uniqKey="Moebus S" first="Susanne" last="Moebus">Susanne Moebus</name><affiliation wicri:level="1"><nlm:aff id="A24">Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, University Duisburg-Essen, Essen, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, University Duisburg-Essen, Essen</wicri:regionArea><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author><author><name sortKey="Peters, Annette" sort="Peters, Annette" uniqKey="Peters A" first="Annette" last="Peters">Annette Peters</name><affiliation wicri:level="1"><nlm:aff id="A86">Institute of Epidemiology II, Helmholtz Zentrum Muenchen, Neuherberg, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Institute of Epidemiology II, Helmholtz Zentrum Muenchen, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Illig, Thomas" sort="Illig, Thomas" uniqKey="Illig T" first="Thomas" last="Illig">Thomas Illig</name><affiliation wicri:level="1"><nlm:aff id="A11">Research Unit of Molecular Epidemiology, Helmholtz Zentrum Muenchen, Neuherberg, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Research Unit of Molecular Epidemiology, Helmholtz Zentrum Muenchen, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A127">Hannover Unified Biobank, Hannover Medical School, Hannover, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Hannover Unified Biobank, Hannover Medical School, Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="De Faire, Ulf" sort="De Faire, Ulf" uniqKey="De Faire U" first="Ulf" last="De Faire">Ulf De Faire</name><affiliation wicri:level="3"><nlm:aff id="A70">Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Hamsten, Anders" sort="Hamsten, Anders" uniqKey="Hamsten A" first="Anders" last="Hamsten">Anders Hamsten</name><affiliation wicri:level="3"><nlm:aff id="A8">Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A9">Center for Molecular Medicine, Karolinska University Hospital Solna, Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Center for Molecular Medicine, Karolinska University Hospital Solna, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Morris, Andrew D" sort="Morris, Andrew D" uniqKey="Morris A" first="Andrew D" last="Morris">Andrew D. Morris</name><affiliation wicri:level="1"><nlm:aff id="A65">Diabetes Research Centre, Biomedical Research Institute, University of Dundee, Ninewells Hospital, Dundee, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Diabetes Research Centre, Biomedical Research Institute, University of Dundee, Ninewells Hospital, Dundee</wicri:regionArea><wicri:noRegion>Dundee</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A66">Pharmacogenomics Centre, Biomedical Research Institute, University of Dundee, Ninewells Hospital, Dundee, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Pharmacogenomics Centre, Biomedical Research Institute, University of Dundee, Ninewells Hospital, Dundee</wicri:regionArea><wicri:noRegion>Dundee</wicri:noRegion></affiliation></author><author><name sortKey="Donnelly, Peter J" sort="Donnelly, Peter J" uniqKey="Donnelly P" first="Peter J" last="Donnelly">Peter J. Donnelly</name><affiliation wicri:level="4"><nlm:aff id="A1">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A128">Department of Statistics, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Department of Statistics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Frayling, Timothy M" sort="Frayling, Timothy M" uniqKey="Frayling T" first="Timothy M" last="Frayling">Timothy M. Frayling</name><affiliation wicri:level="1"><nlm:aff id="A53">Genetics of Complex Traits, Institute of Biomedical and Clinical Science, Peninsula Medical School, University of Exeter, Magdalen Road, Exeter, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Genetics of Complex Traits, Institute of Biomedical and Clinical Science, Peninsula Medical School, University of Exeter, Magdalen Road, Exeter</wicri:regionArea><wicri:noRegion>Exeter</wicri:noRegion></affiliation></author><author><name sortKey="Hattersley, Andrew T" sort="Hattersley, Andrew T" uniqKey="Hattersley A" first="Andrew T" last="Hattersley">Andrew T. Hattersley</name><affiliation wicri:level="1"><nlm:aff id="A129">Diabetes Genetics, Institute of Biomedical and Clinical Science, Peninsula Medical School, University of Exeter, Exeter, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Diabetes Genetics, Institute of Biomedical and Clinical Science, Peninsula Medical School, University of Exeter, Exeter</wicri:regionArea><wicri:noRegion>Exeter</wicri:noRegion></affiliation></author><author><name sortKey="Boerwinkle, Eric" sort="Boerwinkle, Eric" uniqKey="Boerwinkle E" first="Eric" last="Boerwinkle">Eric Boerwinkle</name><affiliation wicri:level="2"><nlm:aff id="A130">Human Genetics Center, University of Texas Health Science Center at Houston, Houston, Texas, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Human Genetics Center, University of Texas Health Science Center at Houston, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A131">Human Genome Sequencing Center at Baylor College of Medicine, Houston, Texas, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Human Genome Sequencing Center at Baylor College of Medicine, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Melander, Olle" sort="Melander, Olle" uniqKey="Melander O" first="Olle" last="Melander">Olle Melander</name><affiliation wicri:level="1"><nlm:aff id="A60">Lund University Diabetes Centre, Department of Clinical Science Malmö, Scania University Hospital, Lund University, Malmö, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Lund University Diabetes Centre, Department of Clinical Science Malmö, Scania University Hospital, Lund University, Malmö</wicri:regionArea><wicri:noRegion>Malmö</wicri:noRegion></affiliation></author><author><name sortKey="Kathiresan, Sekar" sort="Kathiresan, Sekar" uniqKey="Kathiresan S" first="Sekar" last="Kathiresan">Sekar Kathiresan</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A5">Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A132">Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Nilsson, Peter M" sort="Nilsson, Peter M" uniqKey="Nilsson P" first="Peter M" last="Nilsson">Peter M. Nilsson</name><affiliation wicri:level="1"><nlm:aff id="A60">Lund University Diabetes Centre, Department of Clinical Science Malmö, Scania University Hospital, Lund University, Malmö, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Lund University Diabetes Centre, Department of Clinical Science Malmö, Scania University Hospital, Lund University, Malmö</wicri:regionArea><wicri:noRegion>Malmö</wicri:noRegion></affiliation></author><author><name sortKey="Deloukas, Panos" sort="Deloukas, Panos" uniqKey="Deloukas P" first="Panos" last="Deloukas">Panos Deloukas</name><affiliation wicri:level="1"><nlm:aff id="A19">Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Thorsteinsdottir, Unnur" sort="Thorsteinsdottir, Unnur" uniqKey="Thorsteinsdottir U" first="Unnur" last="Thorsteinsdottir">Unnur Thorsteinsdottir</name><affiliation wicri:level="1"><nlm:aff id="A7">deCODE Genetics, Reykjavik, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>deCODE Genetics, Reykjavik</wicri:regionArea><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A62">Faculty of Medicine, University of Iceland, Reykjavík, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>Faculty of Medicine, University of Iceland, Reykjavík</wicri:regionArea><wicri:noRegion>Reykjavík</wicri:noRegion></affiliation></author><author><name sortKey="Groop, Leif C" sort="Groop, Leif C" uniqKey="Groop L" first="Leif C" last="Groop">Leif C. Groop</name><affiliation wicri:level="1"><nlm:aff id="A60">Lund University Diabetes Centre, Department of Clinical Science Malmö, Scania University Hospital, Lund University, Malmö, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Lund University Diabetes Centre, Department of Clinical Science Malmö, Scania University Hospital, Lund University, Malmö</wicri:regionArea><wicri:noRegion>Malmö</wicri:noRegion></affiliation></author><author><name sortKey="Stefansson, Kari" sort="Stefansson, Kari" uniqKey="Stefansson K" first="Kari" last="Stefansson">Kari Stefansson</name><affiliation wicri:level="1"><nlm:aff id="A7">deCODE Genetics, Reykjavik, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>deCODE Genetics, Reykjavik</wicri:regionArea><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A62">Faculty of Medicine, University of Iceland, Reykjavík, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>Faculty of Medicine, University of Iceland, Reykjavík</wicri:regionArea><wicri:noRegion>Reykjavík</wicri:noRegion></affiliation></author><author><name sortKey="Hu, Frank" sort="Hu, Frank" uniqKey="Hu F" first="Frank" last="Hu">Frank Hu</name><affiliation wicri:level="2"><nlm:aff id="A46">Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A48">Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Pankow, James S" sort="Pankow, James S" uniqKey="Pankow J" first="James S" last="Pankow">James S. Pankow</name><affiliation wicri:level="2"><nlm:aff id="A133">Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota</wicri:regionArea><placeName><region type="state">Minnesota</region></placeName></affiliation></author><author><name sortKey="Dupuis, Josee" sort="Dupuis, Josee" uniqKey="Dupuis J" first="Josée" last="Dupuis">Josée Dupuis</name><affiliation wicri:level="2"><nlm:aff id="A32">National Heart, Lung, and Blood Institute’s Framingham Heart Study, Framingham, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>National Heart, Lung, and Blood Institute’s Framingham Heart Study, Framingham, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A40">Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Meigs, James B" sort="Meigs, James B" uniqKey="Meigs J" first="James B" last="Meigs">James B. Meigs</name><affiliation wicri:level="2"><nlm:aff id="A6">Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Medicine, Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A134">General Medicine Division, Massachusetts General Hospital, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>General Medicine Division, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Altshuler, David" sort="Altshuler, David" uniqKey="Altshuler D" first="David" last="Altshuler">David Altshuler</name><affiliation wicri:level="2"><nlm:aff id="A2">Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A5">Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A6">Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Medicine, Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A135">Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Genetics, Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A136">Department of Molecular Biology, Harvard Medical School, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Molecular Biology, Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A137">Diabetes Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Diabetes Unit, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Boehnke, Michael" sort="Boehnke, Michael" uniqKey="Boehnke M" first="Michael" last="Boehnke">Michael Boehnke</name><affiliation wicri:level="2"><nlm:aff id="A4">Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Biostatistics, University of Michigan, Ann Arbor, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Mccarthy, Mark I" sort="Mccarthy, Mark I" uniqKey="Mccarthy M" first="Mark I" last="Mccarthy">Mark I. Mccarthy</name><affiliation wicri:level="4"><nlm:aff id="A1">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A12">Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A92">Oxford National Institute for Health Research Biomedical Research Centre, Churchill Hospital, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Oxford National Institute for Health Research Biomedical Research Centre, Churchill Hospital, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region></placeName></affiliation></author></analytic><series><title level="j">Nature genetics</title><idno type="ISSN">1061-4036</idno><idno type="eISSN">1546-1718</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P5">To extend understanding of the genetic architecture and molecular basis of type 2 diabetes (T2D), we conducted a meta-analysis of genetic variants on the Metabochip involving 34,840 cases and 114,981 controls, overwhelmingly of European descent. We identified ten previously unreported T2D susceptibility loci, including two demonstrating sex-differentiated association. Genome-wide analyses of these data are consistent with a long tail of further common variant loci explaining much of the variation in susceptibility to T2D. Exploration of the enlarged set of susceptibility loci implicates several processes, including CREBBP-related transcription, adipocytokine signalling and cell cycle regulation, in diabetes pathogenesis.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Stumvoll, M" uniqKey="Stumvoll M">M Stumvoll</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zeggini, E" uniqKey="Zeggini E">E Zeggini</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kong, A" uniqKey="Kong A">A Kong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Voight, Bf" uniqKey="Voight B">BF Voight</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dupuis, J" uniqKey="Dupuis J">J Dupuis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Qi, L" uniqKey="Qi L">L 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Lage</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rossin, Ej" uniqKey="Rossin E">EJ Rossin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Raychaudhuri, S" uniqKey="Raychaudhuri S">S Raychaudhuri</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Muoio, Dm" uniqKey="Muoio D">DM Muoio</name></author><author><name sortKey="Newgard, Cb" uniqKey="Newgard C">CB Newgard</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gangwisch, Je" uniqKey="Gangwisch J">JE Gangwisch</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Boucher, Bj" uniqKey="Boucher B">BJ Boucher</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Segre, Av" uniqKey="Segre A">AV Segre</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pittas, Ag" uniqKey="Pittas A">AG Pittas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rane, Sg" uniqKey="Rane S">SG Rane</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fiaschi Taesch, Nm" uniqKey="Fiaschi Taesch N">NM Fiaschi-Taesch</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Devlin, B" uniqKey="Devlin B">B Devlin</name></author><author><name sortKey="Roeder, K" uniqKey="Roeder K">K Roeder</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ioannidis, J" uniqKey="Ioannidis J">J Ioannidis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lin, S" uniqKey="Lin S">S Lin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Storey, Jd" uniqKey="Storey J">JD Storey</name></author><author><name sortKey="Tibshirani, R" uniqKey="Tibshirani R">R Tibshirani</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stolerman, Es" uniqKey="Stolerman E">ES Stolerman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stefansson, H" uniqKey="Stefansson H">H Stefansson</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Autriche</li><li>Espagne</li><li>Estonie</li><li>Finlande</li><li>France</li><li>Grèce</li><li>Islande</li><li>Italie</li><li>Norvège</li><li>Pakistan</li><li>Pays-Bas</li><li>Royaume-Uni</li><li>Singapour</li><li>Suisse</li><li>Suède</li><li>États-Unis</li></country><region><li>Angleterre</li><li>Angleterre de l'Est</li><li>Attique (région)</li><li>Bade-Wurtemberg</li><li>Basse-Saxe</li><li>Bavière</li><li>Californie</li><li>Caroline du Nord</li><li>Communauté de Madrid</li><li>District de Cologne</li><li>District de Düsseldorf</li><li>District de Haute-Bavière</li><li>District de Tübingen</li><li>East Middle Sweden</li><li>Grand Londres</li><li>Hauts-de-France</li><li>Hollande-Méridionale</li><li>Hollande-Septentrionale</li><li>Lombardie</li><li>Maryland</li><li>Massachusetts</li><li>Michigan</li><li>Minnesota</li><li>Nord-Pas-de-Calais</li><li>Oxfordshire</li><li>Pays de la Loire</li><li>Pennsylvanie</li><li>Rhénanie-du-Nord-Westphalie</li><li>Svealand</li><li>Texas</li><li>Uusimaa</li><li>Écosse</li><li>État de New York</li></region><settlement><li>Amsterdam</li><li>Athènes</li><li>Bonn</li><li>Cambridge</li><li>Cambridge (Massachusetts)</li><li>Chapel Hill (Caroline du Nord)</li><li>Düsseldorf</li><li>Hanovre</li><li>Helsinki</li><li>Lille</li><li>Londres</li><li>Madrid</li><li>Milan</li><li>Munich</li><li>Nantes</li><li>Oxford</li><li>Rotterdam</li><li>Stockholm</li><li>Ulm</li><li>Uppsala</li><li>Édimbourg</li></settlement><orgName><li>University College de Londres</li><li>Université Harokopio</li><li>Université Harvard</li><li>Université d'Amsterdam</li><li>Université d'Helsinki</li><li>Université d'Oxford</li><li>Université d'Ulm</li><li>Université d'Uppsala</li><li>Université d'Édimbourg</li><li>Université de Cambridge</li><li>Université de Caroline du Nord à Chapel Hill</li><li>Université nationale de Singapour</li></orgName></list><tree><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Morris, Andrew P" sort="Morris, Andrew P" uniqKey="Morris A" first="Andrew P" last="Morris">Andrew P. Morris</name></region><name sortKey="Barroso, Ines" sort="Barroso, Ines" uniqKey="Barroso I" first="Ines" last="Barroso">Ines Barroso</name><name sortKey="Barroso, Ines" sort="Barroso, Ines" uniqKey="Barroso I" first="Ines" last="Barroso">Ines Barroso</name><name sortKey="Barroso, Ines" sort="Barroso, Ines" uniqKey="Barroso I" first="Ines" last="Barroso">Ines Barroso</name><name sortKey="Campbell, Harry" sort="Campbell, Harry" uniqKey="Campbell H" first="Harry" last="Campbell">Harry Campbell</name><name sortKey="Campbell, Harry" sort="Campbell, Harry" uniqKey="Campbell H" first="Harry" last="Campbell">Harry Campbell</name><name sortKey="Danesh, John" sort="Danesh, John" uniqKey="Danesh J" first="John" last="Danesh">John Danesh</name><name sortKey="Deloukas, Panos" sort="Deloukas, Panos" uniqKey="Deloukas P" first="Panos" last="Deloukas">Panos Deloukas</name><name sortKey="Dimas, Antigone S" sort="Dimas, Antigone S" uniqKey="Dimas A" first="Antigone S" last="Dimas">Antigone S. Dimas</name><name sortKey="Doney, Alex S F" sort="Doney, Alex S F" uniqKey="Doney A" first="Alex S F" last="Doney">Alex S F. Doney</name><name sortKey="Doney, Alex S F" sort="Doney, Alex S F" uniqKey="Doney A" first="Alex S F" last="Doney">Alex S F. Doney</name><name sortKey="Donnelly, Peter J" sort="Donnelly, Peter J" uniqKey="Donnelly P" first="Peter J" last="Donnelly">Peter J. Donnelly</name><name sortKey="Donnelly, Peter J" sort="Donnelly, Peter J" uniqKey="Donnelly P" first="Peter J" last="Donnelly">Peter J. Donnelly</name><name sortKey="Edkins, Sarah" sort="Edkins, Sarah" uniqKey="Edkins S" first="Sarah" last="Edkins">Sarah Edkins</name><name sortKey="Ferreira, Teresa" sort="Ferreira, Teresa" uniqKey="Ferreira T" first="Teresa" last="Ferreira">Teresa Ferreira</name><name sortKey="Forouhi, Nita G" sort="Forouhi, Nita G" uniqKey="Forouhi N" first="Nita G" last="Forouhi">Nita G. Forouhi</name><name sortKey="Fraser, Ross M" sort="Fraser, Ross M" uniqKey="Fraser R" first="Ross M" last="Fraser">Ross M. Fraser</name><name sortKey="Frayling, Timothy M" sort="Frayling, Timothy M" uniqKey="Frayling T" first="Timothy M" last="Frayling">Timothy M. Frayling</name><name sortKey="Froguel, Philippe" sort="Froguel, Philippe" uniqKey="Froguel P" first="Philippe" last="Froguel">Philippe Froguel</name><name sortKey="Groves, Christopher J" sort="Groves, Christopher J" uniqKey="Groves C" first="Christopher J" last="Groves">Christopher J. Groves</name><name sortKey="Hattersley, Andrew T" sort="Hattersley, Andrew T" uniqKey="Hattersley A" first="Andrew T" last="Hattersley">Andrew T. Hattersley</name><name sortKey="Humphries, Steve E" sort="Humphries, Steve E" uniqKey="Humphries S" first="Steve E" last="Humphries">Steve E. Humphries</name><name sortKey="Hunt, Sarah E" sort="Hunt, Sarah E" uniqKey="Hunt S" first="Sarah E" last="Hunt">Sarah E. Hunt</name><name sortKey="Kanoni, Stavroula" sort="Kanoni, Stavroula" uniqKey="Kanoni S" first="Stavroula" last="Kanoni">Stavroula Kanoni</name><name sortKey="Khan, Hassan" sort="Khan, Hassan" uniqKey="Khan H" first="Hassan" last="Khan">Hassan Khan</name><name sortKey="Khaw, Kay Tee" sort="Khaw, Kay Tee" uniqKey="Khaw K" first="Kay-Tee" last="Khaw">Kay-Tee Khaw</name><name sortKey="Kumar, Ashish" sort="Kumar, Ashish" uniqKey="Kumar A" first="Ashish" last="Kumar">Ashish Kumar</name><name sortKey="Lagou, Vasiliki" sort="Lagou, Vasiliki" uniqKey="Lagou V" first="Vasiliki" last="Lagou">Vasiliki Lagou</name><name sortKey="Langenberg, Claudia" sort="Langenberg, Claudia" uniqKey="Langenberg C" first="Claudia" last="Langenberg">Claudia Langenberg</name><name sortKey="Langford, Cordelia" sort="Langford, Cordelia" uniqKey="Langford C" first="Cordelia" last="Langford">Cordelia Langford</name><name sortKey="Lindgren, Cecilia M" sort="Lindgren, Cecilia M" uniqKey="Lindgren C" first="Cecilia M" last="Lindgren">Cecilia M. Lindgren</name><name sortKey="Loos, Ruth J F" sort="Loos, Ruth J F" uniqKey="Loos R" first="Ruth J F" last="Loos">Ruth J F. Loos</name><name sortKey="Luan, Jian An" sort="Luan, Jian An" uniqKey="Luan J" first="Jian'An" last="Luan">Jian'An Luan</name><name sortKey="Mahajan, Anubha" sort="Mahajan, Anubha" uniqKey="Mahajan A" first="Anubha" last="Mahajan">Anubha Mahajan</name><name sortKey="Mccarthy, Mark I" sort="Mccarthy, Mark I" uniqKey="Mccarthy M" first="Mark I" last="Mccarthy">Mark I. Mccarthy</name><name sortKey="Mccarthy, Mark I" sort="Mccarthy, Mark I" uniqKey="Mccarthy M" first="Mark I" last="Mccarthy">Mark I. Mccarthy</name><name sortKey="Mccarthy, Mark I" sort="Mccarthy, Mark I" uniqKey="Mccarthy M" first="Mark I" last="Mccarthy">Mark I. Mccarthy</name><name sortKey="Mirza, Ghazala" sort="Mirza, Ghazala" uniqKey="Mirza G" first="Ghazala" last="Mirza">Ghazala Mirza</name><name sortKey="Morris, Andrew D" sort="Morris, Andrew D" uniqKey="Morris A" first="Andrew D" last="Morris">Andrew D. Morris</name><name sortKey="Morris, Andrew D" sort="Morris, Andrew D" uniqKey="Morris A" first="Andrew D" last="Morris">Andrew D. Morris</name><name sortKey="Owen, Katharine R" sort="Owen, Katharine R" uniqKey="Owen K" first="Katharine R" last="Owen">Katharine R. Owen</name><name sortKey="Owen, Katharine R" sort="Owen, Katharine R" uniqKey="Owen K" first="Katharine R" last="Owen">Katharine R. Owen</name><name sortKey="Palmer, Colin N A" sort="Palmer, Colin N A" uniqKey="Palmer C" first="Colin N A" last="Palmer">Colin N A. Palmer</name><name sortKey="Palmer, Colin N A" sort="Palmer, Colin N A" uniqKey="Palmer C" first="Colin N A" last="Palmer">Colin N A. Palmer</name><name sortKey="Peltonen, Leena" sort="Peltonen, Leena" uniqKey="Peltonen L" first="Leena" last="Peltonen">Leena Peltonen</name><name sortKey="Perry, John Rb" sort="Perry, John Rb" uniqKey="Perry J" first="John Rb" last="Perry">John Rb Perry</name><name sortKey="Perry, John Rb" sort="Perry, John Rb" uniqKey="Perry J" first="John Rb" last="Perry">John Rb Perry</name><name sortKey="Potter, Simon" sort="Potter, Simon" uniqKey="Potter S" first="Simon" last="Potter">Simon Potter</name><name sortKey="Price, Jackie F" sort="Price, Jackie F" uniqKey="Price J" first="Jackie F" last="Price">Jackie F. Price</name><name sortKey="Prokopenko, Inga" sort="Prokopenko, Inga" uniqKey="Prokopenko I" first="Inga" last="Prokopenko">Inga Prokopenko</name><name sortKey="Prokopenko, Inga" sort="Prokopenko, Inga" uniqKey="Prokopenko I" first="Inga" last="Prokopenko">Inga Prokopenko</name><name sortKey="Rayner, N William" sort="Rayner, N William" uniqKey="Rayner N" first="N William" last="Rayner">N William Rayner</name><name sortKey="Rayner, N William" sort="Rayner, N William" uniqKey="Rayner N" first="N William" last="Rayner">N William Rayner</name><name sortKey="Ripatti, Samuli" sort="Ripatti, Samuli" uniqKey="Ripatti S" first="Samuli" last="Ripatti">Samuli Ripatti</name><name sortKey="Robertson, Neil" sort="Robertson, Neil" uniqKey="Robertson N" first="Neil" last="Robertson">Neil Robertson</name><name sortKey="Robertson, Neil" sort="Robertson, Neil" uniqKey="Robertson N" first="Neil" last="Robertson">Neil Robertson</name><name sortKey="Saleheen, Danish" sort="Saleheen, Danish" uniqKey="Saleheen D" first="Danish" last="Saleheen">Danish Saleheen</name><name sortKey="Shah, Sonia" sort="Shah, Sonia" uniqKey="Shah S" first="Sonia" last="Shah">Sonia Shah</name><name sortKey="Stirrups, Kathleen" sort="Stirrups, Kathleen" uniqKey="Stirrups K" first="Kathleen" last="Stirrups">Kathleen Stirrups</name><name sortKey="Trakalo, Joseph" sort="Trakalo, Joseph" uniqKey="Trakalo J" first="Joseph" last="Trakalo">Joseph Trakalo</name><name sortKey="Wareham, Nicholas J" sort="Wareham, Nicholas J" uniqKey="Wareham N" first="Nicholas J" last="Wareham">Nicholas J. Wareham</name><name sortKey="Wilson, James F" sort="Wilson, James F" uniqKey="Wilson J" first="James F" last="Wilson">James F. Wilson</name><name sortKey="Wilson, James F" sort="Wilson, James F" uniqKey="Wilson J" first="James F" last="Wilson">James F. Wilson</name><name sortKey="Wiltshire, Steven" sort="Wiltshire, Steven" uniqKey="Wiltshire S" first="Steven" last="Wiltshire">Steven Wiltshire</name><name sortKey="Wood, Andrew R" sort="Wood, Andrew R" uniqKey="Wood A" first="Andrew R" last="Wood">Andrew R. Wood</name><name sortKey="Zabaneh, Delilah" sort="Zabaneh, Delilah" uniqKey="Zabaneh D" first="Delilah" last="Zabaneh">Delilah Zabaneh</name><name sortKey="Zeggini, Eleftheria" sort="Zeggini, Eleftheria" uniqKey="Zeggini E" first="Eleftheria" last="Zeggini">Eleftheria Zeggini</name></country><country name="États-Unis"><region name="Massachusetts"><name sortKey="Voight, Benjamin F" sort="Voight, Benjamin F" uniqKey="Voight B" first="Benjamin F" last="Voight">Benjamin F. Voight</name></region><name sortKey="Abecasis, Goncalo R" sort="Abecasis, Goncalo R" uniqKey="Abecasis G" first="Goncalo R" last="Abecasis">Goncalo R. Abecasis</name><name sortKey="Altshuler, David" sort="Altshuler, David" uniqKey="Altshuler D" first="David" last="Altshuler">David Altshuler</name><name sortKey="Altshuler, David" sort="Altshuler, David" uniqKey="Altshuler D" first="David" last="Altshuler">David Altshuler</name><name sortKey="Altshuler, David" sort="Altshuler, David" uniqKey="Altshuler D" first="David" last="Altshuler">David Altshuler</name><name sortKey="Altshuler, David" sort="Altshuler, David" uniqKey="Altshuler D" first="David" last="Altshuler">David Altshuler</name><name sortKey="Altshuler, David" sort="Altshuler, David" uniqKey="Altshuler D" first="David" last="Altshuler">David Altshuler</name><name sortKey="Altshuler, David" sort="Altshuler, David" uniqKey="Altshuler D" first="David" last="Altshuler">David Altshuler</name><name sortKey="Bergman, Richard N" sort="Bergman, Richard N" uniqKey="Bergman R" first="Richard N" last="Bergman">Richard N. Bergman</name><name sortKey="Boehnke, Michael" sort="Boehnke, Michael" uniqKey="Boehnke M" first="Michael" last="Boehnke">Michael Boehnke</name><name sortKey="Boerwinkle, Eric" sort="Boerwinkle, Eric" uniqKey="Boerwinkle E" first="Eric" last="Boerwinkle">Eric Boerwinkle</name><name sortKey="Boerwinkle, Eric" sort="Boerwinkle, Eric" uniqKey="Boerwinkle E" first="Eric" last="Boerwinkle">Eric Boerwinkle</name><name sortKey="Bonnycastle, Lori L" sort="Bonnycastle, Lori L" uniqKey="Bonnycastle L" first="Lori L" last="Bonnycastle">Lori L. Bonnycastle</name><name sortKey="Burtt, Noel" sort="Burtt, Noel" uniqKey="Burtt N" first="Noël" last="Burtt">Noël Burtt</name><name sortKey="Carey, Jason" sort="Carey, Jason" uniqKey="Carey J" first="Jason" last="Carey">Jason Carey</name><name sortKey="Chen, Han" sort="Chen, Han" uniqKey="Chen H" first="Han" last="Chen">Han Chen</name><name sortKey="Chines, Peter S" sort="Chines, Peter S" uniqKey="Chines P" first="Peter S" last="Chines">Peter S. Chines</name><name sortKey="Collins, Francis S" sort="Collins, Francis S" uniqKey="Collins F" first="Francis S" last="Collins">Francis S. Collins</name><name sortKey="Cornelis, Marilyn C" sort="Cornelis, Marilyn C" uniqKey="Cornelis M" first="Marilyn C" last="Cornelis">Marilyn C. Cornelis</name><name sortKey="Couper, David J" sort="Couper, David J" uniqKey="Couper D" first="David J" last="Couper">David J. Couper</name><name sortKey="Crenshaw, Andrew T" sort="Crenshaw, Andrew T" uniqKey="Crenshaw A" first="Andrew T" last="Crenshaw">Andrew T. Crenshaw</name><name sortKey="Dupuis, Josee" sort="Dupuis, Josee" uniqKey="Dupuis J" first="Josée" last="Dupuis">Josée Dupuis</name><name sortKey="Dupuis, Josee" sort="Dupuis, Josee" uniqKey="Dupuis J" first="Josée" last="Dupuis">Josée Dupuis</name><name sortKey="Florez, Jose C" sort="Florez, Jose C" uniqKey="Florez J" first="Jose C" last="Florez">Jose C. Florez</name><name sortKey="Florez, Jose C" sort="Florez, Jose C" uniqKey="Florez J" first="Jose C" last="Florez">Jose C. Florez</name><name sortKey="Florez, Jose C" sort="Florez, Jose C" uniqKey="Florez J" first="Jose C" last="Florez">Jose C. Florez</name><name sortKey="Florez, Jose C" sort="Florez, Jose C" uniqKey="Florez J" first="Jose C" last="Florez">Jose C. Florez</name><name sortKey="Fontanillas, Pierre" sort="Fontanillas, Pierre" uniqKey="Fontanillas P" first="Pierre" last="Fontanillas">Pierre Fontanillas</name><name sortKey="Fox, Caroline" sort="Fox, Caroline" uniqKey="Fox C" first="Caroline" last="Fox">Caroline Fox</name><name sortKey="Fox, Caroline" sort="Fox, Caroline" uniqKey="Fox C" first="Caroline" last="Fox">Caroline Fox</name><name sortKey="Grant, George B" sort="Grant, George B" uniqKey="Grant G" first="George B" last="Grant">George B. Grant</name><name sortKey="Guiducci, Candace" sort="Guiducci, Candace" uniqKey="Guiducci C" first="Candace" last="Guiducci">Candace Guiducci</name><name sortKey="Hu, Frank" sort="Hu, Frank" uniqKey="Hu F" first="Frank" last="Hu">Frank Hu</name><name sortKey="Hu, Frank" sort="Hu, Frank" uniqKey="Hu F" first="Frank" last="Hu">Frank Hu</name><name sortKey="Hunter, David J" sort="Hunter, David J" uniqKey="Hunter D" first="David J" last="Hunter">David J. Hunter</name><name sortKey="Hunter, David J" sort="Hunter, David J" uniqKey="Hunter D" first="David J" last="Hunter">David J. Hunter</name><name sortKey="Hunter, David J" sort="Hunter, David J" uniqKey="Hunter D" first="David J" last="Hunter">David J. Hunter</name><name sortKey="Jackson, Anne U" sort="Jackson, Anne U" uniqKey="Jackson A" first="Anne U" last="Jackson">Anne U. Jackson</name><name sortKey="Johnson, Andrew D" sort="Johnson, Andrew D" uniqKey="Johnson A" first="Andrew D" last="Johnson">Andrew D. Johnson</name><name sortKey="Kang, Hyun Min" sort="Kang, Hyun Min" uniqKey="Kang H" first="Hyun Min" last="Kang">Hyun Min Kang</name><name sortKey="Kao, Wen Hong L" sort="Kao, Wen Hong L" uniqKey="Kao W" first="Wen Hong L" last="Kao">Wen Hong L. Kao</name><name sortKey="Kathiresan, Sekar" sort="Kathiresan, Sekar" uniqKey="Kathiresan S" first="Sekar" last="Kathiresan">Sekar Kathiresan</name><name sortKey="Kathiresan, Sekar" sort="Kathiresan, Sekar" uniqKey="Kathiresan S" first="Sekar" last="Kathiresan">Sekar Kathiresan</name><name sortKey="Kathiresan, Sekar" sort="Kathiresan, Sekar" uniqKey="Kathiresan S" first="Sekar" last="Kathiresan">Sekar Kathiresan</name><name sortKey="Kraft, Peter" sort="Kraft, Peter" uniqKey="Kraft P" first="Peter" last="Kraft">Peter Kraft</name><name sortKey="Kraft, Peter" sort="Kraft, Peter" uniqKey="Kraft P" first="Peter" last="Kraft">Peter Kraft</name><name sortKey="Li, Man" sort="Li, Man" uniqKey="Li M" first="Man" last="Li">Man Li</name><name sortKey="Liu, Ching Ti" sort="Liu, Ching Ti" uniqKey="Liu C" first="Ching-Ti" last="Liu">Ching-Ti Liu</name><name sortKey="Loos, Ruth J F" sort="Loos, Ruth J F" uniqKey="Loos R" first="Ruth J F" last="Loos">Ruth J F. Loos</name><name sortKey="Loos, Ruth J F" sort="Loos, Ruth J F" uniqKey="Loos R" first="Ruth J F" last="Loos">Ruth J F. Loos</name><name sortKey="Loos, Ruth J F" sort="Loos, Ruth J F" uniqKey="Loos R" first="Ruth J F" last="Loos">Ruth J F. Loos</name><name sortKey="Meigs, James B" sort="Meigs, James B" uniqKey="Meigs J" first="James B" last="Meigs">James B. Meigs</name><name sortKey="Meigs, James B" sort="Meigs, James B" uniqKey="Meigs J" first="James B" last="Meigs">James B. Meigs</name><name sortKey="Mohlke, Karen L" sort="Mohlke, Karen L" uniqKey="Mohlke K" first="Karen L" last="Mohlke">Karen L. Mohlke</name><name sortKey="Pankow, James S" sort="Pankow, James S" uniqKey="Pankow J" first="James S" last="Pankow">James S. Pankow</name><name sortKey="Parkin, Melissa" sort="Parkin, Melissa" uniqKey="Parkin M" first="Melissa" last="Parkin">Melissa Parkin</name><name sortKey="Peltonen, Leena" sort="Peltonen, Leena" uniqKey="Peltonen L" first="Leena" last="Peltonen">Leena Peltonen</name><name sortKey="Qi, Lu" sort="Qi, Lu" uniqKey="Qi L" first="Lu" last="Qi">Lu Qi</name><name sortKey="Qi, Lu" sort="Qi, Lu" uniqKey="Qi L" first="Lu" last="Qi">Lu Qi</name><name sortKey="Raychaudhuri, Soumya" sort="Raychaudhuri, Soumya" uniqKey="Raychaudhuri S" first="Soumya" last="Raychaudhuri">Soumya Raychaudhuri</name><name sortKey="Raychaudhuri, Soumya" sort="Raychaudhuri, Soumya" uniqKey="Raychaudhuri S" first="Soumya" last="Raychaudhuri">Soumya Raychaudhuri</name><name sortKey="Raychaudhuri, Soumya" sort="Raychaudhuri, Soumya" uniqKey="Raychaudhuri S" first="Soumya" last="Raychaudhuri">Soumya Raychaudhuri</name><name sortKey="Rossin, Elizabeth J" sort="Rossin, Elizabeth J" uniqKey="Rossin E" first="Elizabeth J" last="Rossin">Elizabeth J. Rossin</name><name sortKey="Rossin, Elizabeth J" sort="Rossin, Elizabeth J" uniqKey="Rossin E" first="Elizabeth J" last="Rossin">Elizabeth J. Rossin</name><name sortKey="Rossin, Elizabeth J" sort="Rossin, Elizabeth J" uniqKey="Rossin E" first="Elizabeth J" last="Rossin">Elizabeth J. Rossin</name><name sortKey="Rossin, Elizabeth J" sort="Rossin, Elizabeth J" uniqKey="Rossin E" first="Elizabeth J" last="Rossin">Elizabeth J. Rossin</name><name sortKey="Rybin, Denis" sort="Rybin, Denis" uniqKey="Rybin D" first="Denis" last="Rybin">Denis Rybin</name><name sortKey="Scott, Laura J" sort="Scott, Laura J" uniqKey="Scott L" first="Laura J" last="Scott">Laura J. Scott</name><name sortKey="Segre, Ayellet V" sort="Segre, Ayellet V" uniqKey="Segre A" first="Ayellet V" last="Segrè">Ayellet V. Segrè</name><name sortKey="Segre, Ayellet V" sort="Segre, Ayellet V" uniqKey="Segre A" first="Ayellet V" last="Segrè">Ayellet V. Segrè</name><name sortKey="Segre, Ayellet V" sort="Segre, Ayellet V" uniqKey="Segre A" first="Ayellet V" last="Segrè">Ayellet V. Segrè</name><name sortKey="Shuldiner, Alan R" sort="Shuldiner, Alan R" uniqKey="Shuldiner A" first="Alan R" last="Shuldiner">Alan R. Shuldiner</name><name sortKey="Shuldiner, Alan R" sort="Shuldiner, Alan R" uniqKey="Shuldiner A" first="Alan R" last="Shuldiner">Alan R. Shuldiner</name><name sortKey="Shuldiner, Alan R" sort="Shuldiner, Alan R" uniqKey="Shuldiner A" first="Alan R" last="Shuldiner">Alan R. Shuldiner</name><name sortKey="Stringham, Heather M" sort="Stringham, Heather M" uniqKey="Stringham H" first="Heather M" last="Stringham">Heather M. Stringham</name><name sortKey="Sun, Qi" sort="Sun, Qi" uniqKey="Sun Q" first="Qi" last="Sun">Qi Sun</name><name sortKey="Sun, Qi" sort="Sun, Qi" uniqKey="Sun Q" first="Qi" last="Sun">Qi Sun</name><name sortKey="Teslovich, Tanya M" sort="Teslovich, Tanya M" uniqKey="Teslovich T" first="Tanya M" last="Teslovich">Tanya M. Teslovich</name><name sortKey="Van Dam, Rob M" sort="Van Dam, Rob M" uniqKey="Van Dam R" first="Rob M" last="Van Dam">Rob M. Van Dam</name><name sortKey="Vedantam, Sailaja" sort="Vedantam, Sailaja" uniqKey="Vedantam S" first="Sailaja" last="Vedantam">Sailaja Vedantam</name><name sortKey="Vedantam, Sailaja" sort="Vedantam, Sailaja" uniqKey="Vedantam S" first="Sailaja" last="Vedantam">Sailaja Vedantam</name><name sortKey="Voight, Benjamin F" sort="Voight, Benjamin F" uniqKey="Voight B" first="Benjamin F" last="Voight">Benjamin F. Voight</name><name sortKey="Winckler, Wendy" sort="Winckler, Wendy" uniqKey="Winckler W" first="Wendy" last="Winckler">Wendy Winckler</name></country><country name="Islande"><noRegion><name sortKey="Steinthorsdottir, Valgerdur" sort="Steinthorsdottir, Valgerdur" uniqKey="Steinthorsdottir V" first="Valgerdur" last="Steinthorsdottir">Valgerdur Steinthorsdottir</name></noRegion><name sortKey="Benediktsson, Rafn" sort="Benediktsson, Rafn" uniqKey="Benediktsson R" first="Rafn" last="Benediktsson">Rafn Benediktsson</name><name sortKey="Benediktsson, Rafn" sort="Benediktsson, Rafn" uniqKey="Benediktsson R" first="Rafn" last="Benediktsson">Rafn Benediktsson</name><name sortKey="Emilsson, Valur" sort="Emilsson, Valur" uniqKey="Emilsson V" first="Valur" last="Emilsson">Valur Emilsson</name><name sortKey="Hreidarsson, Astradur B" sort="Hreidarsson, Astradur B" uniqKey="Hreidarsson A" first="Astradur B" last="Hreidarsson">Astradur B. Hreidarsson</name><name sortKey="Kong, Augustine" sort="Kong, Augustine" uniqKey="Kong A" first="Augustine" last="Kong">Augustine Kong</name><name sortKey="Sigur Sson, Gunnar" sort="Sigur Sson, Gunnar" uniqKey="Sigur Sson G" first="Gunnar" last="Sigur Sson">Gunnar Sigur Sson</name><name sortKey="Sigur Sson, Gunnar" sort="Sigur Sson, Gunnar" uniqKey="Sigur Sson G" first="Gunnar" last="Sigur Sson">Gunnar Sigur Sson</name><name sortKey="Stefansson, Kari" sort="Stefansson, Kari" uniqKey="Stefansson K" first="Kari" last="Stefansson">Kari Stefansson</name><name sortKey="Stefansson, Kari" sort="Stefansson, Kari" uniqKey="Stefansson K" first="Kari" last="Stefansson">Kari Stefansson</name><name sortKey="Thorleifsson, Gudmar" sort="Thorleifsson, Gudmar" uniqKey="Thorleifsson G" first="Gudmar" last="Thorleifsson">Gudmar Thorleifsson</name><name sortKey="Thorsteinsdottir, Unnur" sort="Thorsteinsdottir, Unnur" uniqKey="Thorsteinsdottir U" first="Unnur" last="Thorsteinsdottir">Unnur Thorsteinsdottir</name><name sortKey="Thorsteinsdottir, Unnur" sort="Thorsteinsdottir, Unnur" uniqKey="Thorsteinsdottir U" first="Unnur" last="Thorsteinsdottir">Unnur Thorsteinsdottir</name></country><country name="Suède"><region name="Svealand"><name sortKey="Strawbridge, Rona J" sort="Strawbridge, Rona J" uniqKey="Strawbridge R" first="Rona J" last="Strawbridge">Rona J. Strawbridge</name></region><name sortKey="Almgren, Peter" sort="Almgren, Peter" uniqKey="Almgren P" first="Peter" last="Almgren">Peter Almgren</name><name sortKey="De Faire, Ulf" sort="De Faire, Ulf" uniqKey="De Faire U" first="Ulf" last="De Faire">Ulf De Faire</name><name sortKey="Dorkhan, Mozhgan" sort="Dorkhan, Mozhgan" uniqKey="Dorkhan M" first="Mozhgan" last="Dorkhan">Mozhgan Dorkhan</name><name sortKey="Gertow, Karl" sort="Gertow, Karl" uniqKey="Gertow K" first="Karl" last="Gertow">Karl Gertow</name><name sortKey="Gertow, Karl" sort="Gertow, Karl" uniqKey="Gertow K" first="Karl" last="Gertow">Karl Gertow</name><name sortKey="Gigante, Bruna" sort="Gigante, Bruna" uniqKey="Gigante B" first="Bruna" last="Gigante">Bruna Gigante</name><name sortKey="Groop, Leif C" sort="Groop, Leif C" uniqKey="Groop L" first="Leif C" last="Groop">Leif C. Groop</name><name sortKey="Hamsten, Anders" sort="Hamsten, Anders" uniqKey="Hamsten A" first="Anders" last="Hamsten">Anders Hamsten</name><name sortKey="Hamsten, Anders" sort="Hamsten, Anders" uniqKey="Hamsten A" first="Anders" last="Hamsten">Anders Hamsten</name><name sortKey="Ingelsson, Erik" sort="Ingelsson, Erik" uniqKey="Ingelsson E" first="Erik" last="Ingelsson">Erik Ingelsson</name><name sortKey="Jonsson, Anna" sort="Jonsson, Anna" uniqKey="Jonsson A" first="Anna" last="Jonsson">Anna Jonsson</name><name sortKey="Kravic, Jasmina" sort="Kravic, Jasmina" uniqKey="Kravic J" first="Jasmina" last="Kravic">Jasmina Kravic</name><name sortKey="Leander, Karin" sort="Leander, Karin" uniqKey="Leander K" first="Karin" last="Leander">Karin Leander</name><name sortKey="Lind, Lars" sort="Lind, Lars" uniqKey="Lind L" first="Lars" last="Lind">Lars Lind</name><name sortKey="Lindholm, Eero" sort="Lindholm, Eero" uniqKey="Lindholm E" first="Eero" last="Lindholm">Eero Lindholm</name><name sortKey="Lyssenko, Valeriya" sort="Lyssenko, Valeriya" uniqKey="Lyssenko V" first="Valeriya" last="Lyssenko">Valeriya Lyssenko</name><name sortKey="Melander, Olle" sort="Melander, Olle" uniqKey="Melander O" first="Olle" last="Melander">Olle Melander</name><name sortKey="Nilsson, Peter M" sort="Nilsson, Peter M" uniqKey="Nilsson P" first="Peter M" last="Nilsson">Peter M. Nilsson</name><name sortKey="Pedersen, Nancy L" sort="Pedersen, Nancy L" uniqKey="Pedersen N" first="Nancy L" last="Pedersen">Nancy L. Pedersen</name><name sortKey="Rehnberg, Emil" sort="Rehnberg, Emil" uniqKey="Rehnberg E" first="Emil" last="Rehnberg">Emil Rehnberg</name><name sortKey="Sennblad, Bengt" sort="Sennblad, Bengt" uniqKey="Sennblad B" first="Bengt" last="Sennblad">Bengt Sennblad</name><name sortKey="Sennblad, Bengt" sort="Sennblad, Bengt" uniqKey="Sennblad B" first="Bengt" last="Sennblad">Bengt Sennblad</name><name sortKey="Silveira, Angela" sort="Silveira, Angela" uniqKey="Silveira A" first="Angela" last="Silveira">Angela Silveira</name><name sortKey="Silveira, Angela" sort="Silveira, Angela" uniqKey="Silveira A" first="Angela" last="Silveira">Angela Silveira</name><name sortKey="Strawbridge, Rona J" sort="Strawbridge, Rona J" uniqKey="Strawbridge R" first="Rona J" last="Strawbridge">Rona J. Strawbridge</name><name sortKey="Syv Nen, Ann Christine" sort="Syv Nen, Ann Christine" uniqKey="Syv Nen A" first="Ann-Christine" last="Syv Nen">Ann-Christine Syv Nen</name></country><country name="Allemagne"><noRegion><name sortKey="Grallert, Harald" sort="Grallert, Harald" uniqKey="Grallert H" first="Harald" last="Grallert">Harald Grallert</name></noRegion><name sortKey="Boehm, Bernhard O" sort="Boehm, Bernhard O" uniqKey="Boehm B" first="Bernhard O" last="Boehm">Bernhard O. Boehm</name><name sortKey="Erbel, Raimund" sort="Erbel, Raimund" uniqKey="Erbel R" first="Raimund" last="Erbel">Raimund Erbel</name><name sortKey="Gieger, Christian" sort="Gieger, Christian" uniqKey="Gieger C" first="Christian" last="Gieger">Christian Gieger</name><name sortKey="Herder, Christian" sort="Herder, Christian" uniqKey="Herder C" first="Christian" last="Herder">Christian Herder</name><name sortKey="Illig, Thomas" sort="Illig, Thomas" uniqKey="Illig T" first="Thomas" last="Illig">Thomas Illig</name><name sortKey="Illig, Thomas" sort="Illig, Thomas" uniqKey="Illig T" first="Thomas" last="Illig">Thomas Illig</name><name sortKey="Jockel, Karl Heinz" sort="Jockel, Karl Heinz" uniqKey="Jockel K" first="Karl-Heinz" last="Jöckel">Karl-Heinz Jöckel</name><name sortKey="Klopp, Norman" sort="Klopp, Norman" uniqKey="Klopp N" first="Norman" last="Klopp">Norman Klopp</name><name sortKey="Meyer, Julia" sort="Meyer, Julia" uniqKey="Meyer J" first="Julia" last="Meyer">Julia Meyer</name><name sortKey="Moebus, Susanne" sort="Moebus, Susanne" uniqKey="Moebus S" first="Susanne" last="Moebus">Susanne Moebus</name><name sortKey="Muhleisen, Thomas W" sort="Muhleisen, Thomas W" uniqKey="Muhleisen T" first="Thomas W" last="Mühleisen">Thomas W. Mühleisen</name><name sortKey="Muhleisen, Thomas W" sort="Muhleisen, Thomas W" uniqKey="Muhleisen T" first="Thomas W" last="Mühleisen">Thomas W. Mühleisen</name><name sortKey="Muller Nurasyid, Martina" sort="Muller Nurasyid, Martina" uniqKey="Muller Nurasyid M" first="Martina" last="Müller-Nurasyid">Martina Müller-Nurasyid</name><name sortKey="Muller Nurasyid, Martina" sort="Muller Nurasyid, Martina" uniqKey="Muller Nurasyid M" first="Martina" last="Müller-Nurasyid">Martina Müller-Nurasyid</name><name sortKey="Muller Nurasyid, Martina" sort="Muller Nurasyid, Martina" uniqKey="Muller Nurasyid M" first="Martina" last="Müller-Nurasyid">Martina Müller-Nurasyid</name><name sortKey="Nothen, Markus M" sort="Nothen, Markus M" uniqKey="Nothen M" first="Markus M" last="Nöthen">Markus M. Nöthen</name><name sortKey="Nothen, Markus M" sort="Nothen, Markus M" uniqKey="Nothen M" first="Markus M" last="Nöthen">Markus M. Nöthen</name><name sortKey="Pechlivanis, Sonali" sort="Pechlivanis, Sonali" uniqKey="Pechlivanis S" first="Sonali" last="Pechlivanis">Sonali Pechlivanis</name><name sortKey="Peters, Annette" sort="Peters, Annette" uniqKey="Peters A" first="Annette" last="Peters">Annette Peters</name><name sortKey="Rathmann, Wolfgang" sort="Rathmann, Wolfgang" uniqKey="Rathmann W" first="Wolfgang" last="Rathmann">Wolfgang Rathmann</name><name sortKey="Roden, Michael" sort="Roden, Michael" uniqKey="Roden M" first="Michael" last="Roden">Michael Roden</name><name sortKey="Roden, Michael" sort="Roden, Michael" uniqKey="Roden M" first="Michael" last="Roden">Michael Roden</name><name sortKey="Steinbach, Gerald" sort="Steinbach, Gerald" uniqKey="Steinbach G" first="Gerald" last="Steinbach">Gerald Steinbach</name><name sortKey="Thorand, Barbara" sort="Thorand, Barbara" uniqKey="Thorand B" first="Barbara" last="Thorand">Barbara Thorand</name><name sortKey="Wennauer, Roman" sort="Wennauer, Roman" uniqKey="Wennauer R" first="Roman" last="Wennauer">Roman Wennauer</name></country><country name="France"><region name="Pays de la Loire"><name sortKey="Dina, Christian" sort="Dina, Christian" uniqKey="Dina C" first="Christian" last="Dina">Christian Dina</name></region><name sortKey="Balkau, Beverley" sort="Balkau, Beverley" uniqKey="Balkau B" first="Beverley" last="Balkau">Beverley Balkau</name><name sortKey="Balkau, Beverley" sort="Balkau, Beverley" uniqKey="Balkau B" first="Beverley" last="Balkau">Beverley Balkau</name><name sortKey="Cauchi, Stephane" sort="Cauchi, Stephane" uniqKey="Cauchi S" first="Stephane" last="Cauchi">Stephane Cauchi</name><name sortKey="Charpentier, Guillaume" sort="Charpentier, Guillaume" uniqKey="Charpentier G" first="Guillaume" last="Charpentier">Guillaume Charpentier</name><name sortKey="Dina, Christian" sort="Dina, Christian" uniqKey="Dina C" first="Christian" last="Dina">Christian Dina</name><name sortKey="Dina, Christian" sort="Dina, Christian" uniqKey="Dina C" first="Christian" last="Dina">Christian Dina</name><name sortKey="Eury, Elodie" sort="Eury, Elodie" uniqKey="Eury E" first="Elodie" last="Eury">Elodie Eury</name><name sortKey="Froguel, Philippe" sort="Froguel, Philippe" uniqKey="Froguel P" first="Philippe" last="Froguel">Philippe Froguel</name><name sortKey="Lobbens, Stephane" sort="Lobbens, Stephane" uniqKey="Lobbens S" first="Stéphane" last="Lobbens">Stéphane Lobbens</name><name sortKey="Yengo, Loic" sort="Yengo, Loic" uniqKey="Yengo L" first="Loic" last="Yengo">Loic Yengo</name><name sortKey="Yengo, Loic" sort="Yengo, Loic" uniqKey="Yengo L" first="Loic" last="Yengo">Loic Yengo</name></country><country name="Estonie"><noRegion><name sortKey="Esko, Tonu" sort="Esko, Tonu" uniqKey="Esko T" first="Tonu" last="Esko">Tonu Esko</name></noRegion><name sortKey="Esko, Tonu" sort="Esko, Tonu" uniqKey="Esko T" first="Tonu" last="Esko">Tonu Esko</name><name sortKey="Fischer, Krista" sort="Fischer, Krista" uniqKey="Fischer K" first="Krista" last="Fischer">Krista Fischer</name><name sortKey="Krjutskov, Kaarel" sort="Krjutskov, Kaarel" uniqKey="Krjutskov K" first="Kaarel" last="Krjutškov">Kaarel Krjutškov</name><name sortKey="Metspalu, Andres" sort="Metspalu, Andres" uniqKey="Metspalu A" first="Andres" last="Metspalu">Andres Metspalu</name><name sortKey="Metspalu, Andres" sort="Metspalu, Andres" uniqKey="Metspalu A" first="Andres" last="Metspalu">Andres Metspalu</name></country><country name="Finlande"><noRegion><name sortKey="Kinnunen, Leena" sort="Kinnunen, Leena" uniqKey="Kinnunen L" first="Leena" last="Kinnunen">Leena Kinnunen</name></noRegion><name sortKey="Atalay, Mustafa" sort="Atalay, Mustafa" uniqKey="Atalay M" first="Mustafa" last="Atalay">Mustafa Atalay</name><name sortKey="Eriksson, Johan G" sort="Eriksson, Johan G" uniqKey="Eriksson J" first="Johan G" last="Eriksson">Johan G. Eriksson</name><name sortKey="Eriksson, Johan G" sort="Eriksson, Johan G" uniqKey="Eriksson J" first="Johan G" last="Eriksson">Johan G. Eriksson</name><name sortKey="Eriksson, Johan G" sort="Eriksson, Johan G" uniqKey="Eriksson J" first="Johan G" last="Eriksson">Johan G. Eriksson</name><name sortKey="Eriksson, Johan G" sort="Eriksson, Johan G" uniqKey="Eriksson J" first="Johan G" last="Eriksson">Johan G. Eriksson</name><name sortKey="Forsen, Tom" sort="Forsen, Tom" uniqKey="Forsen T" first="Tom" last="Forsen">Tom Forsen</name><name sortKey="Forsen, Tom" sort="Forsen, Tom" uniqKey="Forsen T" first="Tom" last="Forsen">Tom Forsen</name><name sortKey="Isomaa, Bo" sort="Isomaa, Bo" uniqKey="Isomaa B" first="Bo" last="Isomaa">Bo Isomaa</name><name sortKey="Isomaa, Bo" sort="Isomaa, Bo" uniqKey="Isomaa B" first="Bo" last="Isomaa">Bo Isomaa</name><name sortKey="Keinanen Kiukaanniemi, Sirkka M" sort="Keinanen Kiukaanniemi, Sirkka M" uniqKey="Keinanen Kiukaanniemi S" first="Sirkka M" last="Keinanen-Kiukaanniemi">Sirkka M. Keinanen-Kiukaanniemi</name><name sortKey="Keinanen Kiukaanniemi, Sirkka M" sort="Keinanen Kiukaanniemi, Sirkka M" uniqKey="Keinanen Kiukaanniemi S" first="Sirkka M" last="Keinanen-Kiukaanniemi">Sirkka M. Keinanen-Kiukaanniemi</name><name sortKey="Korpi Hyov Lti, Eeva" sort="Korpi Hyov Lti, Eeva" uniqKey="Korpi Hyov Lti E" first="Eeva" last="Korpi-Hyöv Lti">Eeva Korpi-Hyöv Lti</name><name sortKey="Kuusisto, Johanna" sort="Kuusisto, Johanna" uniqKey="Kuusisto J" first="Johanna" last="Kuusisto">Johanna Kuusisto</name><name sortKey="Laakso, Markku" sort="Laakso, Markku" uniqKey="Laakso M" first="Markku" last="Laakso">Markku Laakso</name><name sortKey="Lakka, Timo A" sort="Lakka, Timo A" uniqKey="Lakka T" first="Timo A" last="Lakka">Timo A. Lakka</name><name sortKey="Lakka, Timo A" sort="Lakka, Timo A" uniqKey="Lakka T" first="Timo A" last="Lakka">Timo A. Lakka</name><name sortKey="M Nnisto, Satu" sort="M Nnisto, Satu" uniqKey="M Nnisto S" first="Satu" last="M Nnistö">Satu M Nnistö</name><name sortKey="Peltonen, Leena" sort="Peltonen, Leena" uniqKey="Peltonen L" first="Leena" last="Peltonen">Leena Peltonen</name><name sortKey="Peltonen, Leena" sort="Peltonen, Leena" uniqKey="Peltonen L" first="Leena" last="Peltonen">Leena Peltonen</name><name sortKey="Rauramaa, Rainer" sort="Rauramaa, Rainer" uniqKey="Rauramaa R" first="Rainer" last="Rauramaa">Rainer Rauramaa</name><name sortKey="Rauramaa, Rainer" sort="Rauramaa, Rainer" uniqKey="Rauramaa R" first="Rainer" last="Rauramaa">Rainer Rauramaa</name><name sortKey="Ripatti, Samuli" sort="Ripatti, Samuli" uniqKey="Ripatti S" first="Samuli" last="Ripatti">Samuli Ripatti</name><name sortKey="Ripatti, Samuli" sort="Ripatti, Samuli" uniqKey="Ripatti S" first="Samuli" last="Ripatti">Samuli Ripatti</name><name sortKey="Saaristo, Timo E" sort="Saaristo, Timo E" uniqKey="Saaristo T" first="Timo E" last="Saaristo">Timo E. Saaristo</name><name sortKey="Saaristo, Timo E" sort="Saaristo, Timo E" uniqKey="Saaristo T" first="Timo E" last="Saaristo">Timo E. Saaristo</name><name sortKey="Salomaa, Veikko" sort="Salomaa, Veikko" uniqKey="Salomaa V" first="Veikko" last="Salomaa">Veikko Salomaa</name><name sortKey="Saltevo, Juha" sort="Saltevo, Juha" uniqKey="Saltevo J" first="Juha" last="Saltevo">Juha Saltevo</name><name sortKey="Saramies, Jouko" sort="Saramies, Jouko" uniqKey="Saramies J" first="Jouko" last="Saramies">Jouko Saramies</name><name sortKey="Stan Kova, Alena" sort="Stan Kova, Alena" uniqKey="Stan Kova A" first="Alena" last="Stan Ková">Alena Stan Ková</name><name sortKey="Tikkanen, Emmi" sort="Tikkanen, Emmi" uniqKey="Tikkanen E" first="Emmi" last="Tikkanen">Emmi Tikkanen</name><name sortKey="Tikkanen, Emmi" sort="Tikkanen, Emmi" uniqKey="Tikkanen E" first="Emmi" last="Tikkanen">Emmi Tikkanen</name><name sortKey="Tuomi, Tiinamaija" sort="Tuomi, Tiinamaija" uniqKey="Tuomi T" first="Tiinamaija" last="Tuomi">Tiinamaija Tuomi</name><name sortKey="Tuomi, Tiinamaija" sort="Tuomi, Tiinamaija" uniqKey="Tuomi T" first="Tiinamaija" last="Tuomi">Tiinamaija Tuomi</name><name sortKey="Tuomilehto, Jaakko" sort="Tuomilehto, Jaakko" uniqKey="Tuomilehto J" first="Jaakko" last="Tuomilehto">Jaakko Tuomilehto</name><name sortKey="Tuomilehto, Jaakko" sort="Tuomilehto, Jaakko" uniqKey="Tuomilehto J" first="Jaakko" last="Tuomilehto">Jaakko Tuomilehto</name></country><country name="Suisse"><noRegion><name sortKey="Dimas, Antigone S" sort="Dimas, Antigone S" uniqKey="Dimas A" first="Antigone S" last="Dimas">Antigone S. Dimas</name></noRegion></country><country name="Grèce"><noRegion><name sortKey="Dimas, Antigone S" sort="Dimas, Antigone S" uniqKey="Dimas A" first="Antigone S" last="Dimas">Antigone S. Dimas</name></noRegion><name sortKey="Dedoussis, George" sort="Dedoussis, George" uniqKey="Dedoussis G" first="George" last="Dedoussis">George Dedoussis</name><name sortKey="Rallidis, Loukianos" sort="Rallidis, Loukianos" uniqKey="Rallidis L" first="Loukianos" last="Rallidis">Loukianos Rallidis</name></country><country name="Singapour"><noRegion><name sortKey="Van Dam, Rob M" sort="Van Dam, Rob M" uniqKey="Van Dam R" first="Rob M" last="Van Dam">Rob M. Van Dam</name></noRegion></country><country name="Norvège"><noRegion><name sortKey="Holmen, Oddgeir L" sort="Holmen, Oddgeir L" uniqKey="Holmen O" first="Oddgeir L" last="Holmen">Oddgeir L. Holmen</name></noRegion><name sortKey="Hveem, Kristian" sort="Hveem, Kristian" uniqKey="Hveem K" first="Kristian" last="Hveem">Kristian Hveem</name><name sortKey="Nj Lstad, Inger" sort="Nj Lstad, Inger" uniqKey="Nj Lstad I" first="Inger" last="Nj Lstad">Inger Nj Lstad</name><name sortKey="Platou, Carl Gp" sort="Platou, Carl Gp" uniqKey="Platou C" first="Carl Gp" last="Platou">Carl Gp Platou</name><name sortKey="Platou, Carl Gp" sort="Platou, Carl Gp" uniqKey="Platou C" first="Carl Gp" last="Platou">Carl Gp Platou</name><name sortKey="Wilsgaard, Tom" sort="Wilsgaard, Tom" uniqKey="Wilsgaard T" first="Tom" last="Wilsgaard">Tom Wilsgaard</name></country><country name="Australie"><noRegion><name sortKey="Lawrence, Robert" sort="Lawrence, Robert" uniqKey="Lawrence R" first="Robert" last="Lawrence">Robert Lawrence</name></noRegion><name sortKey="Beilby, John" sort="Beilby, John" uniqKey="Beilby J" first="John" last="Beilby">John Beilby</name><name sortKey="Beilby, John" sort="Beilby, John" uniqKey="Beilby J" first="John" last="Beilby">John Beilby</name><name sortKey="Beilby, John" sort="Beilby, John" uniqKey="Beilby J" first="John" last="Beilby">John Beilby</name><name sortKey="Hui, Jennie" sort="Hui, Jennie" uniqKey="Hui J" first="Jennie" last="Hui">Jennie Hui</name><name sortKey="Hui, Jennie" sort="Hui, Jennie" uniqKey="Hui J" first="Jennie" last="Hui">Jennie Hui</name><name sortKey="Hui, Jennie" sort="Hui, Jennie" uniqKey="Hui J" first="Jennie" last="Hui">Jennie Hui</name><name sortKey="Hui, Jennie" sort="Hui, Jennie" uniqKey="Hui J" first="Jennie" last="Hui">Jennie Hui</name><name sortKey="James, Alan" sort="James, Alan" uniqKey="James A" first="Alan" last="James">Alan James</name><name sortKey="James, Alan" sort="James, Alan" uniqKey="James A" first="Alan" last="James">Alan James</name><name sortKey="James, Alan" sort="James, Alan" uniqKey="James A" first="Alan" last="James">Alan James</name><name sortKey="Musk, Bill" sort="Musk, Bill" uniqKey="Musk B" first="Bill" last="Musk">Bill Musk</name><name sortKey="Musk, Bill" sort="Musk, Bill" uniqKey="Musk B" first="Bill" last="Musk">Bill Musk</name><name sortKey="Musk, Bill" sort="Musk, Bill" uniqKey="Musk B" first="Bill" last="Musk">Bill Musk</name><name sortKey="Musk, Bill" sort="Musk, Bill" uniqKey="Musk B" first="Bill" last="Musk">Bill Musk</name></country><country name="Pays-Bas"><region name="Hollande-Septentrionale"><name sortKey="Sivapalaratnam, Suthesh" sort="Sivapalaratnam, Suthesh" uniqKey="Sivapalaratnam S" first="Suthesh" last="Sivapalaratnam">Suthesh Sivapalaratnam</name></region><name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name><name sortKey="Hovingh, Kees" sort="Hovingh, Kees" uniqKey="Hovingh K" first="Kees" last="Hovingh">Kees Hovingh</name><name sortKey="Sijbrands, Eric" sort="Sijbrands, Eric" uniqKey="Sijbrands E" first="Eric" last="Sijbrands">Eric Sijbrands</name><name sortKey="Trip, Mieke D" sort="Trip, Mieke D" uniqKey="Trip M" first="Mieke D" last="Trip">Mieke D. Trip</name><name sortKey="Uitterlinden89, Andre G" sort="Uitterlinden89, Andre G" uniqKey="Uitterlinden89 A" first="Andre G" last="Uitterlinden89-">Andre G. Uitterlinden89-</name><name sortKey="Uitterlinden89, Andre G" sort="Uitterlinden89, Andre G" uniqKey="Uitterlinden89 A" first="Andre G" last="Uitterlinden89-">Andre G. Uitterlinden89-</name><name sortKey="Uitterlinden89, Andre G" sort="Uitterlinden89, Andre G" uniqKey="Uitterlinden89 A" first="Andre G" last="Uitterlinden89-">Andre G. Uitterlinden89-</name><name sortKey="Van Duijn, Cornelia" sort="Van Duijn, Cornelia" uniqKey="Van Duijn C" first="Cornelia" last="Van Duijn">Cornelia Van Duijn</name><name sortKey="Van Duijn, Cornelia" sort="Van Duijn, Cornelia" uniqKey="Van Duijn C" first="Cornelia" last="Van Duijn">Cornelia Van Duijn</name></country><country name="Italie"><region name="Lombardie"><name sortKey="Veglia, Fabrizio" sort="Veglia, Fabrizio" uniqKey="Veglia F" first="Fabrizio" last="Veglia">Fabrizio Veglia</name></region><name sortKey="Baldassarre, Damiano" sort="Baldassarre, Damiano" uniqKey="Baldassarre D" first="Damiano" last="Baldassarre">Damiano Baldassarre</name><name sortKey="Baldassarre, Damiano" sort="Baldassarre, Damiano" uniqKey="Baldassarre D" first="Damiano" last="Baldassarre">Damiano Baldassarre</name><name sortKey="Tremoli, Elena" sort="Tremoli, Elena" uniqKey="Tremoli E" first="Elena" last="Tremoli">Elena Tremoli</name><name sortKey="Tremoli, Elena" sort="Tremoli, Elena" uniqKey="Tremoli E" first="Elena" last="Tremoli">Elena Tremoli</name></country><country name="Espagne"><region name="Communauté de Madrid"><name sortKey="Tuomilehto, Jaakko" sort="Tuomilehto, Jaakko" uniqKey="Tuomilehto J" first="Jaakko" last="Tuomilehto">Jaakko Tuomilehto</name></region></country><country name="Autriche"><noRegion><name sortKey="Tuomilehto, Jaakko" sort="Tuomilehto, Jaakko" uniqKey="Tuomilehto J" first="Jaakko" last="Tuomilehto">Jaakko Tuomilehto</name></noRegion></country><country name="Pakistan"><noRegion><name sortKey="Saleheen, Danish" sort="Saleheen, Danish" uniqKey="Saleheen D" first="Danish" last="Saleheen">Danish Saleheen</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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